Sr. Manager, Global Tax

PTC Therapeutics is a global commercial biopharmaceutical company. For over 25 years our team has been deeply committed to a unified purpose: Extending life's moments for children and adults living with a rare disease. At PTC, we cultivate an inclusive culture where everyone feels valued, respected, and empowered. We welcome candidates from all backgrounds to join our team, fostering a strong sense of belonging. Visit our website to learn more about our company and culture!

Site:

www.ptcbio.com

Job Description Summary:

The Global Tax Senior Manager is responsible for managing the day-to-day direct and indirect tax compliance, reporting, and planning activities across PTC Therapeutics' U.S. and international operations, including the International Headquarters in Ireland and more than 20 international affiliates. This role coordinates global tax deliverables with internal stakeholders and outsourced service providers, supports

U.S. GAAP/ASC 740

reporting and SEC disclosures, oversees U.S. and local country tax compliance, and helps identify and mitigate global tax risks (including VAT/Sales & Use Tax, transfer pricing, and evolving international reporting requirements such as OECD Pillar 2 and country-by-country reporting). The incumbent ensures adherence to relevant regulatory requirements and company SOPs as appropriate.

Job Description:

Responsibilities:

Global Income Tax Compliance & Reporting Manage preparation, review, and filing of U.S. Federal, state, foreign income tax and informational returns, as well as local statutory tax returns and estimated payments for across all entities. Partner with external tax advisors to deliver accurate, timely tax filings and required supporting documentation across jurisdictions. Support international expansion by providing tax compliance and reporting input for the formation of new subsidiaries and entry into new jurisdictions. Tax Provision / U.S.

GAAP / SEC

Reporting (ASC 740) Manage the overall preparation of quarterly and annual tax provisions prepared by third-party service providers in accordance with ASC 740. Assist the Head of Tax in calculating, reviewing, and booking international and U.S. tax charges quarterly and annually. Prepare and/or coordinate tax disclosures for SEC reporting (tax footnotes/disclosures within Forms 10-Q and 10-K), including related support schedules. Complete and review tax payable and tax account reconciliation schedules for U.S. and international entities; manage periodic reconciliations of tax general ledger accounts. Indirect Tax (VAT and U.S. Sales & Use Tax) Oversee internal and outsourced preparation, review, and filing of VAT returns and related documentation; reconcile VAT tax accounts quarterly and proactively manage VAT risk. Assist with preparation of U.S. sales and use tax returns; work cross-functionally to determine correct taxability of transactions. Support vendor setup processes and manage exemption/resale documentation to ensure correct taxation treatment. Support customer inquiries, including assistance with sales tax refund claims and other customer-related indirect tax issues. Transfer Pricing & International Reporting Manage the annual transfer pricing documentation process for international subsidiaries and coordinate with internal stakeholders and external advisors. Establish and maintain international tax reports required under OECD Pillar 2 and country-by-country reporting obligations, as applicable. Audit, Controls, and Governance Manage tax-related requests from external auditors relating to U.S. and international tax filings and provisions. Assist with tax audits and inquiries as needed. Assist in the ongoing review, documentation, and maintenance of tax policies and internal controls in accordance with SOX 404. Other Tax / Projects Maintain fixed asset tax ledger in Oracle (or successor system) and coordinate related tax depreciation reporting. Assist with annual R D and Orphan Drug Credit calculations. Support employment tax compliance matters and ensure compliant reporting. Review and ensure accurate share plan-related tax filings/returns in relevant jurisdictions. Partner with Finance, Legal, Treasury, Supply Chain, and other stakeholders to assess tax implications of business activities and mitigate tax risks. Support special projects and planning initiatives as assigned by the Head of Tax.

Qualifications:

Bachelor's Degree in Accounting, Finance, or related business discipline. Master's degree or Law Degree preferred Minimum of 5 years of progressively responsible experience in tax and/or accounting, ideally in a multinational environment; life sciences/pharma/biotech experience preferred.

Technical / Functional

Strong knowledge of U.S. tax compliance and ASC 740 tax accounting; working knowledge of international tax compliance and reporting (including

IFRS/IAS

tax concepts a plus). Experience managing third-party tax service providers across multiple jurisdictions. Understanding of VAT and/or U.S. Sales & Use Tax compliance and related risk management. Transfer pricing documentation coordination experience preferred. Proficiency with Microsoft Office (advanced Excel skills preferred); experience with major ERP systems such as SAP. Core Competencies Excellent verbal and written communication skills; ability to work effectively with internal and external stakeholders in a matrixed environment. Strong analytical and problem-solving skills with critical attention to detail. Proven ability to manage multiple priorities, meet deadlines, and operate with minimal supervision. Strong planning, organization, and project management capabilities. Proactive, self-motivated, and able to adapt to changing priorities in a fast-paced environment.

TRAVEL REQUIREMENTS

Up to 10% Hybrid position based in

Warren, NJ Expected Base Salary Range:

$140,000 - $160,000. The base salary offered will be contingent on assessment of candidate education level, background, and experience relative to the requirements of the position they are being considered for, as well as review of internal equity. In addition to base salary, PTC employees are also eligible for short- and long-term incentives. All eligible employees may also enroll in PTC's medical, dental, vision, and retirement savings plans.

EEO Statement:

PTC Therapeutics is an equal opportunity employer. We welcome applications from all individuals, regardless of race, color, national origin, gender, age, physical characteristics, social origin, disability, religion, family status, pregnancy, sexual orientation, gender identity, gender expression, disability, veteran status or any unlawful criterion under applicable law. We are committed to treating all applicants fairly and avoiding discrimination. Click here to return to the careers page About Us PTC Therapeutics is a global biopharmaceutical company dedicated to the discovery, development and commercialization of clinically differentiated medicines for children and adults living with rare disorders. PTC is advancing a robust and diversified pipeline of transformative medicines as part of its mission to provide access to best-in-class treatments for patients with unmet medical needs. Our strategy is to leverage our scientific expertise and global commercial infrastructure to optimize value for patients and other stakeholders. To learn more about PTC, please visit www.ptcbio.com and follow us on LinkedIn, X, Instagram and Facebook. Please Beware of False Job Advertisements PTC Therapeutics is aware of employment hiring scams that make false use of our company, leader and employee names to defraud job seekers. PTC does not make job offers without interviews and we never ask candidates for money. If you have encountered a job posting or been approached with a job offer from an email address that does not use ptcbio.com, or that you feel may be fraudulent, we strongly encourage you NOT to respond.