SPR Specialist

Job Title:

SPR Specialist Annual Base Salary:

DOE, $87,000-$115,000 along with bonus eligibility and a comprehensive benefits package

Location:

Los Angeles, CA Our Mission Formerly known as the Ellison Institute of Technology Los Angeles, the Ellison Medical Institute strives to spark innovation, leverage technology, and drive interdisciplinary, patient-centered research to continually enhance health, reimagine and redefine cancer care, and transform lives. Established in 2016 as a medical research and development center, the Institute features innovation labs for artificial intelligence and molecular analytics and was among the first organizations to vertically integrate the interdisciplinary study and treatment of disease. We offer multifaceted programs, including a preventative medicine and cancer clinic, cross-disciplinary research laboratories, a health policy think-tank, and community outreach and educational programs. Please visit emila.org for more details. Job Summary The Ellison Medical Institute is seeking a Specialist in Biophysical Characterization with strong expertise in Surface Plasmon Resonance (SPR) to support and advance peptide and protein discovery programs. This individual will independently design, execute, and interpret SPR-based binding and kinetic studies, including assay development, ligand immobilization strategy selection, and data modeling. The role will also contribute to peptide and protein production activities, including expression, purification, and sample quality assessment, to support high-quality biophysical studies. The successful candidate will work closely with cross-functional discovery teams, provide scientific insight to drive project decisions, and support instrument optimization, troubleshooting, and best-practice development.

Why You Should Join Us:

• Build a New Capability from the

Ground Up:

Establish and scale in-house SPR and biophysical characterization capabilities for peptide and proteins within a growing therapeutic discovery platform. •

Direct Scientific Impact:

Own SPR assay strategy, data quality standards, and biological interpretation, generating decision-enabling data to support drug discovery, lead optimization, and preclinical testing. •

Highly Collaborative Environment:

Partner closely with peptide design, biological evaluation, and analytical teams to translate synthetic peptides and proteins into therapeutic discovery programs.

Job Accountabilities:

•

SPR Assay Development:

Independently design, execute, troubleshoot, and optimize SPR assays using Biacore instruments. •

Data Analysis and Scientific Interpretation:

Analyze and interpret SPR data within the appropriate biological and biophysical context, critically evaluating binding kinetics, fitting models, controls, and experimental assumptions to generate decision-ready data for discovery and lead-selection efforts. •

Cross-Functional Collaboration:

Work closely with design, discovery, analy...