Postdoctoral Fellow in Neurology (Wallings Lab)

Title Postdoctoral Fellow in Neurology (Wallings Lab) Specific Title Postdoctoral Fellow in Department of Neurology and Stark Neurosciences Research Institute Appointment Type Postdoctoral Fellow Department IUSM - Neurology Campus IU School of Medicine Indianapolis Position Summary The Wallings Lab at the Indiana University School of Medicine, Department of Neurology and Stark Neurosciences Research Institute, is seeking a highly motivated Postdoctoral Research Fellow to join our research team. Our lab focuses on the role of an aging immune system in neurodegenerative diseases, with a specific focus on immune cell exhaustion and immunosenescence in the peripheral immune system. Our long-term research mission is to leverage such mechanisms to develop more effective immunomodulatory interventions that delay or halt neurodegeneration. We are seeking a highly motivated Postdoctoral Fellow to join our research team to investigate the role of immune cell exhaustion and biological immune aging in the heterogeneity of Parkinson's Disease (PD). This position is supported by a three-year award and focuses on understanding how immune cell exhaustion, familial PD mutations, mitochondrial dysfunction and chronic inflammation intersect to contribute to clinical and pathological heterogeneity in PD. The successful candidate will work at the interface of basic and translational science, leveraging molecular, cellular, and animal model systems as well as patient-derived samples to uncover mechanisms of disease heterogeneity and progression and identify novel therapeutic targets. Primary Duties and Responsibilities Design, execute, and analyze experiments investigating immune cell exhaustion and neuroimmune interactions in the context of PD. Employ cutting-edge approaches including spectral flow cytometry, machine learning and irradiation techniques to generate bone marrow chimera models. Utilize mouse models and patient-derived samples to explore how biological immune aging contributes to heterogeneity in PD and how immune cell exhaustion may contribute to disease onset and progression. Perform statistical analyses, data integration, and interpretation ofplex datasets. Contribute to manuscript preparation, grant writing, and presentation of research findings at meetings and conferences. Collaborate with team members across disciplines and institutes and mentor junior researchers or students when appropriate. Maintain accurate records, ensurepliance with laboratory safety standards, and contribute to a collaborative and innovative lab environment. IU School of Medicine ismitted to being a weing campusmunity and we seek candidates whose research, teaching, andmunity engagement efforts contribute to robust learning and working environments for all students, staff, and faculty. We invite individuals who will join us in our mission to improve health equity and well-being for all throughout the state of Indiana. Indianapolis is the capital and most populous city in the State of Indiana. It is growing economically thanks to a strong corporate base anchored by the life sciences. Indiana is home to one of the nation's largest concentrations of health sciencespanies. Indianapolis has a sophisticated blend of charm and culture with a wonderful balance of business and leisure. The growing residential base is supported by rich amenities and quality of life - the city possesses a variety of professional sports, arts venues, and outdoor recreation areas. Residents of this dynamic city and surrounding suburbs enjoy leading educational systems and top-ranked universities paired with a diverse population. Indianapolis International Airport is a top-ranked international airport that has been named "Best Airport in North America" by Airports Council International for many years. For additional information on life in

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faculty.medicine.iu/relocation Basic Qualifications Educational Requirements Candidates must have an MD/PHD or Ph.D. in Neuroscience, Immunology or a related field prior to the start of the appointment. Skills Requirements Prior experience in neuroimmunology-related research is highly desirable Strong background in flow cytometry, in vivo research in murine models and machine learning Strong background in statistical data analysis Excellentmunication,anizational skills and written skills Ability to work independently and collaboratively Skills Preferences Familiarity with neurodegeneration research and preclinical models of PD Experience with behavioral testing Experience generating bone marrow chimeras via non-lethal doses of irradiation Department for Questions beckwalliu Additional Qualifications Special Instructions Priority Application Review Deadline Expected Start Date 06/01/2026 Posting Number

IUSM-02404-2026

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