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Job Description
More Results Postdoctoral Associate, Mammalian Synthetic Biology Employer Massachusetts Institute of Technology Location North Cambridge, Massachusetts, US Salary Competitive Closing date Jun 21, 2026 View more categories View less categories Sector Academic / Research Field Conservation science Discipline Statistics , Biology Job Level Post doctoral fellow Salary Type Salary Employment Type Full time Apply on website Save job Click to add the job to your shortlist You need to sign in or create an account to save a job. Send job
, Biological Engineering - Weiss Lab (http://weiss-lab.mit.edu/) , t o join an interdisciplinary academic research lab focused on creating integrated biological systems capable of autonomously performing useful tasks and elucidating design principles for engineering complex cellular and tissue phenotypes; d esign, build, and test mammalian synthetic gene circuits, including sensing modules (e.g., RNA/miRNA/metabolite-responsive elements), logic/control elements, and output programs that drive measurable cellular behaviors; engineer and maintain mammalian cell lines; p erform genome engineering and targeted integration workflows; v alidate engineered lines using standard molecular and cellular assays; and p lan and execute experiments to characterize circuit performance using flow cytometry, microscopy, RT-qPCR, sequencing-based readouts, ELISA, and related methods. Job Requirements
REQUIRED
Ph.D. in biological sciences, computer science, engineering, physics, math, or a related field; experience in a minimum of the following-mammalian cell culture and differentiation, iPSC engineering, large-scale DNA assembly and characterization, genetic recombination and site-specific genome integration (e.g., CRISPR/Cas9, RMCE), next-generation sequencing, computational methods/tools for analysis, and statistics; background in molecular biology, synthetic biology, protein engineering, immunology, and/or cell biology; demonstrated ability to design and execute rigorous experiments and detailed protocols; strong organizational, analytical, problem-solving, and documentation skills; ability to manage multiple priorities and work both independently and collaboratively in a dynamic, multidisciplinary environment; and excellent written and verbal communication skills, including presenting research through talks and publications.
PREFERRED
Experience designing and validating mammalian genetic circuits that sense cell state (e.g., mRNA/miRNA) and/or use recombinase- or CRISPR-based control strategies; proficiency in common characterization methods (e.g., flow cytometry, RT-qPCR, NGS-based readouts); and experience working in milestone-driven, team-based research programs and contributing to manuscripts, reports, and sponsor-facing presentations.4/14/2026 Share this job Facebook Twitter LinkedIn Apply on website Send job Apply on website Save job Click to add the job to your shortlist You need to sign in or create an account to save a job. Get job alerts Create a job alert and receive personalized job recommendations straight to your inbox. Create alert
