Senior Clinical Trial Manager

Senior Clinical Trial Manager Employer Nurix Therapeutics Location Brisbane, CA Start date May 15, 2026 View more categories View less categories Discipline Clinical , Clinical Research , Clinical Trials Required Education Bachelors Degree Position Type Full time Hotbed Biotech Bay Apply now Save job Click to add the job to your shortlist You need to sign in or create an account to save a job. Send job Job Details Company Job Details Nurix Therapeutics is a clinical stage biopharmaceutical company focused on the discovery, development, and commercialization of targeted protein degradation medicines, the next frontier in innovative drug design aimed at improving treatment options for patients with cancer and inflammatory diseases. Powered by a fully AI-integrated discovery engine capable of tackling any protein class, and coupled with unparalleled ligase expertise, Nurix's dedicated team has built a formidable advantage in translating the science of targeted protein degradation into clinical advancements. Nurix aims to establish degrader-based treatments at the forefront of patient care, writing medicine's next chapter with a new script to outmatch disease Nurix is seeking a Senior Clinical Trial Manager to join the Clinical Operations team. This individual will be responsible for management of global regions and/or clinical programs. They will lead study team, vendors, clinical monitors and clinical sites throughout the life cycle of a clinical trial. This individual will be able to manage clinical regions or trial(s) and have broad involvement in work central to Nurix's strategic goals. They will apply existing technical skills, learn new skills, and play a key role in clinical development of the programs. As an early hire, they'll be influential in championing and developing Nurix's culture. The Senior Clinical Trial Manager is responsible for the successful implementation of a clinical trial, independently, from start-up to close-out. Experience in managing cross-functional teams, vendor oversight, knowledge of applicable regulatory requirements and developing junior staff will be essential to the team's success. The Sr. CTM will represent Clinical Operations at Project team meetings and may represent Nurix at professional events.

Job Responsibilities:

Accountable for all operational aspects of assigned clinical trial(s) or geographical region. Responsible for selection of vendors/CROs and provide effective ongoing management and oversight to vendors/CROs to ensure compliance and execution of deliverables within the approved budget, study timeline, and study protocol Works closely with investigative site personnel, CROs, and other study vendors Monitor and track clinical trial progress and provide status update to stakeholders Manage study contracting, budget, forecasting, accruals and payment process for all clinical trial vendors including investigational sites Collaborate with Data Management to ensure correct CRFs content is collected, prepare/implement CRF completion guidelines, and coordinate delivery of data updates, listings and study reports Drafts and coordinates review of relevant documents including protocols, informed consents, case report forms, monitoring plans, investigator brochures and clinical study reports. Must be able to participate in cross-functional strategic initiatives under limited supervision Proactively identifies potential issues/risks and recommends/implements solutions Provides leadership to the clinical operations team working on the assigned program

Experience and Skills:

B.S./ B.A.

in biological sciences, advanced degree preferred with 5-10 years of relevant industry experience Ability to travel as required for the program (10-15%) Demonstrated knowledge of FDA, ICH and GCP regulations and guidelines Experience in leading teams, including CROs, consultants and vendors Must display strong analytical and problem-solving skills at a project level and collaborate with colleagues to generate solutions Strong communication and influence skills and ability to create a clear sense of direction Ability to deal with time demands, incomplete information or unexpected events Outstanding organizational skills with the ability to work independently, multi-task and prioritize Comfortable in a fast-paced small company environment and able to adjust workload based upon changing priorities

Salary Range:

172K - 199K plus bonus and equity. Nurix Therapeutics, Inc. is committed to protecting and respecting your privacy and personal information, including information collected by Nurix when you apply for a job with Nurix or in the course of your employment with Nurix. By applying for a position at Nurix, you agree to our collection and use of personal information as described in our Privacy Policy ( https://www.nurixtx.com/privacy-policy/ ). Company Nurix Therapeutics is a biopharmaceutical company focused on the discovery, development and commercialization of small molecule therapies designed to modulate cellular protein levels as a novel treatment approach for cancer and immune disorders. Leveraging Nurix's extensive expertise in E3 ligases together with its proprietary DNA-encoded libraries, Nurix has built DELigase, an integrated discovery platform to identify and advance novel drug candidates targeting E3 ligases, a broad class of enzymes that can modulate proteins within the cell. Nurix's drug discovery approach is to either harness or inhibit the natural function of E3 ligases within the ubiquitin proteasome system to selectively decrease or increase cellular protein levels. Nurix's wholly owned pipeline comprises targeted protein degraders of Bruton's tyrosine kinase, a B-cell signaling protein, and inhibitors of Casitas B-lineage lymphoma proto-oncogene-B, an E3 ligase that regulates T cell activation. Nurix is headquartered in San Francisco, California.

Company info Website https:

//www.nurixtx.com/ Phone 415-660-5320 Location 1700 Owens Street Suite 205 San Francisco California 94158 United States Share this job Facebook Twitter LinkedIn Apply now Send job Apply now Save job Click to add the job to your shortlist You need to sign in or create an account to save a job. Get job alerts Create a job alert and receive personalized job recommendations straight to your inbox. Create alert