Post-Doctoral Associate: GI Division, Liang Lab

Post-Doctoral Associate:

GI Division, Liang Lab University of Minnesota - 4.1 Minneapolis, MN Job Details Full-time 1 day ago Qualifications Biology research Dissection Publishing papers in peer-reviewed journals Animal blood collection Molecular biology techniques IV insertion In vivo studies Manuscripts for peer-reviewed journals Laboratory research Laboratory animal handling Assays Full Job Description Required Qualifications Recent Ph.D. or M.D./Ph.D. with a strong background in cancer biology, molecular biology, or related fields. Excellent in in-vivo gene editing, including applying and developing next generation gene editing technologies, such as prime editing, base editing, and recombinases Excellent technical skills for mouse in-vivo work comprising but not limited to IV injections, retro-orbital bleeding, necropsy. Knowledge and experience in advanced in vivo techniques such as liver perfusion and hepatocyte isolation, intratracheal injection, lung function assays. Evidence of a publication record in relevant peer-reviewed journals. Highly motivated candidates are encouraged to apply. Fluency in one programming languages is a plus but not required (Python, R/Matlab). A postdoctoral position is available in Dr. Shunqing Liang's laboratory at the University of Minnesota Twin Cities, Department of Medicine in the Division of Gastroenterology, Hepatology, & Nutrition. Our laboratory is dedicated to applying the CRISPR-mediated genome-editing techniques for Gene Therapy and Cancer Research. Our long-term goal is to harness the capabilities of CRISPR to develop precise and targeted genome-editing strategies tailored to the challenges of lung and liver disease. This innovative approach holds promise for unlocking new avenues in gene therapy, cancer research, and immunotherapy. The individuals will use CRISPR techniques to characterize cancer-associated mutations and identify neoantigens related to lung cancer and liver cancer. They will also learn experimental approaches and methods to investigate the pathogenic impact of aberrant mutations on tumorigenesis and biology. They will participate in collaborative projects and present their work at national and international conferences. We employ multidisciplinary approaches, including genetic engineered mouse models, CRISPR screens, Prime editors, Protein engineering, AAVs, LNP, single-cell RNA sequencing, FACS, Immunohistochemistry, and Next generation sequence. Additional information on our research projects can be found in our recent publications, including Nature Methods, Nature Biotechnology, Nature Communications, Cancer Research, EMBO molecular medicine, & Oncogene. Applications must be submitted online. To be considered for this position, please click the Apply button and follow the instructions. You will be given the opportunity to complete an online application for the position and attach a cover letter and resume. Additional documents may be attached after application by accessing your "My Job Applications" page and uploading documents in the "My Cover Letters and Attachments" section. To request an accommodation during the application process, please e-mail or call (612) 624-8647. The University recognizes and values the importance of diversity and inclusion in enriching the employment experience of its employees and in supporting the academic mission. The University is committed to attracting and retaining employees with varying identities and backgrounds. The University of Minnesota provides equal access to and opportunity in its programs, facilities, and employment without regard to race, color, creed, religion, national origin, gender, age, marital status, disability, public assistance status, veteran status, sexual orientation, gender identity, or gender expression. To learn more about diversity at the

U:

http://diversity.umn.edu Any offer of employment is contingent upon the successful completion of a background check. Our presumption is that prospective employees are eligible to work here. Criminal convictions do not automatically disqualify finalists from employment. The University of Minnesota, Twin Cities (UMTC) The University of Minnesota, Twin Cities (UMTC), is among the largest public research universities in the country, offering undergraduate, graduate, and professional students a multitude of opportunities for study and research. Located at the heart of one of the nation's most vibrant, diverse metropolitan communities, students on the campuses in Minneapolis and St. Paul benefit from extensive partnerships with world-renowned health centers, international corporations, government agencies, and arts, nonprofit, and public service organizations. At the University of Minnesota, we are proud to be recognized by Forbes as a Best Employer for Company Culture (2026), Best Employer for Women (2023), and Best Employer by State (2022-2026). In 2026, we also received Culture Excellence & Industry Awards recognition for employee appreciation and work-life flexibility.