GMP Downstream Purification Chemist

Mission The Downstream Purification Chemist will be responsible for handling all peptide purification techniques under cGMP requirements and be accountable managing all phases of their assigned projects from concept through to release, ensure adequate prioritization, proper documentation and timely execution of the projects. This individual will work closely with GMP Synthesis, QC, and other areas in production. General Responsibilities Performs GMP large scale peptide purification using reverse phase HPLC methodology. Performs non-GMP large scale peptide purification using reverse phase HPLC methodology. Adhere to GMP BPR and follow in-process control identified in the BPR. Analyze and troubleshoot methods and data obtained from GMP and large-scale Research grade (non-=GMP) projects. Recommends alternatives and suggestions to improve processes, validity and/or accuracy of downstream methods. Maintains and troubleshoots instruments, equipment and general lab areas if needed. Maintains detailed records of results which may include collecting, extracting and entering data via both electronic and paper files (i.e., notebooks, logbooks, batch records, etc.) Manage resources according to project priorities. Assist is purification method development practices such as during engineering runs, feasibility or pilot runs. Train and assist team members. Create an environment knowledge-sharing so everyone on the team learns and grows with the Company. Produce and maintain good written documentation of GMP projects. Follows protocols, SOPs, and batch production records while adhering to good documentation practices (GDP). Manipulates, interprets and/or presents results; prepares charts and graphs for presentations and publications as needed. Tracks and summarizes lab supply expenses; orders and maintains inventory of reagents, lab supplies and consumables and requests quotes for external vendors and verify accuracy of invoices. Work closely with Quality Assurance and Quality Control and other departments to ensure that product meets and/or exceeds specification requirements. Ensure implementation, compliance, and continuous improvement of QMS through SOP documentation. Other duties as assigned by Management. Job Requirements Bachelors in chemistry, organic chemistry, biochemistry or equivalent experience. Excellent oral and written communication skills Able to lift, push and pull 40 lbs Strong peptide purification and analysis background Work experience biotech/life science industry environment preferred Experience working in a global atmosphere is a plus Must be organized and detail oriented GMP experience a plus Writing technical SOPs, Batch Production Records (BPR) and technical reports Proficient in computer skills (MS Office, data analysis, ChemDraw, others). • AnaSpec, Inc. is an equal opportunity employer offering a competitive compensation and benefits package including medical, dental, vision, flexible spending accounts, life insurance, short-term & long-term disability, 401(k), and other benefits!

Pay:

$75,000.00 - $80,000.00 per year

Benefits:

401(k) Dental insurance Flexible spending account Health insurance Life insurance Paid time off Vision insurance

Work Location:

In person