Senior Vice President, Human Resources

Job Title:

Senior Vice President, Human Resources Location:

San Diego, California Job Type:

Full-Time Who We Are Avenzo Therapeutics, Inc. ( Avenzo or Company ) is a clinical-stage biotechnology company focused on developing next-generation oncology therapies for patients. The Company was co-founded in 2022 by Drs. Athena Countouriotis and Mohammad Hirmand (former CEO and CMO of Turning Point Therapeutics, Inc., respectively). Our team is passionate about and committed to advancing a pipeline of potential best-in-class targeted oncology programs that make a difference in the lives of people with cancer. The Company is headquartered in San Diego, California. Position Summary Reporting to the CEO, the Senior Vice President, Human Resources is responsible for developing and executing HR strategies that support and align with the company s overall business plan and strategic direction. The candidate will oversee all core HR functions, including talent acquisition, talent management, total rewards (compensation and benefits), employee engagement, HR operations (HRIS, budgeting), compliance, and employee relations. The candidate will also serve as a strategic advisor to the CEO, executive team, and Board of Directors. Essential Job Functions and Responsibilities Lead the development and implementation of long-range HR strategies and practices that align with and support the company s business objectives Partner with the CEO and senior leadership team on overall organizational strategy and workforce planning to drive company growth Serve as trusted advisor to the CEO and Board of Directors to ensure strategic alignment between the company s business strategy and talent strategy; partner with the CEO and the Compensation Committee of the Board to establish compensation and equity frameworks that align with performance and market competitiveness Establish scalable processes and programs to effectively recruit, onboard, develop, retain, and reward top quality talent at all levels across the organization Develop a comprehensive total rewards philosophy that links compensation, benefits and employee development to the company s mission and values while driving engagement, retention and performance Partner with Finance on workforce planning, budgeting and headcount forecasting Build and optimize HR systems, processes, and analytics to support decision-making and operational efficiency Partner with the Legal team to ensure compliance with all applicable employment laws and regulations, manage workplace investigations, and drive policy governance Direct and mentor a high-performing HR team, fostering collaboration, innovation, and operational excellence Preferred Qualifications Bachelor s degree in Human Resources, Business Administration or a related area degree preferred (e.g., MBA) with 20+ years of progressive HR leadership experience in the life sciences industry or an equivalent combination of academic and industry experience Proven experience partnering with CEOs, senior leadership teams and Boards to shape strategy, culture and organizational effectiveness Demonstrated track record of building and scaling HR functions to support organizational growth (pre- and post-IPO experience preferred) Strong business acumen with the ability to influence at the executive level Collaborative with a proven ability to cultivate a high-performance culture across the organization Excellent communication and interpersonal skills, with the ability to collaborate effectively with internal and external stakeholders Strong analytical and problem-solving abilities, with a strategic mindset This position requires periodic/regular travel, including up to 10% of work time, which may include overnight travel

Physical Demands and Work Environment Physical Demands:

Constant or continuous use of a computer keyboard, monitor, and mouse to perform a variety of tasks Constant or frequent sitting, standing, or walking May lift and/or move objects of various weights

Work Environment:

San Diego-based:

On-site requirement (Monday through Thursday) Noise level in the work environment is usually moderate Fast-paced, time sensitive environment with frequently changing priorities Handle multiple projects simultaneously Reasonable accommodations may be provided to enable qualified individuals with disabilities to perform the essential functions of the position. Salary Range The salary range for this position is $371,000 to $397,000 per year. The final pay offered to a successful candidate will be dependent on several factors that may include, but are not limited to, the type and years of experience within the job and the industry, education, and skills and certifications. Benefits Provided they meet all eligibility requirements under the applicable plan documents, employees (and their eligible dependents) will be eligible to enroll in group healthcare plans that offer medical, dental, vision, and basic life and AD&D insurance. Additional benefit programs include short-term and long-term disability insurance, flexible spending accounts, health savings accounts, and voluntary insurance programs, including voluntary life, AD&D accident, and critical illness. Employees will also be able to enroll in the Company s 401(k) plan. In addition, employees will receive discretionary paid vacation time and accrue 1 hour of paid sick leave for every 30 hours worked. Employees also enjoy 17 paid holidays each calendar year, including a winter closure, subject to applicable Company policies. All benefits are subject to the terms and conditions of the applicable plan documents and Company policies, which may be amended from time to time. Other Compensation The hired candidate will be eligible to receive an annual discretionary bonus and an equity award, subject to the terms of the applicable employment agreement, plan documents, and Company policies. The information above is intended to provide a general description of benefits and other compensation and is not a substitute for applicable plan documents or company policies. Applications for this position are anticipated to close on June 30, 2026. For more information about this posting, please contact careers@avenzotx.com . Equal Employment Opportunity Avenzo is committed to providing equal employment opportunities to all employees and applicants without regard to an individual s actual or perceived protected characteristic or characteristics, or any combination of protected characteristics including race (including traits associated with race, such as hair texture and protective hairstyles, including braids, locks, and twists), ethnicity, religion, religious creed (including religious dress and grooming practices), color, sex (including childbirth, breast feeding, and related medical conditions), gender, gender identity or expression, sexual orientation, national origin, ancestry, citizenship status, uniformed service member and veteran status, marital status, pregnancy, age (40 and over), protected medical condition (including cancer and genetic conditions), genetic information, disability (mental and physical), reproductive health decision-making, medical leave or other types of protected leave (requesting or approved for leave under the Family and Medical Leave Act or the California Family Rights Act), the employee or their family member s status as a victim of a qualifying act of violence, political activity or affiliation, use of cannabis off the job and away from the workplace, association with an individual who has, or is perceived to have, a protected characteristic or characteristics, or any combination of protected characteristics, or any other protected status in accordance with all applicable federal, state, and local laws. Notice to Search Firms/Third Party Agencies Avenzo does not accept unsolicited resumes from recruiters, employment agencies or search firms without a valid, executed search agreement in place.