Sr. Director, Nonclinical Safety & Portfolio Strategy

Sr. Director, Nonclinical Safety & Portfolio Strategy Employer AbbVie Location North Chicago, IL Salary 206500 - 393000 USD Start date May 19, 2026 View more categories View less categories Discipline Administration , Clinical , Manufacturing & Production Required Education Doctorate/PHD/MD Position Type Full time Hotbed BioMidwest , Best Places to Work Apply now Save job Click to add the job to your shortlist You need to sign in or create an account to save a job. Send job Job Details Company Job Details Company Description About AbbVie AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com . Follow @abbvie on LinkedIn, Facebook , Instagram , X and YouTube.

Job Description Description:

AbbVies Development Biological Sciences department is seeking a Senior Director for its Portfolio Leadership Group. This pivotal leadership role will serve as a nonclinical safety representative for assigned molecules across AbbVies diverse portfolio. As a safety representative, the Senior Director will be responsible for the overall strategy and execution of the nonclinical toxicology program, collaborating cross-functionally with project leads, providing data interpretation at various internal and external venues, and authoring regulatory documents. The ideal candidate will have 15+ years of experience in the area of non-clinical safety within the pharmaceutical industry. He/she should have the experience and ability to develop drug candidates from discovery through marketing. This senior-level position is expected to have a high impact contributing scientific expertise in nonclinical safety assessment, knowledge of industry best practices and pertinent regulatory guidelines, and a vision of future enhancements in the field.

Responsibilities:

Drive the strategic vision and direction for nonclinical safety, influencing key R D and portfolio decisions at the organizational level. Serve as an active member for multi-disciplinary project teams as a nonclinical safety functional area subject matter expert. Articulate and communicate non-clinical safety strategies and provide development plans for multiple drug modalities including but not limited to small molecules, biologics, ADCs, and/or cell and gene therapies, across various therapeutic areas including but not limited to oncology, neuroscience, and immunology. Participate in due diligence reviews of drug products to identify potential risks and provide recommendations for partnership or in-licensing. Author and submit regulatory documents (IBs, INDs/CTAs, NDAs/BLAs, regulatory queries) and interact with regulatory agencies (US and ex-US) as needed. Generate impurity, excipient and metabolite risk assessments as necessary during the life cycle of a drug candidate. Lead, mentor and develop others as it pertains to drug development and the execution of the portfolio, with an emphasis on the nonclinical aspects. Participation in pharmaceutical industry consortia related to nonclinical aspects of drug development. Qualifications PhD or DVM required. 15+ years of relevant experience in pharmaceutical industry leading nonclinical safety programs. Experience authoring relevant regulatory documents and responding to requests from regulatory agencies. Deep expertise in a particular therapeutic area or modality (e.g. immunology, gene therapy, etc) is a benefit, but not required. General awareness and understanding of drug metabolism and pharmacokinetics and its interplay with safety (e.g. MIST, drug-drug interactions, toxicokinetics, anti-drug antibodies...) is a plus. Skilled in project/program management and leadership. General computer skills and knowledge of the Microsoft applications including but not limited to Microsoft Word, Excel, and PowerPoint and applying AI as appropriate and necessary. Additional Information Applicable only to applicants applying to a position in any location with pay disclosure requirements under state orlocal law: The compensation range described below is the range of possible base pay compensation that the Companybelieves ingood faith it will pay for this role at the timeof this postingbased on the job grade for this position.

Individualcompensation paid within this range will depend on many factors including geographic location, andwemayultimatelypaymore orless than the posted range. This range may bemodifiedin thefuture. We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick),medical/dental/visioninsurance and 401(k) to eligibleemployees. This job is eligible toparticipatein our short-term incentiveprograms.

Note:

No amount of payis considered to bewages or compensation until such amount is earned, vested, anddeterminable.

The amount and availability of any bonus,commission,incentive, benefits, or any other form ofcompensation and benefitsthat are allocable to a particular employeeremainsin the Company's sole andabsolutediscretion unless and until paidandmay bemodifiedat the Companys sole and absolute discretion, consistent withapplicable law. AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled. US & Puerto Rico only - to learn more, visit https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more: https://www.abbvie.com/join-us/reasonable-accommodations.html Company AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com . Follow @abbvie on LinkedIn, Facebook , Instagram , X and YouTube.

Company info Website http:

//www.abbvie.com/ Phone 1-800-255-5162 Location 1 North Waukegan Road North Chicago Illinois 60064 United States Share this job Facebook Twitter LinkedIn Apply now Send job Apply now Save job Click to add the job to your shortlist You need to sign in or create an account to save a job. Get job alerts Create a job alert and receive personalized job recommendations straight to your inbox. Create alert