Downstream Process Scientist - Large Scale Development Operations

Company DescriptionEurofins Scientific is an international life sciences company, providing a unique range of analytical testing services to clients across multiple industries, to make life and our environment safer, healthier and more sustainable. From the food you eat, to the water you drink, to the medicines you rely on, Eurofins works with the biggest companies in the world to ensure the products they supply are safe, their ingredients are authentic and labelling is accurate.

Eurofins is the global leader in food, environment, pharmaceutical and cosmetic product testing and in agroscience Contract Research Organisation services. Eurofins is one of the market leaders in certain testing and laboratory services for genomics, discovery pharmacology, forensics, advanced material sciences and in the support of clinical studies, as well as having an emerging global presence in Contract Development and Manufacturing Organisations. The Group also has a rapidly developing presence in highly specialised and molecular clinical diagnostic testing and in-vitro diagnostic products.

In over just 30 years, Eurofins has grown from one laboratory in Nantes, France to 55,000 staff across a decentralised and entrepreneurial network of 900 laboratories in over 50 countries. Eurofins offers a portfolio of over 200,000 analytical methods to evaluate the safety, identity, composition, authenticity, origin, traceability and purity of biological substances and products.

Job DescriptionThe candidate for this position will work as a member of a small team to perform scale-up/scale-down development of therapeutic biologics with strong emphasis on API proteins within the Large-Scale Development & Operations downstream (DSP) group in Malvern, PA. The candidate's primary responsibilities will include a component of pilot-scale DSP operations execution, DSP data acquisition and modeling, and optimizing the process steps to be representative of the target process scale to ensure right first time technical transfers.

This will include:

Pilot-scale and occasional laboratory work with chromatographic purification and several types of filtration systemsRecord and analyze data, verify data integrity and accuracy, and report/summarize findings to the project development teamsDesign experiments to optimize DSP operations within the Large-Scale Development & Operations DSP group to ensure that they are representative of internal and external manufacturing sitesDraft technical documents, SOPs, and work instructionsWork in a team environment as well as contributing individually to meet project timelines and objectivesQualificationsMinimum of BS in scientific related discipline is required.

Knowledge of and hands-on experience with DSP purification (chromatography, filtration) of protein therapeutics (such as antibodies) is required.

Experience with scale-up/down of DSP, and/or execution at pilot or manufacturing scales for biologics manufacture is preferred.

Exposure to analytical method development for in-process methods is preferred.

The candidate must be highly organized and capable of managing/pursuing multiple projects with some supervision.

Experience maintaining written records of work in the form of (electronic) notebooks, technical reports and protocols is preferred.

Data reporting, ability to present findings to management, and experience with team-based collaborations is required.

Additional InformationPosition is full-time, Mon-Fri 9am-5pm. Candidates currently living within a commutable distance of Malvern, PA are encouraged to apply. Excellent full time benefits including comprehensive medical coverage, dental, and vision optionsLife and disability insurance401(k) with company matchPaid vacation and holidays Eurofins USA PSS Insourcing Solutions is a Disabled and Veteran Equal Employment Opportunity employer.