Senior Scientist - Disease Modeling & Translational Biology (C9orf72-ALS/FTD)

Senior Scientist - Disease Modeling & Translational Biology (C9orf72-ALS/FTD) Corsalex, Inc. Sunnyvale, CA Job Details Full-time $140,000 - $165,000 a year 3 days ago Benefits Health insurance Dental insurance 401(k) Paid time off 401(k) matching Qualifications Biology Research design Stem cell culture Western blot Molecular Biology Teamwork Doctoral degree Neuroscience Laboratory experiments Neurobiology Assay development Cell Biology Molecular cloning Supervising experience Doctor of Philosophy Team management Decision making Mentoring Data interpretation Experimental design Laboratory staff supervision Senior level Full Job Description About Corsalex Corsalex is a discovery-stage biotech in Sunnyvale, CA building a portfolio of programs targeting C9orf72-driven amyotrophic lateral sclerosis and frontotemporal dementia. We operate as a small, technically dense team running multiple programs in parallel. We move at the pace of a small biotech and seek high autonomy, fast iteration, and direct lines from hypothesis to data to decision.

Note:

To apply for this role please email a resume and cover letter to and include Corsalex Scientist Position_Your Full Name in the email subject line. The Role We're hiring a Senior Scientist to own biology and disease modelling end-to-end across our

C9-ALS/FTD

portfolio. This is a hands-on bench role based in Sunnyvale, CA with full project ownership: you design and run the experiments, interpret the data, and shape program direction. You'll work directly with our management team and mentor a junior scientist on the bench. This role suits a wet-lab biologist who's done a postdoc, is familiar with the C9 literature, and is ready to take ownership of program development. Responsibilities Design, execute, and interpret experiments in C9-ALS/FTD-relevant cellular models, including iPSC-derived systems. Lead one or more discovery programs end-to-end, from target or mechanism hypothesis through assay development, compound or modality testing, and go/no-go decisions. Develop and validate cellular assays for target engagement. Mentor a junior scientist; set lab operations and workflow standards across the team. Synthesize internal and external data into clear scientific arguments, written and verbal, that drive program decisions. Identify gaps, propose new approaches, and drive them forward. Clearly communicate timelines, deliverables, and lab outputs. Qualifications PhD in Cell Biology, Neurobiology, Molecular Biology, or a related discipline, plus postdoc in a neuroscience lab. Strong experience in ALS/FTD biology and relevant cellular model systems; direct

C9-ALS/FTD

experience is strongly preferred. Hands-on expertise with iPSC-derived neuronal differentiation, characterization, and phenotypic assay development. Proficiency in molecular cloning, lentiviral vector construction, and standard biochemistry (Western blot, IP, basic protein work). Demonstrated ability to operate independently, to scope a problem, design the experiments, troubleshoot, and reach defensible conclusions without close oversight. Experience mentoring or directly supervising junior scientists or technicians. What We Look For You take initiative and don't wait to be told what to do. You're comfortable working alone but value collaboration and reaching out when you need to. You speak up, even (especially) when you disagree. You're curious and want to understand how things actually work. Low ego, high ownership. You're adaptable when programs shift or priorities change. You're organized, communicative, reliable, and committed to high-quality science. Benefits The base salary offered will be contingent on candidate's background and experience Equity All eligible employees may also enroll in medical, dental, and retirement savings plans Applicants must be authorized to work for any employer in the U.S. We are unable to sponsor or take over sponsorship of an employment visa at this time. To apply for this role please email a resume and cover letter to and include Corsalex Scientist Position_Your Full Name in the email subject line.

Location:

Sunnyvale, CA. On-site.

Pay:

$140,000.00 - $165,000.00 per year

Benefits:

401(k) 401(k) matching Dental insurance Health insurance Paid time off

Education:

Doctorate (Required)

Work Location:

In person