R&D Scientist, Metabonomics or Lipidomics

Protheragen is seeking a talented and motivated scientist to direct the Metabolomics Platform. The successful candidate will work closely and collaboratively with scientists on a range of academic and industrial projects employing targeted and untargeted metabolomics and lipidomics, as well as introducing cutting edge analytical and mass-spec techniques to solve customers' problems.

Responsibilities:

• Perform LC-MS workflow for metabolomics/lipidomics including sample preparation, method development and execution, method validation, data acquisition and analysis, and report writing;
• Operate and maintain of mass spectrum system including but not limited to

ABI/SCIEX QTRAP 6500

， Thermo Q Exactive Plus, QQQ

• Demonstrate competency in troubleshooting, optimization and implementation of challenging and innovative

LC-MS/MS

assays;

• Adhere to established Standard Operating Procedures and contribute to validation protocols, reports and bioanalytical reports.
• Understanding of metabolomics literature and apply theoretical framework to solving problems

Requirements:

• PhD, MSc or BSc in Biochemistry, Biology, Chemistry or similar Life Science
• Significant experience in targeted metabolomics LC-MS method development, method validation and troubleshooting;
• Familiarity with metabolomics platforms including but not limited to

AB QTRAP 6500, THERMO QE

Plus and QQQ

• Familiarity with metabolite identification and profiling studies;
• Hands-on experience in LC/MS small molecule applications, including method development, quantification, characterization, and structure elucidation.
• Hands-on experience in various biological sample preparation technique such as PP, LLE, and SPE. And
• Hands-on experience and troubleshooting skills on LC separation techniques (i.

e.

RP, HILIC

) and Mass Spec

• Proficiency with mass spectrometry software as well as spreadsheet, word processing, and graphical computer programs;
• Knowledge of LC-MS assay validation guidelines and GLP regulations;

Job Types:

Full-time, Contract Pay:

$100,000.00 - $150,000.00 per year

Benefits:

401(k) matching Health insurance Retirement plan

Work Location:

In person