Manager, Biosample Operations

At AstraZeneca's Oncology R D division, we follow the science to explore and innovate. We are working towards treating, preventing, modifying, and even curing some of the world's most complex diseases. Here we have the potential to grow our pipeline and positively impact the lives of billions of patients around the world. We are committed to making a difference and have built our business around our passion for science. Now we are fusing data and technology with the latest scientific innovations to achieve the next wave of breakthroughs. Position Summary The Manager, Biosample Operations will lead all aspects of the coordination and tracking of Human Biological Samples (HBS) and information from clinical trial patients across multiple clinical programs. You will work collaboratively within the Translational Sciences team and with teams in accomplishing such goals. This position is based in Santa Monica, CA, and reports to the Director, Translational Operations. Responsibilities Coordinate the logistics and tracking of HBS shipments from the clinical trial sites to the testing laboratories or third-party Contract Research Organizations (CROs). Ensure sample integrity & traceability during transport. Collaborate with the Clinical Operations team and Central Laboratories and other external vendors to troubleshoot any issues occurred while sample collection, processing, storage, or shipment that could affect sample integrity. Help resolve queries in the CRO database. Responsible for receipt, accessioning, and recording of samples sent for laboratory analysis. Manage internal inventory storage and use of clinical samples. Lead all aspects of and track sample analysis by external contractors ensuring that projects are completed and data is generated and transferred according to the agreed timelines. Maintain patient dashboards/scheduling tool(s) used to provide traceability to completion of sample analysis and report generation. Help develop and implement new sample tracking, record-keeping, and quality systems. Support management of inventory storage and usage of reagents for clinical trial assays and assist with procurement tasks. Supervisory Responsibilities May manage contractors. Education and Experience BS with at least 5 years of experience of relevant experience. MS with 4+ years of relevant experience. Excellent record keeping skills. Simultaneously manage work in different clinical programs and prioritize planning of activities. Previous experience managing logistics and storage of bio-specimens from clinical studies. Familiarity with analytical methods and specimen requirements for assays commonly used in data generation for biomarker or pharmacokinetic analysis. Management experience and management of partnered staff at external vendors. Collaborate, work, and organizational interfaces in a dynamic team setting. Experience with LIMS. The anticipated salary range for candidates who will work in Santa Monica, CA is $112,304.00 - $168,456.00. The final salary offered to you will be dependent on several factors that may include but are not limited to the type and length of experience in the job type and length of experience within the industry, education. Benefits Short-term incentive bonus opportunity Equity-based long-term incentive program 401(k) plan Paid vacation and holidays; paid leaves Health benefits including medical, prescription drug, dental, and vision coverage. AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements. When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world Date Posted 24-Apr-2026 Closing Date 03-May-2026 Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form. AstraZeneca is a global, science-led, patient-focused biopharmaceutical company. We focus on discovering, developing and commercialising prescription medicines for some of the world's most serious diseases. But we are more than one of the world's leading pharmaceutical companies. At AstraZeneca, we're dedicated to being a Great Place to Work. Where you are empowered to push the boundaries of science, challenge convention and unleash your entrepreneurial spirit. To embrace differences and take bold actions to drive the change needed to meet global healthcare and sustainability challenges. There is no better place to make a difference in medicine, patients, and society. An inclusive culture where you will connect different thinking to generate new and valuable opportunities. Where you will find a commitment to lifelong learning, growth and development for all. Our Inclusion & Diversity (I&D) mission is to create an inclusive and equitable environment where people belong, using the power of our diversity to push the boundaries of science to deliver life-changing medicines to patients. Inclusion and diversity are fundamental to the success of our company, because innovation requires breakthrough ideas that only come from a diverse workforce empowered to challenge conventional thinking. We're curious about science and the advancement of knowledge. We find creative ways to approach new challenges. We're driven to make the right choices and be accountable for our actions. As an organisation centred around what makes us human, we put a big focus on people. Across our business, we want colleagues to wake up excited about their day at the office, in the field, or in the lab. Along with our purpose to bring life-changing medicines to people across the globe, we have a promise to you: to help you realise the full breadth of your potential. Here, you'll do work that has the potential to change your life and improve countless others. And, together with your team, you'll shape a culture that unites and inspires us every day. This is your life at AstraZeneca.