Post-Doctoral Research Associate: Department of Biochemistry & Cellular and Molecular Biology - UTK

Post-Doctoral Research Associate:

Department of Biochemistry & Cellular and Molecular Biology - UTK Knoxville, TN Job Details Full-time $56,956 a year 1 day ago Qualifications Research design Proteomics Electrophoresis Laboratory instruments Scientific publications Laboratory experiments Doctor of Philosophy Experimental design Mass spectrometers (MS) Senior level AI Liquid chromatography machines Full Job Description The Sun lab ( https://www.jiesunlab.com/ ) is interested in developing advanced mass spectrometry-based structural proteomics platforms to investigate protein structure and dynamics in native environments.

We focus on:

(1) integral membrane proteins embedded in their physiological lipid contexts, and (2) intrinsically disordered proteins such as Tau. By integrating chemical footprinting, in situ labeling strategies, and multi-modal MS analysis, we aim to decode the high-order structures of those sensitive proteins and facilitate the understanding of disease mechanisms and drug development. The Sun lab is in the BCMB department (bcmb.utk.edu) at the University of Tennessee in the city of Knoxville. This is a grant-funded position and is contingent upon the continued funding of the grant. This postdoctoral position is expected to work largely on a recently NIH-funded project in the area of mass spectrometry-based protein biophysics of membrane proteins. The main experimental techniques for investigations will include mass spectrometry (MS), protein footprinting, cross-linking, protein MS imaging, and AI-based protein structural prediction. The main instrument would be a newly installed TimsTOF Pro 2 coupled with NanoElute 2 nanoHPLC-MS system in the Sun laboratory. Required Qualifications Ph.D. in mass spectrometry-based proteomics, mass spectrometry imaging, or a related field. First-author publication(s) in peer-reviewed journals. Strong background in protein biochemistry or molecular biology. Ability to design and conduct independent research experiments. Preferred Qualifications and Skills Experience in protein expression and purification. Experience with SDS-PAGE, Western blotting, and standard protein characterization techniques. Experience with protein footprinting, cross-linking MS, or structural proteomics.

Work Location Location:

University of Tennessee, Knoxville Onsite Compensation and Benefits Anticipated hiring range: $56,956 Application Instructions For full consideration, interested individuals should provide a cover letter addressing professional experience relevant to each required minimum qualification and a resume. Screening of applicants will begin immediately and will continue until the position has been filled.

About The Department:

The University of Tennessee Department of Biochemistry & Cellular and Molecular Biology (BCMB) is home to over 400 undergraduate majors. Housed in the Ken and Blaire Mossman (1311 Cumberland Ave.) and Hesler Biology and Greenhouse (1406 Circle Dr.) Buildings, our research teams of faculty, undergrads, graduate students, and postdoctoral fellows are working on topics ranging from molecular structure to organismal levels.