Associate Director, Research Portfolio Management & Scientific Operations

Associate Director, Research Portfolio Management & Scientific Operations Employer Modex Therapeutics Ltd. Location Weston, Massachusetts Salary $197000 - $212000 per year Start date May 22, 2026 View more categories View less categories Discipline Manufacturing & Production , Operations , Regulatory Required Education Masters Degree/MBA Position Type Full time Hotbed Genetown Apply now Save job Click to add the job to your shortlist You need to sign in or create an account to save a job. Send job Job Details Company Job Details Company Overview ModeX Therapeutics, an OPKO Health company, is the leading clinical-stage biopharmaceutical company developing unique and proprietary-multispecific therapeutics. Its MSTAR platform unites the power of multiple biologics in a single molecule to create multispecific antibodies that bind four or more targets with unprecedented versatility and potency for complex diseases. Its promising first-in-class immunology pipeline includes candidates against immune diseases, including cancer (both solid and hematologic tumors), immune impairment, as well as several of the world's most pressing viral threats. Its founding team includes globally recognized medical innovators with proven track records of delivering breakthroughs for patients. ModeX is based in Weston, Massachusetts. For more information, please visit www.modextx.com . Job Description ModeX Therapeutics is seeking a highly skilled Associate Director or Director, Research Portfolio Management & Scientific Operations to partner closely with the Chief Scientific Officer (CSO) and scientific leadership team to translate scientific strategy into actionable portfolio plans, guide programs through governance processes, and align cross-functional research and translational activities with key program priorities. The successful candidate will bring strong scientific judgment, industry experience in portfolio and program management, and a disciplined approach to execution across discovery, preclinical, translational, and early clinical development activities. This role will be responsible for driving alignment across program scope, timelines, budgets, resources, and key decision points, while also supporting high-quality scientific communications. The individual will help translate complex biological data into clear, compelling narratives for both internal and external stakeholders. Key Responsibilities Portfolio Governance & Scientific Operations Partner with the CSO and R D leadership to establish and maintain fit-for-purpose portfolio governance and operational processes. Coordinate portfolio review meetings, stage-gate processes, executive reviews, and cross-functional decision-making activities. Prepare governance agendas, briefing materials, decision logs, and action trackers. Drive alignment between scientific priorities, portfolio strategy, and resource allocation. Develop and maintain portfolio dashboards and reporting tools that summarize program status, milestones, risks, dependencies, and R D budgets. Research Portfolio & Program Management Support integrated planning across discovery, preclinical, translational, CMC, and early clinical-stage programs. Build and manage cross-functional program plans, including scope, timelines, milestones, resource assumptions, risks, dependencies, and decision points. Support portfolio prioritization, business development activities, scenario planning, and strategic resource allocation discussions. Strategic Communications & Scientific Engagement Translate scientific and organizational priorities into executable plans and operating rhythms. Develop high-quality scientific and strategic presentations for executive leadership meetings, Board presentations, investor interactions, and partnership discussions. Support scientific publications, congress materials, grant applications, manuscripts, business development materials, and external communications in collaboration with functional leaders and Corporate Communications. Lead the planning and execution of Key Opinion Leader (KOL) and Scientific Advisory Board (SAB) interactions, including agenda development, content preparation, insight capture, and follow-up actions. Synthesize external scientific feedback into actionable recommendations for program and portfolio teams. Qualifications Required Qualifications PhD or equivalent advanced degree in Immunology, Oncology, Cell Biology, Molecular Biology, or a related discipline. 8+ years of relevant biotech or pharmaceutical industry experience in research, translational sciences, scientific operations, portfolio management, or program leadership roles. Demonstrated experience supporting cross-functional R D programs spanning discovery, preclinical, translational, and/or early clinical development. Proven ability to manage complex integrated program plans, timelines, risks, budgets, and governance processes. Strong scientific acumen with the ability to interpret and communicate complex biological and translational datasets. Excellent written and verbal communication skills, including preparation of executive-level presentations and scientific materials. Strong organizational, collaboration, and influencing skills with the ability to work effectively across matrixed teams. Ability to thrive in a fast-paced, evolving biotech environment with a high degree of ownership and accountability. Preferred Qualifications Direct experience in immunology, immuno-oncology, biologics, or related therapeutic areas. Experience supporting R D governance, portfolio review committees, or executive decision-making forums. Familiarity with translational biomarkers, flow cytometry, immune profiling, and translational data interpretation. Experience in small or mid-sized biotech environments with demonstrated ability to build scalable, fit-for-purpose operational processes. Formal project/program management training, PMP certification, MBA, or equivalent portfolio management experience is a plus. ModeX Therapeutics is an Equal Opportunity Employer Company ModeX Therapeutics is a clinical-stage biopharmaceutical company developing innovative multispecific biologics for cancer and infectious disease. Its platforms unite the power of multiple biologics in a single molecule to create multispecific antibodies and vaccines with unprecedented versatility and potency in fighting complex disease. The ModeX pipeline includes candidates against both solid and liquid tumors, as well as several of the world's most pressing viral threats. Its founding team includes globally recognized medical innovators with proven track records of delivering breakthroughs for patients. ModeX is an OPKO Health company based in Weston, Massachusetts.

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//www.modextherapeutics.com/ Phone (857) 233-9936 Location 20 Riverside Road Weston Massachusetts 02493 United States Share this job Facebook Twitter LinkedIn Apply now Send job Apply now Save job Click to add the job to your shortlist You need to sign in or create an account to save a job. Get job alerts Create a job alert and receive personalized job recommendations straight to your inbox. Create alert