MS Scientist Lab Manager IV

MS Scientist

• Lab Manager IV Health Sciences Core Research Facilities
• Pennsylvania-Pittsburgh
• ( 26003963 ) The University of Pittsburgh is establishing a state-of-the-art, multi-omics facility to support research and clinical translational programs in multiple OMICS disciplines including proteomics, metabolomics, and lipidomics.

We are seeking a highly skilled and motivated Senior Scientist for the Mass Spectrometry Facility to oversee day-to-day operations while remaining actively involved in sample processing and instrument analysis. This role combines leadership, technical expertise, and hands-on execution. The selected candidate will oversee mass spectrometry workflows and coordinate staff while working at the bench to ensure high-quality reproducible data generation. 1. Act as the go-to subject matter expert for mass spectrometry, including custom method development, automation initiatives, and troubleshooting to enhance analytical precision and continuous improvements in mass spectrometry-based omics. 2. Ideal candidate should be able to identify erroneous results and execute rapid fault-diagnosis, root-cause identification, and corrective action on mass spectrometers. 3. Perform hands-on work in all aspects of

LC-MS/MS

workflows, including sample preparation, method development and setup, and data acquisition. 4. Train, mentor, and supervise technical staff; foster a culture of precision, accountability, and teamwork. 5. Collaborate with researchers to design, optimize, and execute mass spectrometry based studies. 6. Ideal candidate should have experience operating, maintaining, calibrating, and troubleshooting mass spectrometers. 7. Maintain accurate records of instrument performance, sample tracking, and results within the Laboratory Information Management System (LIMS). 8. Proven practice in using samples, controls, and standards to create robust reference materials to accurately review and analyze output data. Qualifications

• PhD or Master's degree with 5 years experience in biochemistry, analytical chemistry, or a related field.
• Minimum of 5 years' experience operating and maintaining mass spectrometers.
• Preferably 3 + years in a core facility environment working with Thermo Mass Spectrometry instrumentation, with demostrated experience in method development.
• Proven experience in LC-MS sample preparation, data acquisition, and troubleshooting.
• Demonstrated ability to manage staff and workflow while maintaining personal engagement in laboratory operations.
• Strong organizational, problem-solving, and communication skills.
• A proactive mindset, able to adapt and perform under pressure. Specifically, demonstrate ability to operate in a fast-paced, high-throughput core facility environment.
• Driven and detail-focused scientist who thrives in a collaborative and high-throughput lab environment.

Job Summary Directs day-to-day laboratory operations while ensuring compliance with safety regulations and best practices. Works with, adapts, and installs scientific equipment in research laboratories. Develops complex projects and procedures independently. Manages inventory and equipment and performs budget functions. Writes grant applications and manuscripts independently. Essential Functions The University of Pittsburgh is establishing a state-of-the-art, multi-omics facility to support research and clinical translational programs in multiple OMICS disciplines including proteomics, metabolomics, and lipidomics. We are seeking a highly skilled and motivated Senior Scientist for the Mass Spectrometry Facility to oversee day-to-day operations while remaining actively involved in sample processing and instrument analysis. This role combines leadership, technical expertise, and hands-on execution. The selected candidate will oversee mass spectrometry workflows and coordinate staff while working at the bench to ensure high-quality reproducible data generation. 1. Act as the go-to subject matter expert for mass spectrometry, including custom method development, automation initiatives, and troubleshooting to enhance analytical precision and continuous improvements in mass spectrometry-based omics. 2. Ideal candidate should be able to identify erroneous results and execute rapid fault-diagnosis, root-cause identification, and corrective action on mass spectrometers. 3. Perform hands-on work in all aspects of

LC-MS/MS

workflows, including sample preparation, method development and setup, and data acquisition. 4. Train, mentor, and supervise technical staff; foster a culture of precision, accountability, and teamwork. 5. Collaborate with researchers to design, optimize, and execute mass spectrometry based studies. 6. Ideal candidate should have experience operating, maintaining, calibrating, and troubleshooting mass spectrometers. 7. Maintain accurate records of instrument performance, sample tracking, and results within the Laboratory Information Management System (LIMS). 8. Proven practice in using samples, controls, and standards to create robust reference materials to accurately review and analyze output data. Qualifications

• PhD or Master's degree with 5 years experience in biochemistry, analytical chemistry, or a related field.
• Minimum of 5 years' experience operating and maintaining mass spectrometers.
• Preferably 3 + years in a core facility environment working with Thermo Mass Spectrometry instrumentation, with demostrated experience in method development.
• Proven experience in LC-MS sample preparation, data acquisition, and troubleshooting.
• Demonstrated ability to manage staff and workflow while maintaining personal engagement in laboratory operations.
• Strong organizational, problem-solving, and communication skills.
• A proactive mindset, able to adapt and perform under pressure. Specifically, demonstrate ability to operate in a fast-paced, high-throughput core facility environment.
• Driven and detail-focused scientist who thrives in a collaborative and high-throughput lab environment.

Physical Effort Sitting and standing for long periods, walking around campus to attend meetings. Bending and lifting to put away supplies. Lifting to 30 pounds. Reading small print on tubes, vials and documents. Working in a lab under standard lighting. The University of Pittsburgh is an equal opportunity employer / disability / veteran. Assignment Category Full-time regular Job Classification Staff.

Laboratory Manager IV Job Family Research Job Sub-Family Laboratory Campus Pittsburgh Minimum Education Level Required Bachelor's Degree Minimum Years of Experience Required 7 Will this position accept substitution in lieu of education or experience? Combination of education and relevant experience will be considered in lieu of education and/ or experience requirement. Work Schedule Monday

• Friday, 8:30 a.m.
• 5:00 p.

m., schedule as set with supervisor

Work Arrangement On-Campus:

Teams that work on campus, in an office, or in a lab. Hiring Range TBD Based Upon Qualifications Relocation Offered No Visa Sponsorship Provided No Background Check For position finalists, employment with the University will require successful completion of a background check Child Protection Clearances Not Applicable Required Documents Resume, Cover Letter Optional Documents Not Applicable