Scientist, Cell Engineering

Scientist, Cell Engineering at RecruitSeq Scientist, Cell Engineering at RecruitSeq in Sonoma, California Posted in 1 day ago.

Type:

full-time

Job Description:

Scientist, Synthetic Immune Cell Engineering SF Bay Area (Mid-Peninsula) Our client is an early-stage biotech startup pioneering a next-generation platform for engineered cell therapies. They are building a proprietary receptor architecture designed to unlock previously inaccessible signaling pathways - enabling any cell type to be precisely programmed for therapeutic effect. About the Role Join the founding scientific team and help generate the core science underpinning a differentiated cell therapy platform. You will lead experimental workstreams end-to-end, from assay development through in vivo validation, working directly with leadership to shape both the research direction and company culture. This is a high-ownership, high-visibility role at a company where your contributions will have direct and lasting impact. Responsibilities Develop and optimize immunological assays (e.g., ELISA, flow cytometry) and functional assays (e.g., proliferation, cytotoxicity) to support platform and program objectives. Validate and characterize novel molecular tools - including synthetic receptors, CRISPR constructs, and RNA-based modalities - in clinically relevant primary cell types. Lead experimental workstreams supporting cell therapy product development from concept through execution. Coordinate in vivo study execution with vivarium staff, including preparation of experimental materials and downstream sample analysis. Translate high-level program goals into detailed experimental plans in close collaboration with scientific leadership. Analyze and interpret multi-dimensional immunological datasets; use coding (e.g., Python) to support routine data analysis and visualization. Mentor junior scientists and research associates; contribute to building a rigorous, collaborative lab culture. Qualifications PhD in immunology, gene editing, bioengineering, or a related field. 2+ years of direct industry experience preferred. 5+ years of hands-on experience with ex vivo immune cell culture and mouse tissue processing. Demonstrated experience developing immune cell-based methods to validate and optimize molecular tools (e.g., CRISPR, synthetic receptors, siRNA). Proficiency in Python or another coding language for data analysis and visualization. Proven track record of independently leading impactful research projects. Strong documentation practices and ability to troubleshoot and resolve technical problems quickly. Excellent written and verbal communication skills across technical and cross-functional audiences.