USA-Scientist III (Scientific)

USA-Scientist III (Scientific)#26-09717 Swiftwater, PA All On-site Job Description

Job Description:

Years of Experience:

2 - 6 Years The Downstream Process Development, MSAT department supports several projects including: Seasonal strain changes for Flublok/Covid Vaccine Process improvement and optimization projects Yield improvement strategies and implementation Process monitoring and control Manufacturing support for production operations

Responsibilities:

Primary responsibilities are the execution of development studies such as resin reuse, process improvements, optimization, scale-up, column load, and evaluation of yield improvement strategies as outlined by the Deputy Director

DSP/MSAT

in collaboration with others on projects. Executes purification experiments including automated or high-throughput chromatography (AKTA platform), filtration, clarification/ depth filtration, column packing, and tangential flow filtration independently based on expert knowledge of protein purification and analysis with an in-depth understanding of all modes of chromatography. Makes detailed observations, analyzes data, and interprets results. Exercise technical discretion in the design, execution, and interpretation of experiments that contribute to projects. Prepares technical reports, summaries, protocols, and quantitative analyses. Responsible for training on, understanding, and following documented procedures that apply to their departments. Responsible for general lab maintenance. Qualifications Bachelor's or Master's in Biology, Biomedical, Biotechnology, Biochemistry, or similar discipline Operating, maintaining, and troubleshooting chromatography workstations and process skids Analyzing Data with Assay (SDS PAGE and Western Blot, SRID, BCA, Purity, Dialysis for rBV, ELISA, etc.) Knowledge and experience working with automated high throughput process development equipment Demonstrates working knowledge of scientific principles and concerns Participates in quality control tracking systems including change controls, deviations, CAPA, root cause analysis, etc. Maintains project timelines Good documentation practices (GDP). Experience in writing standard operating procedures (SOP), batch records, and reports Hands-on experience with molecular modeling software is desirable but not required. Proactively anticipates and effectively communicates successes, constraints, solutions, and actions for resolution Fosters relationships with partners, experts from other functions, and customers to achieve technical objectives Perform troubleshooting as required, and supports staff Demonstrate and promote company values and competencies through daily actions and decisions Contribute to strategic planning for downstream process development initiatives Competencies Fluent in English (written and verbal communication) Good communication and interpersonal skills Excellent team member spirit Proficiency in Microsoft Office Suite including Word, Excel, PowerPoint)