Research Principal, UPMC

The Seney Lab (https://seneylab.pitt.edu) in the Translational Neuroscience Program and Department of Psychiatry at the University of Pittsburgh is seeking a highly motivated Research Principal to join an interdisciplinary research team studying the molecular and systems-level biology of psychiatric and substance use disorders. Our lab integrates large-scale omics data with behavioral phenotypes to understand mechanisms underlying brain disorders and to identify novel therapeutic targets. This position offers the opportunity to work on cutting-edge, data-intensive projects in a collaborative environment alongside neuroscientists and computational researchers. Join a collaborative and supportive research lab at a top-tier research institution where we offer opportunities for professional development, authorship, and conference presentations. This position is grant funded.

Responsibilities:

Analyze and interpret high-dimensional biological data, including transcriptomic (e.g., bulk and single-cell RNA-seq), epigenetic, and proteomic datasets Develop, implement, and maintain statistical and computational analysis pipelines Apply rigorous statistical methods to experimental design, hypothesis testing, and data interpretation Collaborate closely with experimental scientists to translate biological questions into analytic strategies Contribute to manuscript preparation and data visualization Document workflows and ensure reproducibility of analyses