Senior Director of Value, Access, & Trade (Commercial)

Back to all jobs Senior Director of Value, Access, & Trade (Commercial) Posted 30-Apr-2026 (EST) Frederick, MD, USA 250,000-325,000 per year

Salary Full Time Email Me Similar Jobs Email Me This Job Location:

Hybrid Role - based in Princeton, NJ or Frederick, MD Reports to:

Head of Commercial About Cartesian Therapeutics:

Cartesian Therapeutics is a clinical-stage biotechnology company developing m

RNA CAR-T

therapies for autoimmune diseases. Our mission is to expand the reach of cell therapy to patients living with serious autoimmune conditions through scientific rigor, collaboration, and innovation. About the

Role:

As we look ahead to the upcoming completion of our Ph3 Generalized Myasthenia Gravis trial, along with the continued progression of our trials in Myositis and Juvenile Dermatomyositis, Cartesian is further building-out our Commercial Organization. Thus, we are seeking a Head of Value, Access, & Trade , which will report to the Head of Commercial and serve as a key member of the Commercial leadership team.

Key Responsibilities:

Market Access Strategy & Value Architecture:

Develop and lead an integrated market access and value strategy to support successful commercialization, ensuring optimal payer positioning, evidence generation, pricing, reimbursement, and access

Pricing, Contracting, & Gross-to-Net Strategy:

Establish and execute pricing and contracting strategies, including gross-to-net optimization, to balance access and value realization while ensuring compliance with all government pricing and reporting requirements; Support the Head of Commercial in the design and implementation of pricing and contracting governance frameworks to ensure executive alignment, disciplined decision-making, and compliant execution

Payer Engagement & Negotiation:

Build and maintain senior-level relationships and lead complex negotiations (national & regional commercial payers & government entities) to secure and sustain favorable access & reimbursement outcomes

Value Proposition, Evidence & Payer Marketing :

Define and deliver differentiated payer value propositions supported by robust clinical, economic, and real-world evidence strategies; lead payer marketing, payer market-shaping, and the development & deployment of HEOR resources to drive education and access; and implement rigorous measurement for impact and continuous improvement

Reimbursement Strategy :

Design and implement a reimbursement model aligned to HCO business models, site-of-care nuances, and company economics to ensure profitable patient access and favorable customer experience

Trade & Distribution Model:

Architect and optimize specialty distribution and trade (including government licensing) ensuring seamless and compliant product flow to patients

Field Market Access Leadership :

Build and lead high-performing field teams (payer accounts/NAMs and field reimbursement) to execute access strategy, drive pull-through, and deliver best-in-class stakeholder engagement

Cross-Functional Collaboration :

Partner closely with key commercial peers, as well as leadership across medical affairs, finance, regulatory, legal/compliance, manufacturing, and supply chain to ensure aligned and integrated execution of access strategies across the product lifecycle

Team Development & Leadership:

Recruit, develop, and lead a high-performing, agile market access team; foster a collaborative, accountable, and patient-centric culture aligned with company values.

Qualifications:

BioPharma Experience:

15+ years of progressive BioPharma market access leadership experience across payer strategy, pricing, contracting, reimbursement, trade/distribution, and field execution, with demonstrated success operating at the executive level within a Biotech initiating a first commercial launch

Leadership Profile :

Purpose-driven leader that values and role-models innovation, collaboration, integrity, and patient-centric thinking. Proven "player-coach" with the agility & humility to operate seamlessly between strategy and execution; known for building and leading high-performing teams and driving impact in resource-constrained, fast-paced, high-science environments

Market Access Expertise :

Deep expertise in U.S. payer & reimbursement landscape, including government and commercial payers, buy-and-bill dynamics, trade & specialty distribution, pricing frameworks, gross-to-net, policy considerations, site of care models, and compliant payer engagement (including PIE)

Therapeutic Experience :

Experience within cell and/or gene therapy, rare disease, neurology, rheumatology, and/or hematology/oncology strongly preferred, including successful launch of novel or first-in-class therapies

Strategic & Analytical Excellence :

Strong ability to translate clinical and economic data into compelling value narratives and access strategies; experience linking access strategy to forecasting, financial planning, and commercial performance

Collaboration & Influence :

Exceptional communication, executive presence, and stakeholder influence skills, with a highly collaborative, cross-functional mindset

Education :

Advanced degree (MBA, MPH, PharmD, PhD, or equivalent) preferred ; relevant work experience will be considered

Travel Expectations:

~30-40% travel, increasing to 40-60% during pre-launch and payer-critical periods