Research Associate II

Jobs › Waltham, MA › Research Associate II Adecco US, Inc. Research Associate II Waltham, MA Apply Adecco Healthcare & Life Sciences is hiring a Research Associate II for our Scientific partner in Waltham, MA. The anticipated hourly wage for this position is $54.38. Hourly wage may depend upon experience, education, geographic location, and other factors. Benefit offerings include medical, dental, vision, life insurance, short-term disability, additional voluntary benefits, EAP program, commuter benefits, Daily Pay, and 401K plan. Our program provides employees the flexibility to choose the type of coverage that meets their individual needs. Available paid leave may include Paid Sick Leave, where required by law; any other paid leave required by Federal, State, or local law; and Holiday pay upon meeting eligibility criteria.

Must-have skills:

• Purification experience/ Protein purification chromatography
• Critical thinking
• Strong communication
• Professional industry experience is required for bachelor's and master's degree level candidates.
• AKTA must have
• Filtra ration
• Must have protein purification AV experience, to have
• Bachelor's degree with a minimum of 2 years min of relevant experience
• Master's degree with a minimum of 0+ years, will only consider in school experience only for MS Candidates
• No PHD candidates, overqualified.

Nice to have skills:

• DOE/ Design of Experiments a plus
• BSL Biosafety Lab Level II experience a plus

Job Description Description:

Position Overview/Department Description:

The Genomic Medicine Unit (GMU) is responsible for the design and optimization of viral vector manufacturing processes and platforms. This organization encompasses vector and cell line engineering, upstream and downstream process development, analytics, and clinical manufacturing support. The GMU purification process development group is responsible for the development of AAV and non-viral vector processes and for supporting viral vector purification from next-generation production platforms to enable high-dose gene therapy programs. The Senior Research Associate (SRA) - Downstream Process Development role requires leadership both inside and outside the laboratory and will rely on industry expertise and the exploration of novel technologies in order to build robust and efficient purification processes consistent with patient safety standards. We are looking for a candidate with experience in AAV and/or non-viral purification development, scale-up and manufacturing, and technology transfer.

Key Responsibilities:

• Support to develop, design and conduct viral vector purification experiments and evaluate new technologies to increase product yield and process understanding
• Develop, maintain and demonstrate advanced knowledge of principals and techniques in column chromatography and other areas of downstream purification
• Maintain industry knowledge and awareness of new and relevant technologies, and be willing to publish findings and to speak both internally and externally as industry leaders
• Lead / support development of study design, optimization of purification process conditions, media screening and perform troubleshooting experiments and communicate findings with appropriate working groups
• Perform data analyses, contribute to technical reports and internal/external presentations
• Support scale-up activities to implement a manufacturing process based on applied DSP knowledge
• Communicate effectively with internal and external teams, e.g. CDMOs for tech transfer activities
• Contribute to manuscript and patent writing for external publications and patent applications, respectively
• Self-motivated and display sound technical judgement
• Build a culture of support and collaboration among colleagues Basic Qualifications
• Master's degree in biological sciences or related discipline, or Bachelor's degree with a minimum of 2 years of relevant experience
• Experience, knowledge and understanding of purification technologies and operations such as: o Depth filtration o AKTA or automated protein purification chromatography o Tangential flow filtration or UF/DF o Virus clearance and inactivation o Filtration unit operations at various scales o Strong grasp of chromatography principles and modalities o Experience with process technology transfers and performing gap analyses and risk assessments o Expertise in technical report writing o Ability to learn and perform viral vector analyses using new tools and techniques o Exhibits good laboratory practices including writing neat laboratory procedures in lab notebooks Preferred Qualifications • Familiarity with purification of viral vectors • Knowledge of basic analytical tools such as spectrophotometry, ELISA, HPLC, and

SDS-PAGE

• Basic understanding of the principles of Quality by Design and ability to apply DOE to downstream development
• Understanding of viral clearance study design and execution strategy preferred
• Experience with large-scale unit operations
• Ability to work in Biosafety Level 2, follow safe lab procedures and maintain good laboratory practices (GLPs)
• Ability to work under minimal supervision and function within a collaborative, team-oriented environment
• Excellent organization and communication skills
• Ability to build and nurture cross-functional relationships
• Ability to communicate and represent group in diverse, multi-functional meetings
• Ability to stand and work with lab bench equipment in laboratory

Pay Details:

$54.38 per hour Benefit offerings available for our associates include medical, dental, vision, life insurance, short-term disability, additional voluntary benefits, EAP program, commuter benefits and a 401K plan. Our benefit offerings provide employees the flexibility to choose the type of coverage that meets their individual needs. In addition, our associates may be eligible for paid leave including Paid Sick Leave or any other paid leave required by Federal, State, or local law, as well as Holiday pay where applicable. Equal Opportunity Employer/Veterans/Disabled Military connected talent encouraged to apply To read our Candidate Privacy Information Statement, which explains how we will use your information, please navigate to https://www.adecco.com/en-us/candidate-privacy The Company will consider qualified applicants with arrest and conviction records in accordance with federal, state, and local laws and/or security clearance requirements, including, as applicable: The California Fair Chance Act Los Angeles City Fair Chance Ordinance Los Angeles County Fair Chance Ordinance for

Employers San Francisco Fair Chance Ordinance Massachusetts Candidates Only:

It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability. Active Filters Research Associate II Waltham, MA Clear All Apply