Statistical Science Director - Early Oncology

Are you ready to shape statistical strategy that advances transformative medicines for people living with cancer? Do you see yourself steering high-impact decisions from early discovery through regulatory approval and beyond, so patients benefit sooner? Main duties and responsibilities In this role you will be responsible in leading the strategic, statistical thinking and contributions to the Development Plans, Regulatory Strategy, Health Technology Assessment and Commercial Presentation for indications/projects within an AZ product team. You will provide leadership to statistical staff on the indications/projects so that all work is carried out with regards to AZ standards and external regulations; through partnership with experts, developing design options and providing high quality decision support to enable the business to make informed decisions; quantifying the benefit, risk, value and uncertainty of the emerging product profile. You will be holding CRO/Partners accountable for the high quality standards of their deliverables. You will represent AZ and Statistics to Health Authorities and Reimbursement/Payer Organisations for specific projects/indications. You will apply expert skills to investigate, apply novel statistical approaches, for relevant statistical issues and/or regulatory guidance and/or value demonstration. You will mentor/coach and support the education and training of Statistics staff in the technical arena. Requirements Essential MSc or PhD degree in Statistics, Biostatistics, or related quantitative fields, or equivalent course work/ technical experience Understanding of regulations/developments in the area of Clinical Development and Biostatistics 5 years experience as a statistician with clinical trials, pharmaceutical development, regulated research, and/or related areas of statistical applications A collaborative mindset A general dedication to and ability to apply expertise to problem solving Experience with relevant statistical software Ability to apply statistical techniques in the analysis of data from clinical studies

Desirable Skills/Experience:

TA or disease area knowledge expertise Exposure to business development opportunities (e.g.in licencing) Project management skills Proficiency in programming SAS and/or R and Python When we put unexpected teams in the same room, we unleash bold thinking with the power to encourage life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our outstanding and ambitious world. The annual base pay (or hourly rate of compensation) for this position ranges from $ 188,279.20 - 282,418.80 USD . Our positions offer eligibility for various incentives—an opportunity to receive short-term incentive bonuses, equity-based awards for salaried roles and commissions for sales roles. Benefits offered include qualified retirement programs, paid time off (i.e., vacation, holiday, and leaves), as well as health, dental, and vision coverage in accordance with the terms of the applicable plans. Why AstraZeneca Here, your statistical leadership fuels a pipeline that pushes scientific frontiers and brings new options to people with the toughest cancers. You will collaborate across disciplines and with leading academic and clinical partners, applying advanced methods to complex development questions at global scale. We back bold ideas with the data, technology and investment needed to deliver, and we value kindness alongside ambition—so you can take smart risks, grow your craft and see your work turn into medicines that make a measurable difference. Step into this role to build pivotal evidence and accelerate the next generation of cancer medicines—your impact starts here! Date Posted 11-Mar-2026 Closing Date 10-Mar-2026 Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.