Scientist, Theranostics and Radiation Science

Fusion Pharmaceuticals, a member of the AstraZeneca Group, is a clinical-stage oncology company focused on developing next-generation radioconjugates (RCs) as precision medicines. Fusion connects alpha particle emitting isotopes to various targeting molecules to selectively deliver the alpha emitting payloads to tumors. Fusion's clinical portfolio includes but is not limited to:

FPI-2265

targeting prostate specific membrane antigen (PSMA) for metastatic castration resistant prostate cancer currently in a Phase 2 trial;

FPI-1434

targeting insulin-like growth factor 1 receptor currently in a Phase 1 trial; and FPI-2068, a bispecific IgG-based EGFR cMET targeted radioconjugate currently in a Phase 1 trial. Fusion has multiple other pipeline programs that will soon be entering into early FIH trials. In addition, Fusion is pursuing combination programs between RCs and other therapeutic modalities including DNA Damage Response Inhibitors (DDRis) and immune-oncology agents. To support execution for these programs, Fusion has a fully operational Good Manufacturing Practice (GMP) compliant state-of-the-art radioconjugate manufacturing facility to meet supply demand for our growing pipeline of RCs. Candidates for the Scientist, Theranostics role need to work on a hybrid basis out of our Boston, Massachusetts office. Responsibilities Assist in the development of, and adherence to, imaging trial documents (e.g., Image Review Charter, Imaging Manual, Data Transmittal Forms, and Dosimetry Manuals). Provide subject matter expertise to internal and external stakeholders in matters of image acquisition, storage, review, and processing. Maintain an archive of imaging related data for ongoing and completed trials. Collaborate with clinical operations in the oversight, conduct and management of imaging-related aspects of clinical studies in accordance with the clinical protocol, study manuals and plans, and timelines while ensuring quality in accordance with GCP and ICH guidelines. Assist with the management of in-house processing of image data and internal dosimetry efforts to support ongoing research and multi-disciplinary department and company initiatives. Provide support for clinical data review; assist in generation of clinical research reports and presentations including abstracts, posters, and publications. Provide support to clinical site staff and investigators pertaining to preparation, administration, and waste management of imaging and therapeutic radiopharmaceuticals. Respond to radiation safety questions and concerns regarding the use of diagnostic and therapeutic radiopharmaceuticals and precautions. Have a working knowledge and understanding of modern electronic infrastructures relevant to radiological imaging such as

DICOM, PACS, IHE

models, image processing and advanced visualization. Willingness to travel when needed (5-10%) Qualifications The candidate should have a Bachelor of Science degree with a life science focus from an accredited educational institution and

NMTCB/ARRT

(N) certification in nuclear medicine or equivalent. Additional training in radiation safety (NMTCB(RS)) and/or medical physics with an advanced master's qualifications is preferred but not required. Minimum of at least 5 years of clinical experience. Experience working in clinical trials for 2-5 years is preferred but not required. Demonstrated technical and analytical problem-solving skills. Scientific expertise in SPECT and PET imaging is recommended, including acquisition, reconstruction and uploading of images. Training in Good Clinical Practices (GCP), Quality Assurance/Compliance (QA/QC) in a clinical trial setting is preferred. Experience with radioactive materials license amendment process with the NRC and Agreement States. Familiar with Radiation Safety Officer (RSO) responsibilities. Ability to clearly articulate and present the role and impact of molecular imaging on decision making within drug discovery and development. Self-motivation and exceptional verbal and written communication skills. Ability to multi-task and work effectively in a team or independently on assigned tasks. Proficiency in business computer skills and experience with medical imaging workstations (i.e., MIM), dosimetry software, and/or PACS preferred. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, or status as a protected veteran. The annual base pay for this position ranges from $92,908.00 to $139,362.00. Our positions offer eligibility for various incentives—an opportunity to receive short-term incentive bonuses, equity-based awards for salaried roles and commissions for sales roles. Benefits offered include qualified retirement programs, paid time off (i.e., vacation, holiday, and leaves), as well as health, dental, and vision coverage in accordance with the terms of the applicable plans. Date Posted 12-May-2026 Closing Date 30-May-2026 Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form. AstraZeneca is a global, science-led, patient-focused biopharmaceutical company. We focus on discovering, developing and commercialising prescription medicines for some of the world's most serious diseases. But we are more than one of the world's leading pharmaceutical companies. At AstraZeneca, we're dedicated to being a Great Place to Work. Where you are empowered to push the boundaries of science, challenge convention and unleash your entrepreneurial spirit. To embrace differences and take bold actions to drive the change needed to meet global healthcare and sustainability challenges. There is no better place to make a difference in medicine, patients, and society. An inclusive culture where you will connect different thinking to generate new and valuable opportunities. Where you will find a commitment to lifelong learning, growth and development for all. Our Inclusion & Diversity (I&D) mission is to create an inclusive and equitable environment where people belong, using the power of our diversity to push the boundaries of science to deliver life-changing medicines to patients. Inclusion and diversity are fundamental to the success of our company, because innovation requires breakthrough ideas that only come from a diverse workforce empowered to challenge conventional thinking. We're curious about science and the advancement of knowledge. We find creative ways to approach new challenges. We're driven to make the right choices and be accountable for our actions. As an organisation centred around what makes us human, we put a big focus on people. Across our business, we want colleagues to wake up excited about their day at the office, in the field, or in the lab. Along with our purpose to bring life-changing medicines to people across the globe, we have a promise to you: to help you realise the full breadth of your potential. Here, you'll do work that has the potential to change your life and improve countless others. And, together with your team, you'll shape a culture that unites and inspires us every day. This is your life at AstraZeneca.