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Motors and Motor Control Circuits course thumbnail

Coursera

Certificate

Motors and Motor Control Circuits

Electrical Engineering
Embedded Systems
Motor Control

This course can also be taken for academic credit as ECEA 5341, part of CU Boulder’s Master of Science in Electrical Engineering degree. This is our second course in our specialization on Embedding Sensor and Motors. To get the most out of this course, you should first take our first course entitled Sensors and Sensor Circuits. Our first course gives you a tutorial on how to use the hardware and software development kit we have chosen for the lab exercises. This second course assumes that you already know how to use the kit. After taking this course, you will be able to: ● Understand how to specify the proper AC or DC motor for a machine design. ● Integrate the motor to a machine, based on analysis of motor equations for voltage, current, torque and speed. ● Implement the motor and accompanying rotary sensor into a motor control circuit in both hardware and software. ● Add a motor and motor control circuit into a microprocessor based development kit. ● Create hardware and firmware to process motor feedback data to a microprocessor for further evaluation. You will need to buy the following components to do the two course projects based on the videos in this module. Note that if you have already purchased the PSOC 5LP PROTOTYPING KIT, you do not need to buy it again. These parts may be purchased off the Digikey web site, www. Digikey.com. Or, you may obtain the specs from the site, and purchase them elsewhere. These are the part numbers for the above table, the lab on Motor Voltage and Current Measurement. You can copy and paste them into the search engine on the Digikey web site. You need one of each except for the AA batteries (N107-ND), which you would need 3. 428-3390-ND P14355-ND FQU13N10LTU-ND N107-ND 1N5393-E3/54GICT-ND RNF14FTD1K00CT-ND P0.62W-1BK-ND Additional equipment needed: • Wire - various gauges and lengths • Breadboard • Oscilloscope – suggested models are: o PICOSCOPE 2204A-D2 available on www.digikey.com or o Digilent 410-324 | OpenScope MZ available on www.newark.com Depending on your budget, you can also investigate these models: o Hantek HT6022BE20MHz - https://www.amazon.com/dp/B009H4AYII o SainSmart DSO212 - https://www.amazon.com/dp/B074QBQNB7 o PoScope Mega50 USB - https://www.robotshop.com/en/poscope-mega50-usb-mso-oscilloscope.html o ADALM2000 - https://www.digikey.com/en/products/detail/analog-devices-inc./ADALM2000/7019661

Types of Motors Used in EV - Single, Dual, Three & Four Motor Configuration in EV course thumbnail
FREE

YouTube

Types of Motors Used in EV - Single, Dual, Three & Four Motor Configuration in EV

Automotive Technology
Applied Science
Electric Vehicles

Explore the various types of motors used in electric vehicles (EVs) and their configurations in this comprehensive 16-minute video. Learn about the fundamental workings of electric motors and their role in powering EVs. Discover seven different types of electric motors, including brushed and brushless DC motors, permanent magnet synchronous motors, and induction motors. Delve into the various powertrain configurations, from single-motor setups to more advanced dual, triple, and four-motor arrangements. Gain insights into how these different configurations affect power delivery and vehicle performance. Perfect for those interested in EV technology and automotive engineering.

Electric Vehicle Battery Charging Motor Components - Basics course thumbnail

Udemy

Certificate

Electric Vehicle Battery Charging Motor Components - Basics

Battery Management Systems
Electric Vehicles
Electrical Engineering

ELECTRIC VEHICLE BASICS | LITHIUM ION BATTERY MANAGEMENT SYSTEM | CHARGING TECHNOLOGY | MOTOR | EV COMPONENT | BMS | JOB What you'll learn: Students will get a complete overview about each and every components of an Electric VehicleStudents will learn all about Lithium ion Batteries. Form factors, Chemistry of Lithium ion Battery, Assembly of Lithium ion batteryStudents will get a detailed understanding about Battery management system. It includes Battery protections, Cell Balancing, state of charge Estimation and Selection of IC to design your own BMSStudents will learn about the various techniques to implement Battery thermal management system "Lithium Ion Battery and Battery Management System for an EV" is a BASIC course on Electric Vehicle operation, Components, Batteries and its types.This course covers working principles of all the components used inside an Electric vehicle. A new comer, EV enthusiast, EV owner, Business owners, Managers, Students, professionals, hobbyists should take up this course if they have even 1% interest in Electric Vehicles.An industrial perspective has been added to this course to make it very real to connect Universities to Industries. It is a combination of theory, quizzes, Practical examples and mathematical calculation assignments. This course introduces you to the Electric vehicle world and discusses each and every component inside it in big detail. EVSE, BLDC Motors, Motor Controllers, DC-DC Converters, Chargers, Power train concepts are discussed with very simple understanding. In depth coverage of Lithium ion batteries is done in this course which shares approximately 40% cost of an Electric vehicle. It includes various Chemistry of Lithium ion batteries like NMC, NCA, LFP, LTO, Solid state batteries and many more. Battery pack connections and assembly is a key part in Batteries. I have tried to cover various Cell configurations to develop your own battery pack in a very simple language. This course covers Battery Management System from the basic level. You will learn about various features of BMS in more detail. It covers Cell balancing, State of Charge estimation, coulomb counting and Kalman Filters. This Course also helps you to select an appropriate IC for designing a Battery management system. Thermal management system is the most critical part for an EV battery. This course discusses various techniques used in the industry for cooling an Electric vehicle battery Pack.

Electric Vehicle Technology - A Beginner's Course course thumbnail

Udemy

Certificate

Electric Vehicle Technology - A Beginner's Course

Electric Vehicles
Electrical Engineering
Testing

Electric Vehicle Tech & Components | Motors | Battery management system | Charging technology | Electric Vehicle testing What you'll learn: Selection of E – motors for Electric Vehicles- BLDC/PMSM/INDUCTION/SynR MOTORSMotor Control Technology for Electric Vehicle applicationsLithium Batteries and Battery Pack Design for Electric & Hybrid Vehicle ApplicationLithium Ion Battery Management SystemsSafety, Testing, Regulations, and Standards of Electric and Hybrid vehicle'sPowertrain Sizing Calculation Procedure and Practice ProblemsCase Study on Nissan Leaf electric vehicle. Upon completion of the academy, participants will be able to:Complete Overview of all High Voltage components involved in an electric or hybrid Vehicle.Cradle-to-grave of an automotive OEM to understand the effect of electric vehicle on the carbon footprint.Describe the main hybrid and electric vehicle development considerations and performance requirements for various vehicle systemApply the operation of brushless dc and induction motors to HEV and EV vehiclesDefine the torque speed curves for motors and the application to electric and hybrid electric vehiclesDefine and analyze battery operation and performance requirements for HEV, PHEV, EREV and full electric vehicle applicationsEstimate the size of a cell to meet a specific requirementDescribe the functions performed by a Battery Management System (BMS)Understand different thermal management methodologies applied for the battery pack systems and their challengesExplain different approaches to estimating state of charge, state of health, power and energyCompare and contrast the various industry and regulatory standards for hybrid vehicle components, batteries, and charging systemsIdentify how to define key vehicle system requirements and select and size system components that best meet those requirementsUnderstand various testing and regulatory requirements for electric vehicle and components at both system and subsystem level.Understand the challenges in meeting the safety regulations at international level.Understand the drawbacks of current testing procedures applied by the international testing agencies for electric and hybrid vehicles.

How Does In-Wheel Motor Technology Work - Four Motor Drive and Torque Vectoring course thumbnail
FREE

YouTube

How Does In-Wheel Motor Technology Work - Four Motor Drive and Torque Vectoring

Automotive Technology
Applied Science
Electric Vehicles

Explore the innovative technology of in-wheel motors and torque vectoring in electric vehicles through this informative 15-minute video. Discover how in-wheel motors work, their design principles, and power capabilities. Learn about the differences between in-wheel motor systems and traditional drivetrains, and understand the concept of torque vectoring. Examine the efficiency of in-wheel motors, their potential future in the EV industry, and see a real-world application in the Rivian R1T truck. Gain insights into the advantages and disadvantages of this cutting-edge technology, and understand its impact on the future of electric vehicle design and performance.

Musculoskeletal System - Neuromuscular Junction - Neuromuscular Transmission course thumbnail
FREE

YouTube

Musculoskeletal System - Neuromuscular Junction - Neuromuscular Transmission

Musculoskeletal System
Anatomy
Action potentials

Dive into a comprehensive lecture on the neuromuscular junction and neuromuscular transmission, focusing on the action potentials carried by the alpha motor neuron, factors influencing acetylcholine release, and the synaptoproteins involved in this process. Explore the intricacies of the musculoskeletal system, including the long motor neuron, acetylcholine production, mitochondrial function, and protein transporters. Gain a thorough understanding of how acetylcholine is transported and the repolarization process in neuromuscular transmission. This in-depth video, presented by Professor Zach Murphy, serves as the first part of a series dedicated to unraveling the complexities of the neuromuscular system.

Molecules, Movement, and Motors - Shedding Light on Motor Function course thumbnail
FREE

YouTube

Molecules, Movement, and Motors - Shedding Light on Motor Function

Biophysics
Physics
Biochemistry

Explore the fascinating world of molecular motors in this lecture featuring Steven M. Block from Stanford University. Delve into single-molecule biophysics, focusing on kinesin and its movement mechanisms. Learn about optical traps, force clamps, and the handover-hand motion of kinesin. Discover how experiments, statistics, and the Michaelis-Menten curve contribute to understanding molecular mechanics. Gain insights into the chemistry and mechanics behind kinesin's function, and explore the concept of "Robokinesin." Conclude with closing remarks by Samara Reck-Peterson from Harvard Medical School, tying together the intricate details of molecular movement and motor function.

Parkinson's Disease Motor Severity Associated with Synaptic Density and Dopamine Transporter PET - BrainMap Lecture course thumbnail
FREE

YouTube

Parkinson's Disease Motor Severity Associated with Synaptic Density and Dopamine Transporter PET - BrainMap Lecture

Parkinson's Disease
Neurology
Health Care

Explore a comprehensive lecture on the relationship between Parkinson's disease motor severity, synaptic density, and dopamine transporter PET imaging. Delivered by Dr. David Matuskey from Yale University, this 38-minute presentation delves into cutting-edge research findings in the field of neurodegenerative disorders. Gain insights into the latest developments in neuroimaging techniques and their applications in understanding Parkinson's disease progression. Learn how PET imaging can be utilized to assess synaptic density and dopamine transporter activity, and how these factors correlate with the severity of motor symptoms in Parkinson's patients. Discover the implications of this research for potential diagnostic tools and treatment strategies in the management of Parkinson's disease.

Electric Vehicle Crash Course course thumbnail

Udemy

Certificate

Electric Vehicle Crash Course

Electric Vehicles
Electrical Engineering
Mechanical Engineering

Everything from EV Project Calculations to Simulation and Analysis of Electric Vehicle System with MATLAB What you'll learn: How to calculate required Average Motor PowerHow to calculate Gear RatioHow to calculate Battery & Vehicle RangeHow to obtain Rated Vehicle SpeedHow to obtain torque developed by motorHow to obtain motor efficiencyHow to obtain rated vehicle speedHow to calculate cost of electricity bill for single chargeHow to calculate running cost of vehicle for per km travelHow to calculate battery replacement cost for per kmHow to estimate charging time from C-rating of batteryAbout different Motors, Controller, Battery, Throttle and other Mechanical aspects.Starting Electric Vehicle Project and Building Prototype.Connection of Motor, Controller and other Accessories.Type of Electric Bicycle & PASAbout Electric Vehicle Industries of India and Startups5+ Practice AssignementsNew Module: Electric Vehicle Engineering Vehicles to learn all engineering aspectsVehicle Dynamics, Vehicle Performance Parameters , Driving Cycle, Force-speed characteristicsElectric Motor, Torque-speed Characteristics, Suitability and ComparisonElectric Motor Drive - Drive train -Power TrainEnergy Sources, Fuel Cell, Ultracapacitor, Flywheel, BatteryElectric Vehicle Configuration based on Electric Motor and based on Energy SourcesHow to develop a mathematical model of the vehicleHow to develop a MATLAB simulation model of the specific vehicleHow to develop simulation model of specific electric motorHow to connect developed vehicle model to the electric vehicle model with a passive loading schemeHow to use this model for predicting the performance of the systemEffect of Rolling Resistance on EV model This comprehensive course, "Electric Vehicle Crash Course," is tailored to suit individuals of all ages and backgrounds, ranging from high school students to seasoned researchers. It serves as a go-to resource for mastering the in-demand skill set of Electric Vehicle technology. Whether you're just starting out or looking to deepen your understanding, this course covers everything from the basics to advanced topics. Continuously updated with the latest resources and based on student feedback, it stands as the ultimate online resource for those considering a career in the Electric Vehicle industry, all while remaining accessible and affordable. Module 1 - Electric Vehicle Project Guide (Chapter 1 -7): In this module, participants will delve into the essentials of launching an Electric Vehicle project from scratch. Covering crucial calculations such as power requirements, gear ratios, battery range, and more, this section lays the foundation for understanding the practical aspects of Electric Vehicle design. From estimating costs to building prototypes and exploring different Electric Bicycle types, participants will gain hands-on experience in initiating and executing Electric Vehicle projects.Module 2 - Electric Vehicle Industry and Startups (Chapter 8): Participants will explore the landscape of the Electric Vehicle industry, focusing on key players and startups within the Indian context. Understanding the industry's current state and emerging trends provides valuable insights for aspiring professionals and entrepreneurs alike.Module 3 - Electric Vehicle Engineering (Chapter 9-13): This module delves into the engineering principles underlying Electric Vehicles, covering topics such as vehicle dynamics, motor characteristics, energy sources, and vehicle configurations. Through a comprehensive examination of Electric Vehicle components and systems, participants gain a deep understanding of the technical aspects driving innovation in this field.Module 4 - Simulation and Analysis of Electric Vehicle System with MATLAB (Chapter 14-21): The final module equips participants with the tools and techniques necessary for simulating and analyzing Electric Vehicle systems using MATLAB. From developing mathematical models to solving differential equations and integrating vehicle and motor simulation models, participants learn how to predict and optimize system performance using advanced computational methods.By the end of this course, participants will emerge as competent Electric Vehicle enthusiasts, equipped with the knowledge and skills needed to navigate the dynamic landscape of Electric Vehicle technology with confidence. Whether pursuing further studies or entering the industry directly, graduates of this course will be well-prepared to make meaningful contributions to the advancement of Electric Vehicle technology.

Introduction to Kubernetes Operators and the Operator Framework course thumbnail
FREE

YouTube

Introduction to Kubernetes Operators and the Operator Framework

Kubernetes Operators
Kubernetes
DevOps

Dive into the world of Kubernetes Operators and the Operator Framework in this comprehensive 1 hour 50 minute tutorial presented by Matt Dorn and Michael Hrivnak from Red Hat. Gain a solid understanding of these powerful tools for automating and managing complex applications on Kubernetes clusters. Learn how to leverage Operators to streamline deployment, scaling, and maintenance of containerized applications, while exploring the Operator Framework's capabilities for developing and managing custom Operators efficiently.

Introduction to the Operator SDK - Building Kubernetes Operators course thumbnail
FREE

YouTube

Introduction to the Operator SDK - Building Kubernetes Operators

Kubernetes Operators
Kubernetes
DevOps

Explore the fundamentals of the Operator SDK in this 48-minute tutorial from Rawkode Academy. Learn about the Operator Framework, an open-source toolkit for managing Kubernetes native applications, and discover how the Operator SDK simplifies the process of building, testing, and packaging Operators. Dive into creating a new operator, adding custom resource definitions, implementing business logic, and deploying operators on a Kubernetes cluster. Gain insights into high-level APIs, code generation tools, and extensions for common Operator use cases. Follow along as the instructor demonstrates practical examples and shares valuable resources for further learning.

Electric Motor Design for Electric Vehicle's - Case Studies course thumbnail

Udemy

Certificate

Electric Motor Design for Electric Vehicle's - Case Studies

Electric Motors
Electrical Engineering
Electric Vehicles

Advanced Level - Case studies on electric powertrain technology of automotive OEM's What you'll learn: Electric Vehicle Drive system TargetsInterior PM Magnet Motors and Induction MotorsMagnet Arrangements & Impacts on Motor PerformancePhysical Design Changes for Efficiency ImprovementLight Weight design and manufacturing Techniques for EV propulsion motorsSystem Integration & Impacts on NVHAdvanced Motor Sensor applications for EV’s and HEV’s The participant will be able to understand the power train level targets to be met by automotive manufacturers in the upcoming years and its effect on development of E motors.Electric Drive system TargetsCO2 footprint and driving forces for electrification.This section will discuss on various measures taken by the research team of Nissan motors for improved electric powertrain performance and efficiency.Evolution of Nissan Leaf - 2011 to 2013 to 2018Interior PM Magnet Motors and Induction MotorsMagnet Arrangements & Impacts on Motor PerformanceReduction of rare earth elements for motor magnetsPhysical Design Changes for Efficiency ImprovementLight Weight design and manufacturing Techniques for EV propulsion motorsSystem Integration & Impacts on NVHSensitivity Analysis & NVH OptimizationNVH Optimization and its Effects on motor torque & acceleration performanceHarmonic Content of Radial Force DensityOptimization of Slot, slot liner, Poles & WindingThe General Motors Cadillac Hybrid uses Two motors for the powertrain. Induction and PMSM Motors. Here the participants will be able to understand the background of this motor selection strategyImpacts on Efficiency of motor and inverter systemUnderstanding the usage profile of the Induction and PMSM Machines for Hybrid Vehicle applicationsStrategies for torque ripple reduction of the induction and PMSM drivesThis section focuses on the key sensor technology applied by the automotive manufacturers in their electric and hybrid vehicle powertrains.Advanced Sensor applications for Better Control of EV’s and HEV’sSelection Criteria for Position sensorsSensor mounting methodologies and its significance on accuracySensor Angle Calculation and Error DefinitionComparison of Peak to Peak mechanical angle errorExemplary illustration of a resolver rotor position signal processing system.

Motor Starter Circuits (Motor Control) course thumbnail

Udemy

Certificate

Motor Starter Circuits (Motor Control)

Motor Control
Robotics
Circuit Design

Motor starter schematics or wiring drawings. Learn to design power & control circuits for motor starters What you'll learn: Concept of power and control circuitsDesigning a circuit : Starter CircuitsHow to design schematicsDOL circuitRDOL circuitStart - Delta CircuitSoft starter circuitVFD starter circuitUnderstand how page connectors work Motor Starter Circuits (Motor Controls) is an intermediate course to learn schematics or electrical drawing (power and control circuits) for Motor Starters. We have covered various concepts that are required to design schematics. Before you start this course make sure your basics on Electrical Schematics is clear. You can also take our Electrical Schematics (Industrial Controls) course for learning basics. We are also thrilled to share that this course has earned the high ranking of 9.4/10 by CourseMarks and ranks in the TOP 4% of 94,680 courses!Some of the topics that you will come across in this course are:1) Basic details on schematics - What is schematic ? Where is it used ? Why is it needed?2) Reading & Understanding Schematic - Title block, Disclaimer, Template, Designations, Cross-referencing, Legends etc.3) Symbols & Switchgears - Electrical Symbols along with definition & images. Key technical details about switchgear like circuit breakers, Contactors Isolators, Meters , Indicators & Protection devices a)Learn Off load & On Load devices b) Difference between isolators & circuit breakers c) NO& NC contacts d) Power & Auxiliary Contactor - contact numbering, advantages & limitations etc. e) Instrument Transformers f) Protection Devices4)Designing circuit - in a step by step method - DOLMotor Starter Circuit Control of motors - Star / Stop, TripHold-on ContactIndication circuitsLocal remote Auto manual operations 5) Basics of electrical interlocking6) Basics of Metering Circuits7) Application in Switchboards and practice questions.

Bitwise Operators, For Loops, Operator Precedence and Variable Scoping course thumbnail
FREE

YouTube

Bitwise Operators, For Loops, Operator Precedence and Variable Scoping

Bitwise Operators
Algorithms
Problem Solving

Learn essential programming concepts including bitwise operators, for loops, operator precedence, associativity, and variable scoping in this comprehensive video tutorial. Explore practical applications through LeetCode problem-solving sessions. Gain hands-on experience with bitwise AND, OR, NOT, and XOR operations, as well as left and right shift operators. Master for loop syntax and usage, tackling problems like calculating sums, generating Fibonacci sequences, and identifying prime numbers. Understand variable scope intricacies and operator precedence rules to write more efficient code. Apply newly acquired knowledge to solve two LeetCode challenges, reinforcing learning through real-world coding scenarios.

Revolutionizing African Mobility course thumbnail
FREE

YouTube

Revolutionizing African Mobility

TEDx
Electric Vehicles
Sustainable Transportation

Explore the transformative journey of electric mobility in Africa through this TEDxLubowa talk. Discover how Kiira Motors, a Makerere University project, is developing innovative electric vehicles tailored for the African market. Learn about the potential of these vehicles to reduce carbon emissions, improve air quality, and create job opportunities. Gain insights into the latest innovations from Kiira Motors, including the Kayoola EVS and Kayoola bus. Hear from Thatcher Mpanga Nakimuli, leader of the Product Design Division at Kiira Motors Corporation, as she shares her expertise in developing groundbreaking mobility solutions for Uganda. Understand the impact of the Kiira Vehicle Plant, the first green E-Mobility plant in Africa, and its potential to produce 5,000 vehicles annually at full capacity. Delve into the future of transportation in Africa and the role of electric vehicles in shaping a more sustainable and economically vibrant continent.

Maintenance of New Energy Vehicles course thumbnail
FREE

XuetangX

Maintenance of New Energy Vehicles

Electric Vehicles
Electrical Engineering
Electrical Systems

“Maintenance of New Energy Vehicles” course is an essential curriculum specifically designed for the field of new energy vehicle technology, aiming to equip students with the skills needed for the maintenance and upkeep of new energy vehicles. The course covers core knowledge such as battery management systems, motor control technology, and electronic control system diagnostics and repair, and is combined with abundant practical operations to ensure that students can apply theoretical knowledge to their actual work. Through this course, students will gain a comprehensive understanding of the structure and principles of new energy vehicles, master the methods of maintaining and servicing key components, and develop the ability to independently diagnose and troubleshoot issues. This course is suitable for students majoring in new energy vehicle technology, individuals aspiring to engage in new energy vehicle repair, after-sales service, or technical support, as well as in-service personnel looking to enhance their new energy vehicle maintenance skills. With the booming development of the new energy vehicle industry, the demand for professional maintenance talent is increasingly strong. This course will help students master cutting-edge industry technologies, enhance their career competitiveness, and lay a solid foundation for their future career development.

Smart Vehicles, Secure Data - Recreating Vehicle Environments for Privacy-Preserving Machine Learning course thumbnail
FREE

YouTube

Smart Vehicles, Secure Data - Recreating Vehicle Environments for Privacy-Preserving Machine Learning

Privacy-Preserving Machine Learning
Machine Learning
Cloud Computing

Explore how to implement privacy-preserving machine learning for connected vehicles in this 31-minute conference talk. Discover the critical importance of protecting personal and sensitive data generated by modern vehicles while enabling advanced ML capabilities. Learn about Trusted Execution Environments (TEEs) and Azure Confidential Computing as solutions for maintaining data privacy throughout the entire machine learning pipeline in cloud environments. Understand the innovative approach to recreating vehicle environments in the cloud where sensitive information remains protected during model training, inference, and deployment phases. Gain insights from Mercedes-Benz R&D North America's real-world implementation of secure, privacy-respecting personalized systems designed for next-generation connected vehicles, presented by Senior Data Scientist Frankie Cancino.

The Most Important Motor for Our Electrical Future - Permanent Magnet Synchronous Motors course thumbnail
FREE

YouTube

The Most Important Motor for Our Electrical Future - Permanent Magnet Synchronous Motors

Electric Motors
Electrical Engineering
Magnetic Fields

Explore the Permanent Magnet Synchronous Motor (PMSM) in this 10-minute educational video that examines why this motor type is crucial for electrical applications of the future. Learn about PMSM applications across various industries and understand the key differences between PMSM and BLDC (Brushless DC) motors through detailed behavioral analysis. Discover how BLDC motors operate compared to PMSM functionality, and gain insights into driving PMSM systems using sine wave controllers with practical demonstrations. Examine the significant advantages that make PMSM motors superior for modern electrical systems, including their efficiency, control precision, and performance characteristics. The presentation covers technical concepts in an accessible manner, making complex motor theory understandable for electronics enthusiasts and engineers looking to implement these motors in their projects.

Insulin and Glucose Transporters - Explained course thumbnail
FREE

YouTube

Insulin and Glucose Transporters - Explained

Endocrinology
Health Care
Physiology

Explore a comprehensive medical lecture on insulin and glucose transporters. Delve into the intricate mechanisms of glucose regulation in the body, focusing on the role of insulin and various glucose transporter proteins. Learn about the physiological processes involved in maintaining blood glucose levels, the function of insulin in facilitating glucose uptake by cells, and the different types of glucose transporters found in various tissues. Gain a deep understanding of how these systems work together to maintain homeostasis and the potential implications when they malfunction. This in-depth presentation is ideal for medical students, healthcare professionals, and anyone interested in advanced topics in human physiology and metabolism.

Large-Scale Conformational Transitions in Membrane Transporters Using Advanced Molecular Dynamics Simulations course thumbnail
FREE

YouTube

Large-Scale Conformational Transitions in Membrane Transporters Using Advanced Molecular Dynamics Simulations

Molecular Dynamics
Computational Chemistry
Chemistry

Explore advanced molecular dynamics simulation techniques in this comprehensive research seminar from the Broad Institute's Models, Inference and Algorithms series. Delve into the computational biophysics approaches for studying large-scale conformational transitions in membrane transporters, essential cellular gatekeepers responsible for moving molecules across cell membranes. Learn about the alternating-access mechanism governing transporter function through inward-facing and outward-facing states, and understand how various simulation techniques are combined to characterize these transitions. Master the process of defining collective variables, conducting driven MD simulations, implementing the string method with swarms of trajectories, and performing bias-exchange umbrella sampling to generate detailed free energy profiles. Examine practical applications of these methods to specific transporters like NaCT, Glt Ph, and GlpT, gaining insights into how structural dynamics influence cellular transport mechanisms and potential drug development strategies. The presentation includes both a primer on computational methodology and detailed case studies demonstrating real-world applications in understanding transporter function and dysfunction in disease contexts.