Principal Scientist Process Chemistry

Principal Scientist - Process Chemistry Coventry, RI Summary We are seeking an experienced and collaborative Principal Scientist to lead complex chemical development programs within a fast-paced Process Chemistry environment. This role provides scientific leadership across multidisciplinary project teams, supporting API development for GLP toxicology studies and GMP clinical manufacturing while delivering high-quality solutions to clients. The successful candidate will combine strong technical expertise in synthetic/process chemistry with leadership, mentoring, and client-facing responsibilities. Key Responsibilities Lead and design experimental programs to solve complex chemical development challenges for client projects and internal initiatives. Apply advanced process chemistry and retrosynthetic analysis expertise to support API development and process optimization. Plan, execute, document, and report experimental work in compliance with applicable GxP, ICH, GMP, and company standards. Serve as a scientific leader and mentor to junior scientists and cross-functional project teams. Manage and support multiple client projects, including project leadership, reporting, technical discussions, and delivery of project milestones. Support technology transfer activities and mixed-model projects across the organization. Build strong client relationships, host client visits, and support internal and external audits. Stay current with emerging scientific technologies and apply innovative approaches to process chemistry challenges. Promote a strong quality culture, collaboration, safety, and continuous improvement within the department. Maintain accurate training records and ensure compliance with all safety, procedural, and environmental requirements. Qualifications Required PhD in Chemistry or related scientific discipline OR MSc/BSc in Chemistry or related field with significant relevant industry experience Experience & Technical Skills Strong academic and/or industrial achievements in process chemistry or chemical development Demonstrated experience solving complex chemical development problems Expertise in retrosynthetic analysis and advanced laboratory techniques/instrumentation Experience supporting API drug development within regulated environments Proven ability to contribute effectively within multidisciplinary scientific teams Prior team leadership or people management experience preferred Experience working within GMP and/or GLP environments strongly preferred Key Competencies Strong scientific leadership and mentoring capabilities Excellent organizational and project management skills Strong written and verbal communication abilities Exceptional attention to detail and problem-solving skills Ability to manage multiple priorities in a fast-paced environment Collaborative mindset with strong client-facing professionalism Solid computer and technical documentation skills Compensation ranges depending on Associate or Principal requirements: Principal Scientist $140k -$170k Associate Principal Scientist $130k -$160k Additional Information This role requires strict adherence to company policies, SOPs, environmental health and safety procedures, and confidentiality standards. The successful candidate will help foster a transparent, collaborative, and quality-driven culture focused on delivering high-quality products and services while maintaining the highest professional and ethical standards.