Senior Principal Scientist, Tech Ops (CMC Science) - Recombinant

Senior Principal Scientist, Tech Ops (CMC Science) - Recombinant Employer CSL Location King of Prussia, PA Start date May 22, 2026 View more categories View less categories Discipline Information Technology , Applications/Technical Support , Science/R D , Biotechnology , CMC Required Education Masters Degree/MBA Position Type Full time Hotbed Pharm Country , Best Places to Work Apply now Save job Click to add the job to your shortlist You need to sign in or create an account to save a job. Send job Job Details Company Job Details S enior Principal Scientist, TechOps (CMC Science) - Recombinant This role is Global and can be based in Bern, CH, Marburg DE, King od Prussia, PA USA or Kankakee IL USA Job Purpose The Senior Principal Scientist is a recognized technical expert within the Recombinant Integrated Product Team (IPT), providing advanced scientific expertise and leading complex technical activities to support product lifecycle management. The role contributes to the execution of product strategies by delivering high-quality scientific input, leading defined technical initiatives, and supporting cross-functional decision-making to ensure robust product performance and continuous improvement. Main Responsibilities & Accountabilities 1. Technical Expertise and Workstream Leadership Acts as a subject matter expert in recombinant process science, providing advanced technical knowledge to support complex product-related activities. Leads defined technical workstreams or projects within broader product initiatives. Delivers high-quality scientific outcomes in line with project objectives, timelines, and performance expectations. 2. Contribution to Product Strategy and Planning Contributes technical input to the development and refinement of the product technical roadmap. Identifies and evaluates improvement opportunities (e.g., process robustness, yield, compliance) and supports their assessment and implementation. Provides scientific input into business cases and supports data-driven decision-making processes. 3. Cross-Functional Collaboration Works within a global, matrixed IPT environment, collaborating with Manufacturing, MS&T, Quality, and Regulatory functions. Supports alignment of technical activities across sites and functions. Engages with stakeholders to ensure effective execution of product-related initiatives. 4. Scientific Oversight and Technical Support Ensures application of sound scientific principles and compliance in product lifecycle activities, including process changes and technology transfers. Provides input to technical decision-making processes, including change controls, validation strategies, and lifecycle management activities. Supports data analysis, process understanding, and technical risk assessments. 5. Continuous Improvement and Innovation Contributes to the identification and implementation of process improvements and efficiency gains. Applies scientific methodologies and data analysis to improve process consistency and product quality. Supports implementation of best practices and innovative approaches within the IPT. 6. Stakeholder Interaction and Communication Communicates complex technical information clearly to cross-functional stakeholders. Contributes to technical discussions and governance forums as required. Builds effective working relationships to support delivery of product objectives. 7. Coaching and Knowledge Sharing Provides guidance and informal mentoring to junior scientists and team members. Contributes to knowledge sharing and continuous development of technical capabilities within the organization. Qualifications & Experience Requirements PhD in Biochemistry, Biotechnology, Chemical Engineering, or related Life Sciences discipline. Typically 8-12 years of relevant experience in biopharmaceutical development and/or manufacturing within a GMP environment. Strong expertise in recombinant product process development, manufacturing, and lifecycle management. Experience contributing to complex technical projects in a matrix environment. Solid understanding of process validation, technology transfer, and regulatory requirements. Demonstrates strong project management skills, including planning, coordination, and execution of multiple projects to ensure timely delivery of objectives. About CSL Behring CSL Behring is a global biotherapeutics leader driven by our promise to save lives. Focused on serving patients' needs by using the latest technologies, we discover, develop and deliver innovative therapies for people living with conditions in the immunology, hematology, cardiovascular and metabolic, respiratory, and transplant therapeutic areas. We use three strategic scientific platforms of plasma fractionation, recombinant protein technology, and cell and gene therapy to support continued innovation and continually refine ways in which products can address unmet medical needs and help patients lead full lives. CSL Behring operates one of the world's largest plasma collection networks, CSL Plasma. Our parent company, CSL, headquartered in Melbourne, Australia, employs 32,000 people, and delivers its lifesaving therapies to people in more than 100 countries. To learn more about

CSL, CSL

Behring, CSL Seqirus and CSL Vifor visit https://www.csl.com/ and CSL Plasma at https://www.cslplasma.com/ . Our Benefits For more information on CSL benefits visit How CSL Supports Your Well-being | CSL . You Belong at CSL At CSL, Inclusion and Belonging is at the core of our mission and who we are. It fuels our innovation day in and day out. By celebrating our differences and creating a culture of curiosity and empathy, we are able to better understand and connect with our patients and donors, foster strong relationships with our stakeholders, and sustain a diverse workforce that will move our company and industry into the future. To learn more about inclusion and belonging visit https://www.csl.com/careers/inclusion-and-belonging Equal Opportunity Employer CSL is an Equal Opportunity Employer. If you are an individual with a disability and need a reasonable accommodation for any part of the application process, please visit https://www.csl.com/accessibility-statement . Company CSL is a global biotechnology company with a dynamic portfolio of lifesaving medicines, including those that treat hemophilia and immune deficiencies, vaccines to prevent influenza, and therapies in iron deficiency and nephrology. Since our start in 1916, we have been driven by our promise to save lives using the latest technologies. Today, CSL - including our three businesses, CSL Behring, CSL Seqirus and CSL Vifor - provides lifesaving products to patients in more than 100 countries and employs 32,000 people. Areas of Expertise We focus and demonstrate global leadership in three distinct areas—rare and serious diseases; influenza vaccines; and iron deficiency and nephrology. Rare & Serious Diseases CSL Behring is a global biotherapeutics leader driven by our promise to save lives. Focused on serving patients' needs by using the latest technologies, we discover, develop and deliver innovative therapies for people living with conditions in the immunology, hematology, cardiovascular and metabolic, respiratory, and transplant therapeutic areas. Vaccines As one of the largest influenza vaccine providers in the world, CSL Seqirus is a major contributor to the prevention of influenza globally and a transcontinental partner in pandemic preparedness. CSL Seqirus utilizes egg, cell and adjuvant technologies to offer a broad portfolio of differentiated influenza vaccines in more than 20 countries. Iron Deficiency & Nephrology With our iron deficiency and iron deficiency anemia expertise in heart failure, kidney disease, gastroenterology or inflammatory bowel disease, patient blood management and women's health, we help patients affected by these conditions to live better, healthier lives. Company info Phone 610-878-4000 Location 1020 First Avenue King of Prussia Pennsylvania 19406 United States Share this job Facebook Twitter LinkedIn Apply now Send job Apply now Save job Click to add the job to your shortlist You need to sign in or create an account to save a job. Get job alerts Create a job alert and receive personalized job recommendations straight to your inbox. Create alert