Research Technician - MCPHS

The School of Arts & Sciences seeks a part-time Research Technician to support studies investigating extracellular vesicles (EVs) as biomarkers and mediators of development and disease. The position will involve processing human and rodent biological samples, isolating and characterizing EVs using the current MISEV guidelines, and developing novel approaches for identifying unique EV populations in blood. Prior experience with EVs is preferred but not required. Candidates with experience in plasma/serum biomarker studies, immunoprecipitation, western blotting, flow cytometry, and/or other molecular biology techniques are encouraged to apply. This is a temporary part-time position expected to work 18-25 hours per week. Research (85%) Perform laboratory procedures including extracellular vesicle (EV) isolation and characterization, western blotting, immunoprecipitation, RNA extraction and RT-PCR, flow cytometry, and other molecular biology techniques in support of ongoing research projects. Assist with the development, validation, optimization, and troubleshooting of laboratory assays and procedures. Prepare various solutions and/or media accordingly and develop recipes based on concentrations of ingredients. Organize, and maintain experimental data, laboratory records, and sample inventories in accordance with laboratory and institutional standards. Maintain laboratory equipment and ensure compliance with laboratory safety procedures and applicable institutional, state, and federal regulations. Training & Professional Development (15%) Assist the Principal Investigator in the supervision of undergraduate and graduate students to ensure good laboratory practice, scientific rigor, and safe engagement in meritorious research projects. Develop and teach laboratory protocols. Participate in scientific dissemination activities, including manuscript preparation, conference abstracts, and presentations, with opportunities for authorship based on substantive research contributions. Additional responsibilities may be assigned by the supervisor, including the possibility of participating in animal research projects (mice and rats).

Required:

Bachelor's degree in Molecular Biology, Biomedical Sciences, or a closely related field. Demonstrated expertise in molecular biology techniques such as western blotting, RNA extraction, and/or immunoprecipitation, with a minimum of 1-year hands on experience obtained through academic research, employment, internships, or equivalent training. Ability to maintain accurate documentation and work independently, as well as collaboratively, in a research environment. Strong organizational, analytical, and problem-solving skills with attention to detail. Ability to use good judgment in managing deadlines. Excellent verbal and written communication skills, including ability to effectively communicate.

Preferred:

Prior experience working with extracellular vesicles (EVs), RNA, or related biomarker research. High proficiency with molecular biology techniques such as western blotting, RNA extraction, and immunoprecipitation techniques.

Physical Requirements:

Remaining in a normal seated or standing position for extended periods of time. Reaching and grasping by extending hand(s) or arm(s); dexterity to manipulate objects with fingers, for example, using a keyboard or pipetting multiple biological samples for extended periods of time. Ability to move about workspace and crawl under desks. Must be able to lift and carry up to 50 lbs. Ability to see and hear within normal parameters. Must be able to talk, listen and speak clearly on a telephone.