Bioinformatics Scientist/Manager
Actalent
Bothell, WA (In Person)
$197,600 Salary, Full-Time
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Job Description
- PMS or equivalent in computational biology, bioinformatics, biostatistics, computer science, genomics or a related field with postdoctoral research experience in Cancer Biology; or MS in cancer biology or related field with established advanced capability and track record in developing and applying computational and bioinformatics methods.
- Five years or more of post-PhD academic and/or industry experience working with large, multidimensional, genomics datasets (e.g. NGS, RNA-Seq, transcriptomics, proteomics, flow cytometry, etc.)
- Strong foundation in molecular biology and next-generation sequencing technologies (DNA-seq, RNA-seq, targeted panels, WES/WGS) Technical Qualifications NGS Data Analysis
- Hands-on experience analyzing NGS data end-to-end, including: o Raw data processing and quality control (FASTQ, BAM/CRAM) o Alignment, variant calling, and/or expression quantification o Annotation and interpretation of variants or molecular signatures
- Familiarity with common NGS tools and frameworks (e.g., BWA, Bowtie2, GATK, SAMtools, Picard, STAR, Salmon, Kallisto) Pipeline Development & Automation
- Proven experience developing, optimizing, and maintaining reproducible bioinformatics pipelines
- Familiarity with workflow management systems (e.g., Nextflow, Snakemake, WDL/Cromwell)
- Strong scripting and automation skills in Bash, Python, and R. Software & Data Engineering
- Experience writing code versioned with Git/GitHub
- Ability to design modular, scalable, and maintainable analytical workflows
- Familiarity with containerization technologies (Docker, Singularity/Apptainer) Statistical & Computational Skills
- Solid understanding of statistics and applied methods relevant to genomics (e.g., differential expression, QC metrics, batch effects)
- Experience with data visualization and reporting for scientific and non-scientific audiences
- Ability to assess analytical performance, accuracy, and robustness Computing Environments
- Experience working in Linux/Unix environments
- Familiarity with high performance computing (HPC) clusters and/or cloud platforms (AWS, GCP, Azure)
- Understanding of data storage, data transfer, and compute optimization in large-scale datasets Industry & Regulated Environment Experience
- Experience supporting product development, diagnostics, or translational research in an industry setting
- Familiarity with assay validation concepts, analytical performance metrics, and documentation requirements
- Exposure to regulated or quality-driven environments (e.g., CLIA, CAP) is a strong plus Collaboration & Communication
- Ability to clearly communicate technical results, assumptions, and limitations to cross functional teams
- Experience collaborating with wet lab scientists, software engineers, and program partners
- Strong documentation skills for pipelines, analyses, and standard operating procedures (SOPs) Job Type & Location This is a Contract position based out of Bothell, WA.
- Medical, dental & vision
- Critical Illness, Accident, and Hospital
- 401(k) Retirement Plan - Pre-tax and Roth post-tax contributions available
- Life Insurance (Voluntary Life & AD&D for the employee and dependents)
- Short and long-term disability
- Health Spending Account (HSA)
- Transportation benefits
- Employee Assistance Program
- Time Off/Leave (PTO, Vacation or Sick Leave) Workplace Type This is a fully onsite position in Bothell,WA.
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