Clinical Supply Chain Manager

Job Title:

Clinical Supply Chain Manager (Contract-to-Hire) Job Description This role leads end-to-end clinical supply chain activities for a diverse portfolio of small molecule and biologic drug candidates across global development programs. You will drive supply excellence from planning, inventory management, packaging, labeling, and distribution through to study closeout, ensuring timely and reliable delivery of investigational medicinal products to patients worldwide. Partnering closely with Clinical Operations, CMC, Quality, Regulatory, Project teams, and external vendors, you will design and execute supply solutions that optimize speed, quality, and patient-centricity. This full-time, 12-month contract-to-hire position requires an agile, execution-focused leader who can operate in a highly outsourced model and help build infrastructure and processes as one of the earliest members of the clinical supply chain team. Responsibilities Lead end-to-end clinical supply strategy and execution for global clinical programs from study startup through closeout. Develop agile and scalable clinical supply strategies that adapt to enrollment variability, program priorities, and operational requirements. Proactively identify risks and develop mitigation strategies using data and scenario planning to optimize supply continuity. Translate clinical protocols into robust demand forecasts and supply plans that support global clinical trials. Manage end-to-end clinical supply activities, including packaging, labeling, inventory management, distribution, depot setup, returns, and reconciliation. Optimize inventory to maximize product utilization and minimize waste due to expiry or retest dates. Ensure seamless global distribution through integrated supply planning and execution frameworks. Serve as the subject matter expert for drug supply within

IRT/RTSM

implementation and operations. Drive adoption of automation and AI-enabled tools to streamline workflows and enhance supply visibility. Support implementation of scalable technologies and future planning tools that improve operational efficiency and oversight. Lead operational governance with CDMOs, CROs, depots, and logistics providers in a fully outsourced execution model. Establish performance metrics and conduct data-driven business reviews to improve service delivery and accountability with external partners. Oversee CDMOs to ensure supply continuity and execution against forecasts, escalating issues as needed. Ensure compliance with GMP, GCP, ICH, FDA, EMA, and other applicable global regulatory frameworks. Partner with Quality to manage deviations, CAPAs, change controls, and product complaints, applying risk-based approaches to maintain compliance. Take internal ownership of temperature excursions and product complaints, coordinating responses and corrective actions. Drive alignment across Clinical Operations, CMC, Quality, Regulatory, Project teams, and external partners on supply strategies and execution. Communicate supply risks, status, and mitigation strategies through clear, actionable reporting and transparent communication. Influence cross-functional decision-making by providing data-driven insights, scenario analyses, and strategic recommendations. Forecast drug supply and demand using advanced Excel capabilities, managing inventory and forecasting datasets efficiently. Work effectively within Google Workspace and other digital collaboration tools to support cross-functional coordination. Support comparator sourcing and management for global clinical trials, including complex and rare disease/oncology studies. Contribute to building clinical supply chain infrastructure, processes, and best practices as one of the earliest members of the team. Participate in or support future implementation of planning tools and other digital solutions aligned with an AI and automation-focused direction. Essential Skills 8+ years of clinical supply chain experience in biotech or pharmaceutical settings, with the majority focused on clinical supply chain. Demonstrated experience managing clinical supply chains for small molecule and biologic products across all development phases. Proven ability to translate clinical protocols into demand forecasts and supply plans for global clinical trials. Strong understanding of supply forecasting, inventory strategy, and end-to-end clinical supply chain processes. Hands-on experience managing packaging, labeling, distribution, depot setup, returns, and reconciliation for clinical supplies. Experience on the sponsor side managing external vendors, including CDMOs and other supply chain partners. Proven experience in comparator sourcing and management for global clinical trials. Experience with

IRT/RTSM

systems (such as IQVIA, Medidata, or similar), with platform-agnostic, transferable skills. Strong vendor management skills, including oversight of CDMOs and logistics providers to ensure supply continuity. Ability to identify risks early and drive supply decisions across CMC, manufacturing, and clinical teams. Advanced Excel skills, including pivot tables, formulas, and data analytics for forecasting and inventory management. Comfort working within Google Workspace or similar collaboration platforms. Working knowledge of GMP, GCP, ICH, FDA, EMA, and global regulatory requirements related to clinical supplies. Experience managing temperature excursions and product complaints within a quality and regulatory framework. Bachelor's degree in Life Sciences, Business, Supply Chain, or a related discipline. Strong communication skills, with the ability to drive alignment, escalate issues appropriately, and maintain transparency across stakeholders. Proven project and program management capabilities within clinical supply chain environments. Additional Skills & Qualifications Advanced degree in a relevant discipline is preferred but not required. Experience in rare disease, oncology, biologics, and other complex clinical trial settings. Experience with fully outsourced execution models where CDMOs handle manufacturing, logistics, and distribution, and the internal team manages oversight and escalation. Background in purchasing, procurement, customer service, and contract negotiation within a supply chain context. Exposure to or interest in AI and automation tools, with a willingness to leverage new technologies to improve operations. Potential exposure to planning tools implementation and other digital supply chain solutions. Agile and proactive working style, with comfort operating in an environment with limited infrastructure. High ownership mentality and a strong sense of accountability for outcomes. Ability to build strong relationships across teams and external partners. Passionate, curious, and trainable mindset, with enthusiasm for continuous improvement and innovation. Work Environment This is a full-time, 40-hour-per-week, 12-month contract-to-hire role. The position supports a highly outsourced clinical supply chain model in which external CDMOs manage manufacturing, logistics, and distribution, while the internal team focuses on oversight, governance, and issue escalation. The role is open to candidates working remotely within Pacific or Mountain time zones, with a preference for individuals who can occasionally be on-site and collaborate in person with the broader CMC and Clinical Supply Chain teams. You will report into the clinical supply chain function, which sits within the CMC organization, and you will be the second member of a growing clinical supply chain team, offering significant opportunity to shape processes, infrastructure, and ways of working. The organization heavily leverages AI and automation tools and anticipates future implementation of advanced planning technologies, creating a modern, data-driven environment. Lunch is provided onsite, and the culture emphasizes collaboration, transparency, and high ownership in support of complex oncology and rare disease programs. Job Type & Location This is a Contract position based out of South San Francisco, CA. Pay and Benefits The pay range for this position is $65.00 - $85.00/hr. Eligibility requirements apply to some benefits and may depend on your job classification and length of employment. Benefits are subject to change and may be subject to specific elections, plan, or program terms. If eligible, the benefits available for this temporary role may include the following:

• Medical, dental & vision
• Critical Illness, Accident, and Hospital
• 401(k) Retirement Plan - Pre-tax and Roth post-tax contributions available
• Life Insurance (Voluntary Life & AD&D for the employee and dependents)
• Short and long-term disability
• Health Spending Account (HSA)
• Transportation benefits
• Employee Assistance Program
• Time Off/Leave (PTO, Vacation or Sick Leave) Workplace Type This is a fully remote position.

Application Deadline This position is anticipated to close on Jun 19, 2026. About Actalent Actalent is a global leader in engineering and sciences services and talent solutions. We help visionary companies advance their engineering and science initiatives through access to specialized experts who drive scale, innovation and speed to market. With a network of almost 20,000 consultants and 5,000 clients across the U.S., Canada, Asia and Europe, Actalent serves many of the Fortune 500. We are proud to be an Engineering News-Record (ENR) Top 500 Design Firm for our engineering design services and a ClearlyRated Best of Staffing® winner for both client and talent service. The company is an equal opportunity employer and will consider all applications without regard to race, sex, age, color, religion, national origin, veteran status, disability, sexual orientation, gender identity, genetic information or any characteristic protected by law. If you would like to request a reasonable accommodation, such as the modification or adjustment of the job application process or interviewing process due to a disability, please email actalentaccommodation@actalentservices.com for other accommodation options.

San Francisco Fair Chance Ordinance:

Pursuant to the San Francisco Fair Chance Ordinance, for all positions located in the city and county of San Francisco, we will consider for employment qualified applicants with arrest and conviction records.

Massachusetts Lie Detector:

It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability. Use of Artificial Intelligence (AI): We may use Artificial Intelligence (AI) to support parts of our hiring process, including sourcing, screening, and evaluating candidates. AI helps assess applications and qualifications, but final decisions are made by our hiring team. By applying, you acknowledge and agree that your application may be reviewed using AI tools.