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Postdoctoral Associate - Traverso Lab

Job

Broad Institute

Cambridge, MA (In Person)

Full-Time

Posted 2 weeks ago (Updated 1 week ago) • Actively hiring

Expires 5/28/2026

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Job Description

We are seeking a highly motivated Postdoctoral Associate to join an interdisciplinary research team at the Broad Institute , working at the interface of biomaterials, drug delivery, and cell-based therapeutics. The position is embedded within a collaborative environment spanning the Broad Institute, MIT, and affiliated hospitals, with a strong emphasis on translational science and clinically impactful technologies. Research Focus The successful candidate will lead and contribute to projects focused on: Macro-encapsulation systems for cell therapies, including hydrogel-based and implantable platforms Design and synthesis of novel polymers for the delivery of nucleic acids (e.g., m
RNA, DNA
) Development of polymer-lipid hybrid nanoparticles and advanced biomaterials Integration of delivery systems into implantable or ingestible devices Preclinical evaluation of therapeutic systems in relevant in vivo models This work builds on ongoing efforts in cell therapy, gene delivery, and next-generation biomaterials platforms Key Responsibilities Design and synthesize novel polymeric materials for nucleic acid delivery Develop macro-encapsulation platforms for cell-based therapies Conduct in vivo studies in rodent models (e.g., biodistribution, efficacy, safety) Perform in vitro characterization, including cell culture, 3D models, and mechanistic studies Collaborate across disciplines, including engineering, biology, and clinical teams Contribute to high-impact publications, grant writing, and translation efforts Required Qualifications 0+ years of post-graduate experience PhD in Biomedical Engineering, Pharmaceutical Sciences, Materials Science, or related field Strong background in drug delivery, biomaterials, or nanomedicine Demonstrated expertise in: Polymer synthesis and characterization Nucleic acid delivery systems (e.g., LNPs, polymeric carriers) Cell encapsulation or hydrogel systems Hands-on experience with in vivo rodent models, including study design and execution Track record of peer-reviewed publications Preferred Qualifications Experience with macro-encapsulation or implantable devices for cell therapy Familiarity with mRNA delivery, vaccines, or gene therapy platforms Experience with advanced imaging, biodistribution, or disease models (e.g., cancer, CNS) Exposure to translational research or industry collaborations Why Join Work at the cutting edge of biomaterials and therapeutic delivery Access to world-class resources across the Broad Institute, MIT, and Harvard Highly collaborative, fast-paced environment with strong emphasis on real-world impact Opportunities for career development, mentorship, and entrepreneurship

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