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Scientific Software Developer II - Modeler

Job

Cadence Design Systems

Santa Fe, NM (In Person)

Full-Time

Posted 03/05/2026 (Updated 4 days ago) • Actively hiring

Expires 6/21/2026

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Job Description

Scientific Software Developer II - Modeler Cadence Design Systems 4.4 ( ) Multiple Locations on company site for later Why you should apply for a job to
Cadence Design Systems :
Ranked as one of the 4.4/5 in overall job satisfaction 4.4/5 in supportive management 87% say women are treated fairly and equally to men 89% would recommend this company to other women 87% say the CEO supports gender diversity Ratings are based on anonymous reviews by Fairygodboss members. See all reviews Parental leave is available for both paternity and maternity Flexible work options available 88% of employees at Cadence say it is a great place to work compared to 57% of employees at a typical U.S.-based company. # R53423 Position summary heminformatician to join our team of experts in mathematics, computational modeling, and medicinal chemistry. This highly focused team will work together to drive forward technology which leverages OpenEye's Orion platform to better enable scientists in the pharmaceutical industry working on projects from lead development to clinical candidate selection. This role will require interactions with customers and OpenEye's scientific and technical teams. What you'll do: Extend OpenEye's programming toolkits by developing and implementing new and useful scientific and technical features to aid customers in developing bespoke solutions. Explore methods for further enhancing OpenEye's virtual screening platform (including OMEGA, ROCS, FastROCS, OEDocking). chemistry/cheminformatics expertise with ML experts to build robust, scalable models to support data-driven decision making. Work on retrospective and prospective projects both internally and with collaborators to validate methodologies. Work with Orion project team to further optimize compound design workflows in Orion.
What you should have:
PhD (or equivalent experience) in computational chemistry, chemistry, cheminformatics, or related field with 0 - 3 years relevant experience Knowledge of some traditional computational chemistry approaches such as docking, virtual screening, molecular modeling, etc. Programming expertise, ideally in c++ and/or python preferably with experience using AI coding agents Experience in or desire to learn about the pharmaceutical industry Strong desire to find practical solutions to challenging problems Demonstrated ability to work both as part of a team and independently The following are a PLUS, but not required: Experience with OpenEye software/toolkits Expertise with diffusion models, transformers or 3D ML representations Experience with synthetically accessible, pharmaceutically relevant generative chemistry
Benefits:
We are passionate about the welfare of our employees and offer competitive benefits that include medical, dental, vision, flexible working schedule, 401k retirement plans, paid vacation, paid sick leave, home internet costs, public transportation reimbursement, and much more. Please submit your cover letter and resume as one document. OpenEye Scientific Software is an Equal Opportunity Employer. We're doing work that matters. Help us solve what others can't. Why you should apply for a job to
Cadence Design Systems :
Ranked as one of the 4.4/5 in overall job satisfaction 4.4/5 in supportive management 87% say women are treated fairly and equally to men 89% would recommend this company to other women 87% say the CEO supports gender diversity Ratings are based on anonymous reviews by Fairygodboss members. See all reviews Parental leave is available for both paternity and maternity Flexible work options available 88% of employees at Cadence say it is a great place to work compared to 57% of employees at a typical U.S.-based company.