Courses

This webinar, presented by Dr. Dan Beacham, Senior Staff Scientist at Thermo Fisher Scientific, explores fluorescence imaging techniques for analyzing cell surface target internalization in cancer and immunology research. Learn practical considerations for assay development, including platform selection and newly developed probes for studying target internalization, trafficking, phagocytosis, and endocytic mechanisms of action. Discover how to implement concomitant or serial readouts for apoptosis, cell health, and stress as companion assays for Antibody-Drug Conjugate (ADC) labeling, delivery, and lysosomal degradation. Master best practices in live-cell imaging assay development, techniques for leveraging endosomal pH to quantify internalization and trafficking, and the effective use of pathway and endpoint indicators for cell health and stress assessment.

Join a 46-minute webinar led by Dr. Biswajit Das, Senior Principal Scientist at Frederick National Laboratory for Cancer Research, exploring the implementation and validation of Comprehensive Genomic Profiling ctDNA panel in NCI trial research. Learn about the technical aspects of ctDNA profiling assays, focusing on how the panel detects complex biomarkers including tumor mutational burden, microsatellite stability status, mutations, and copy number variants in plasma samples. Discover the analytical validation process and real-world applications through case studies from the NCI-MATCH trial, where the Illumina ctDNA assay successfully identified key mutations in plasma samples when tissue-based testing was unavailable. Examine the impressive results showing over 88% positive percentage agreement in variant identification compared to tissue-based profiling in gynecological cancer cases. Gain valuable insights into the technical performance evaluation of ctDNA profiling assays and their practical application in clinical trials from an expert with more than a decade of experience in genomic assay development and ctDNA biomarker research.

Join a 55-minute webinar featuring Dr. Sherry Dunbar and Dr. Sigrun Badrnya as they explore groundbreaking developments in multiplex protein analysis. Learn about the advanced features of the Luminex xMAP INTELLIFLEX DR-SE instrument and the innovative Invitrogen ProcartaPlex Signaling assays with dual reporter capabilities. Discover how to simultaneously measure up to 16 parameters (8 phosphorylated and 8 total proteins) in a single well, completing analysis from sample to results in just 4 hours. Gain insights into the instrument's dual reporter technology and side eject functionalities, while understanding how ProcartaPlex Signaling assays compare to traditional ELISA and western blot methods. Master the application's large dynamic range and enhanced sensitivity for detecting low-abundance proteins and signaling molecules, particularly in cellular signaling pathway investigations. Perfect for scientists seeking to advance their research through cutting-edge multiplexing technology and innovative assay development.

Join this one-hour webinar to master the fundamentals of multiplexing in quantitative polymerase chain reaction (qPCR) and learn how to successfully implement this powerful technique in your laboratory experiments. Discover how multiplexing provides solutions for increasing sample processing throughput while reducing costs and saving valuable time in the lab. Explore the fundamental principles and mechanisms underlying qPCR multiplexing, with practical guidance on key considerations essential for getting started with this technique. Examine both the advantages and challenges associated with multiplexing, gaining a balanced understanding of its potential benefits and inherent limitations. Learn about the critical factors that must be considered for successful multiplexing implementation, including the paramount importance of using high-quality reagents for optimal results. Conclude with a comprehensive overview of available resources and support options for qPCR multiplexing from Thermo Fisher Scientific. The session is presented by Dr. Chia-An Yen, a dedicated scientist with over 12 years of research experience who currently specializes in qPCR research and development at Thermo Fisher Scientific, where she develops innovative reagents and explores qPCR technology applications. Dr. Yen holds a Ph.D. in Molecular Biology from the University of Southern California and has authored 8 publications on molecular mechanisms of aging, earning recognition through awards including the USC Research Enhancement Fellowship and the Glenn/AFAR Scholarship. Enhance your qPCR skills and streamline your experimental workflows through this comprehensive educational opportunity hosted by Labroots.

Join this one-hour webinar to gain foundational understanding of multiplexing in quantitative polymerase chain reaction (qPCR) and learn how to successfully implement this technique in your experiments. Discover how multiplexing in qPCR provides solutions for increasing sample processing throughput while saving cost and time in the laboratory, despite the many factors that need consideration for successful implementation. Explore the fundamental principles and mechanisms of multiplexing in qPCR through practical guidance on key considerations for getting started. Examine the advantages and challenges associated with multiplexing to understand both its potential and limitations in experimental workflows. Learn about the critical importance of using high-quality reagents and access a comprehensive overview of available resources for qPCR multiplexing support. The session is presented by Dr. Chia-An Yen, a scientist with over 12 years of research experience specializing in qPCR research and development at Thermo Fisher Scientific, who holds a Ph.D. in Molecular Biology from USC and has contributed to innovative reagent development and qPCR technology applications. Enhance your qPCR skills and streamline your experimental workflows through this comprehensive educational opportunity hosted by Labroots.

Explore groundbreaking developments in molecular diagnostics through this 33-minute webinar presented by Professor Feng Li from Sichuan University's College of Chemistry. Discover how CRISPR-based diagnostics (CRISPR-Dx) combined with dynamic DNA assembly are revolutionizing disease detection with unprecedented sensitivity, specificity, and simplicity. Learn about innovative approaches including a plasmonic CRISPR Cas12a assay for detecting grapevine viral infections, a molecular translator method for protein biomarker detection, and the development of ultrasensitive protein assays capable of identifying attomolar concentrations of SARS-CoV-2 antibodies in challenging clinical samples. Gain insights into a novel CRISPR-like assay utilizing RNA-cleaving DNAzyme coupled with isothermal sequence and signal amplification, offering enhanced accessibility and multiplexing capabilities beyond traditional CRISPR-DX methods.

Join a 44-minute webinar led by Andre Alfaro, an experienced developer of in vitro diagnostic tests, exploring the complexities of multiplexed lateral flow assay development in infectious diseases and oncology. Discover the increasing diversity of lateral flow assay applications in the post-pandemic landscape, with a focus on multiplexing strategies to meet market demands and overcome technical limitations. Learn about essential benefits and potential risks of multiplexing, various development approaches, and common obstacles specific to infectious disease and oncology assays. Master strategies for optimizing multiplex assay performance and overcoming development challenges through practical insights drawn from extensive industry experience. Gain valuable knowledge about determining whether multiplexing is appropriate for specific products and how to anticipate potential development pitfalls. Participate in this educational session to earn PACE credits while expanding understanding of this critical diagnostic technology.

Preparation of concentration matrix, protocol, calculation of results and report for assay method validation by HPLC What you'll learn: Assay Method validationPreparation of protocolPreparation of reportConducting calculations I am very glad to launch this course!This course will help you understanding ins and outs about assay method validation for HPLC methods. I have created this course with live demonstration for easy understanding. You will find me executing all activities here in the course.This course will make you MASTER in preparation of concentration matrix for various assay method validation parameters. It will guide you in preparation of protocol as well as report. You will also find information on how to calculate end results for each validation parameter. On top of everything, you will get downloadable versions of required templates and formats

Discover How to Build Web Apps Using R Unlock the power of R, an open source and free software. In this professional certificate you will learn the basics of R to answer your data questions. After learning how to access R and RStudio, install tidyverse, load data from Excel spreadsheet, work with projects, and use R Markdown files you will move on to using R Shiny. In Introduction to R Shiny you will use your R skills to build and deploy web applications. You will further your data visualization skills through web application deployment, user interaction controls, and basic CSS.

Explore recent advancements in lyophilized qPCR reagents in this 21-minute webinar presented by Olivier Bricaud, PhD, Global Market Development Manager for Molecular Biology. Gain insights into the growing demand for rapid, high-performance molecular diagnostic assays across various fields, including infectious diseases, genetic testing, and oncology. Learn about lyophilization techniques, their benefits in qPCR applications, and innovative products like TaqMan Iyo-ready master mixes and Armadillo 96-Well PCR Strip Plates. Discover opportunities for partnerships, licensing, and commercial supply in assay development, and explore the new MDX Assay Developer Program. Earn PACE credits by watching the webinar and following the provided instructions.

Learn to implement standardized antigen-specific T cell response assays for multicenter immune therapy trials in this 59-minute webinar presented by Dr. Megan Levings and Dr. Timothy Tree. Discover how harmonizing immunophenotyping assay designs enables integration of findings across trials, facilitating biomarker identification and validation while revealing cohort-specific features and drug mechanisms. Explore the critical role of antigen-specific T cell response characterization in immunological investigations and patient stratification for future trials. Master robust immune assay techniques designed to detect and characterize rare antigen-specific immune responses directly in peripheral blood, including multimer TCR staining, antigen-induced marker (AIM) assays, and immune cell cytokine production assessment. Examine strategies to reduce inter-laboratory variability in multicenter studies through informative assay designs and complementary methodology utilizing pre-mixed dried antibody panels and dried stimulation mixes with standardized protocols. Review practical applications of these principles through recently published research on T1D autoimmunity studies, including insights from Tatovic et al.'s work published in Nature Medicine 2024.

Watch a 25-minute webinar presented by Dr. Resmi Ravindran, a senior scientist at the Clinical Proteomics Core Lab, University of California Davis Medical Center. Learn about the evaluation of a bead-based multiplex SARS-CoV-2 variant neutralization antibody assay for vaccine research. Gain insights into cutting-edge techniques for assessing vaccine efficacy against different coronavirus variants. Explore the potential applications of this assay in ongoing vaccine development efforts and public health strategies.

Explore a 29-minute webinar presented by Dr. Stephen Angeloni, an expert with over 40 years of experience in biochemical and molecular biology assays. Learn about the development of reliable multiplex assays on xMAP beads for serological and other applications. Discover the importance of proper coupling of capture molecules and accurate mixing of multiple bead regions in multiplex bead mixes. Gain insights into Excel-based workbooks that ensure precise coupling of molecules using different coating levels and maintain reagent stoichiometry during scale-up. Understand how to use Excel-based tools for calculating multiplex mixes in various assay configurations. This presentation offers valuable knowledge for researchers and professionals working with antibody titers and specificity screening.

Explore an innovative approach to cell line development for bispecific antibodies in this 24-minute webinar presented by Dr. Shu Wang, Principal Investigator at Incyte. Learn about the challenges in creating cell lines expressing bispecific antibodies and discover a novel on-chip binding assay developed in collaboration with Bruker Cellular Analysis. Gain insights into the process of labeling ligands, performing on-chip binding assays, and analyzing fluorescence intensity to calculate stoichiometric ratios. Understand how this new method compares to traditional techniques and its potential to streamline cell line development while improving efficiency. Delve into the validation process, exploring the correlation between on-chip binding assay results and actual ratios from bulk pools, mini pools, and clones. Examine the impact of this innovative approach on fed-batch titer and product quality, and discover how it addresses the complexities of heterodimer, halfmer, and homodimer production in bispecific antibodies.

Watch a 46-minute webinar exploring the development and validation of a multiplexed assay for assessing immunogenicity against biologic therapeutics, presented by Dr. Paul Rhyne, a bioassay leader at Gates Medical Research Institute. Learn how biologic-based therapeutics can generate anti-drug immune responses in clinical patients, potentially affecting drug efficacy and patient safety. Discover the traditional tiered approach to anti-drug antibody testing and understand how multiplexing screening and isotyping assays using Luminex® xMAP® Technology can streamline characterization while reducing sample handling. Gain insights into FDA-recommended guidelines for immunogenicity assessments and see how multiplexed assays compare to industry standards. PACE credits are available for registered Labroots members who complete the webinar viewing requirements before October 16, 2026.

The demand for skilled data scientists continues to surge as organizations seek to harness the power of machine learning and data-driven insights. The Data Scientist program, developed by Microsoft and delivered on edX, is designed for learners ready to take their data science skills to the cloud. Through three practical, project-based courses, you’ll explore how to set up and configure the Azure Machine Learning workspace, train models using custom scripts, and deploy models as scalable endpoints. You’ll gain proficiency with tools like Jupyter Notebooks, Python, and Azure ML SDKs—all while learning to operationalize machine learning in real business scenarios. This program is ideal for data professionals, analysts, and aspiring machine learning engineers seeking to build robust, cloud-based ML pipelines. Whether you're transitioning into a data science role or expanding your cloud skill set, this program delivers a strong foundation aligned with industry needs and Azure certification pathways.

This advanced Nanodegree prepares you to tackle data science at scale. Work with AI best practices, build production-ready projects, and gain the confidence to lead data-driven solutions.

Explore a 30-minute webinar presented by Suzie Alarcon, CGMBS, MB(ASCP)ᶜᴹ, focusing on the development and deployment of a saliva-based RT-PCR SARS-CoV-2 detection assay. Learn about a One-Step RT-qPCR assay based on the CDC 2019-Novel Coronavirus Real-Time RT-PCR Diagnostic Panel, designed to detect SARS-CoV-2 particles from heat-inactivated and directly lysed saliva samples. Discover how this method eliminates the need for RNA extraction and utilizes human RNAseP detection as an internal control in a multiplexed reaction. Gain insights into the assay's validation process using positive clinical samples and its high sensitivity of 94.7% or higher in 6μl reactions. Earn PACE credits by watching the webinar and following the provided instructions.

Join Dr. Ting Chan, a research scientist with expertise in pharmacy and precision medicine, for a 16-minute webinar exploring automated and decentralized genomic profiling techniques using plasma cell-free DNA. Learn about cutting-edge developments in precision medicine through the Oncomine Precision Assay methodology, delivered by an expert who combines pharmaceutical sciences knowledge with advanced research experience. Gain valuable insights into genomic profiling techniques while earning PACE credits through Labroots' professional development platform. Master the latest advancements in automated DNA analysis and understand its applications in modern medical diagnostics and treatment planning.

This one-hour webinar features Dr. Maria Alice V. Willrich and Dr. Angela Dispenzieri sharing expert insights on serum free light chain (sFLC) assays for plasma cell disorders. Learn how these tests have advanced prediction, diagnosis, and monitoring of conditions like Multiple Myeloma, its precursors (MGUS and smoldering myeloma), and Amyloidosis. Explore the interchangeability of assay platforms, updated guidelines for monoclonal gammopathies, and the 2023 consensus for cardiac amyloidosis. Gain valuable knowledge about reference intervals, method selection, and strategies to enhance assay specificity for improved testing accuracy. After watching, registered Labroots members can earn PACE credits valid until March 11, 2027.