Postdoctoral Research Associate Kirchner Lab

Job TitlePostdoctoral Research Associate - Kirchner Lab Agency Texas A&M University Health Science Center Department Medical Physiology Proposed Minimum SalaryCommensurate Job LocationBryan, Texas Job TypeStaff Job Description Our Commitment Texas A&M University is committed to enriching the learning and working environment by promoting a culture that respects all perspectives, talents & lived experiences. Embracing varying opinions and perspectives strengthens our core values which are: Respect, Excellence, Leadership, Loyalty, Integrity, and Selfless Service. Who we are As one of the fastest-growing academic health centers in the nation, Texas A&M Health encompasses five colleges and numerous centers and institutes working together to improve health through transformative education, innovative research and team-based health care delivery. What we want The Postdoctoral Research Associate is responsible for conducting research into their field of expertise. This position is in the Kirchner Laboratory within the Department of Medical Physiology at Texas A&M College of Medicine. The Postdoctoral Research Associate will utilize the skills and expertise granted to them by their education and experience to complete research projects in their field of expertise. This position will perform patch clamp electrophysiology, calcium imaging, and immunohistochemistry for to study the neurophysiology of vasopressin and oxytocin neurosecretory neurons, their role in hydromineral balance, and their dysfunction in a rat model of heart failure. Writes and may contribute to research papers, articles, and publications. Assists with the preparation and cleaning of worksite. May collaborate with other researchers and/or faculty both within and outside of Texas A&M. What you need to know

Salary:

Will be commensurate based on the selected hire's education and experience.

Location/Schedule:

Bryan, TX/ Full-Time; This position may require work beyond normal office hours and/or work on weekends Please note: This position is grant funded; future employment may be contingent upon future funding. Apply! Submitting a cover letter, CV/Resume to assist us with the review process. You may upload these documents on the application under CV/Resume. Required Education and Experience Appropriate PhD in neuroscience, neurophysiology, or a related field.

Preferred Qualifications Patch Clamp electrophysiology:

Prepping solutions for recordings, cutting live brain slices on a vibratome, and performing voltage and current clamp recordings in neurons. Using optogenetics, photolytic uncaging, chemogenetics, fluorescent biosensors, electrical stimulation, and application of pharmacologic compounds during patch clamp experiments. Maintaining the electrophysiology rig, keeping accurate records of experiments, performing data analysis, and creating figures for publications and grants.

Rodent survival surgery:

Coronary ligation (heart failure surgery) for studying the disease in electrophysiology experiments. Stereotaxic delivery of AAVs encoding fluorescent tracers, DREADDs or opsins to be used in electrophysiology experiments.

Calcium imaging:

Utilizing calcium dyes or genetically encoded calcium sensors (i.e. GCaMP) to measure and quantify intracellular calcium levels in a live brain slice preparation. Performing these experiments simultaneously with patch clamp. Immunohistochemistry (IHC) Transcardial perfusion, fixation, cryostat sectioning, staining, and mounting tissue specimens. Visualization and analysis of IHC imaging data Multiunit electrophysiological experiments, particularly using

Neuropixels Software Expertise and Data Analysis:

pCLAMP, ImageJ, MatLab, Imaris Additional expertise using Igor Pro, Prism, Python, and Adobe Illustrator is a plus. Experience training other laboratory members in the techniques listed above. Responsibilities Research Under general supervision, is responsible for conducting research into their field of expertise. Utilizes knowledge and skills granted to them by their education and expertise to complete research projects in their field of expertise. Assists with the preparation and cleaning of worksite. Analyzes research data and summarizes results. Writes and may contribute to research papers, articles, and publications. Mentoring May assist, mentor, and/or supervise student researchers and/or graduate students who are working on research related to the project. Presentations Prepares presentation materials on research topic that may be presented to small and/or large groups. Actively participates in the preparation of required technical progress reports to research sponsors. Professional Development Apply for career-appropriate grants and fellowships under the guidance of the PI. Travels to scientific conferences to give presentations. Why Texas A&M University? We are a prestigious university with strong traditions, Core Values, and a community of caring and collaboration. Amenities associated with a major university, such as sporting and cultural events, state-of-the-art recreation facilities, the Bush Library and Museum, and much more await you. Experience all that a big city has to offer but with a reasonable cost-of-living and no long commutes. Medical, prescription drug, dental, vision, life and AD&D, flexible spending accounts, and long-term disability insurance with Texas A&M contributing to employee health and basic life premiums 12-15 days of annual paid holidays Up to eight hours of paid sick leave and at least eight hours of paid vacation each month Automatic enrollment in the

Teacher Retirement System of Texas Health and Wellness:

Free exercise programs and release time

Professional Development:

All employees have access to free LinkedIn Learning training, webinars, and limited financial support to attend conferences, workshops, and more Educational release time and tuition assistance for completing a degree while a Texas A&M employee Living Well, a program at Texas A&M that has been built by employees, for employees Instructions to

Applicants:

Applications received by Texas A&M University must either have all job application data entered, or a resume attached. Failure to provide all job application data or a complete resume could result in an invalid submission and a rejected application. We encourage all applicants to upload a resume or use a LinkedIn profile to prepopulate the online application. All positions are security-sensitive. Applicants are subject to a criminal history investigation, and employment is contingent upon the institution's verification of credentials and/or other information required by the institution's procedures, including the completion of the criminal history check. Equal Opportunity/Veterans/Disability Employer. Howdy and thank you for your interest in a career with Texas A&M University. As the flagship campus of The Texas A&M University System, we are located in College Station, Texas with a student population of more than 74,000 and nearly 14,000 faculty and staff. The Spirit of Aggieland is unmistakable. We are a unique American institution, fostering a culture of friendliness, compassion and respect for one another. Our unique history and rich traditions make Texas A&M special. From our benefits package and professional development opportunities to our retirement programs, Texas A&M is a great place to work. Your path to a great career starts here! Equal Opportunity/Veterans/Disability Employer. If you need assistance in applying for this job, please contact (979) 845-5154.

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