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Associate Principal Scientist, Regenerative Immunology
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InVitro Cell Research, LLC
Englewood, NJ (In Person)
$187,500 Salary, Full-Time
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Job Description
Associate Principal Scientist, Regenerative Immunology Employer InVitro Cell Research, LLC Location Englewood, NJ Start date Jun 1, 2026 View more categories View less categories Discipline Science/R D , Biotechnology , Immunology Required Education Masters Degree/MBA Position Type Full time Hotbed Pharm Country Apply now Save job Click to add the job to your shortlist You need to sign in or create an account to save a job. Send job Job Details Company Job Details ICR's Regenerative Immunology program is focused on regenerating the aging immune system, the decline of which underlies many of the most devastating age-related diseases. We're hiring a Principal Scientist to lead our Thymic Regeneration Team to restore thymic function and rejuvenate adaptive immunity. You'll need a deep background in immunology, thymic biology and iPSCs. With ICR, you'll get to: Lead a cutting-edge team developing iPSC-derived thymic epithelial cells (iTECs) and thymic organoids to rejuvenate the aging immune system Contribute highly practical and readily translatable thymic regeneration, immune reconstitution and rejuvenative medicine ideas Design and optimize directed-differentiation protocols to generate functional, TECs from human iPSCs Collaborate with other ICR scientists and groups to advance immune rejuvenation under a personalized medicine paradigm Please apply if you have: A PhD or MD/PhD At least 10 years of research experience, preferably in thymic biology, stem cell differentiation, organoid engineering or regenerative immunology Current and in-depth knowledge of thymic epithelial cell biology, iPSC directed differentiation, T-cell development and tissue engineering Expert knowledge in experimental therapeutics and the landscape of developmental pipelines of practical, actionable interventions to treat and prevent age-related immune senescence and achieve immune regeneration/rejuvenation Ideally, you'll also have: Expert knowledge of thymic epithelial cell ontogeny, FOXN1 biology, T-cell selection and thymic niche reconstitution Experience with iPSC culture, directed differentiation, 3D organoid culture, single-cell genomics, RNAseq, flow cytometry, immunofluorescent microscopy, CRISPR gene editing and cell culture Experience with in vivo transplantation, humanized mouse models and assessment of functional immune reconstitution Even if you don't meet all of these criteria, please apply anyway And you'll need: A friendly, easygoing personality The ability to work in the United States without sponsorship Salary Starting base pay range: $160,000/yr - $215,000/yr Starting additional compensation range: $10,000/yr - $20,000/yr Starting position title and compensation are commensurate with experience. Company InVitro Cell Research, LLC (ICR) is a privately funded company focused on regenerative and preventive personalized medicine. We are dedicated to discovering and developing interventions to slow and reverse biological aging and prevent major age-related diseases. ICR has a small-group vibe and a highly collaborative work environment. We invest in our scientists, providing them the state-of-the-art resources they need to leverage their time and skills most effectively, empowering small teams to accomplish the amazing and advance our mission. Our mission is to research ways to repair aging people, fast.