Principal Analyst, Manufacturing IT Systems

Overview Waters is looking for an experienced Principal Manufacturing IT Systems Analyst to define, govern and advance Manufacturing Execution Systems (MES), Laboratory Information Management Systems (LIMS) and Computerized Maintenance Management Systems (CMMS) in support of Waters global manufacturing footprint. This role sits at the intersection of manufacturing operations, digital manufacturing strategy, and enterprise integration, ensuring shop‑floor and asset management systems enable scalable growth, regulatory compliance, operational excellence, and rapid integration of new capabilities including acquisitions and external manufacturing partners. The position operates with broad autonomy, shapes long‑term manufacturing systems strategy, and influences decision‑making at site, regional, and global levels. Responsibilities Define and maintain global standards, architectures, and governance models for manufacturing execution and asset management systems. Shape the long‑term MES and CMMS roadmap, aligned with Digital Manufacturing, Global Operations strategy, and enterprise architecture. Evaluate emerging technologies and vendors to inform build vs buy and platform rationalization decisions. Enable Digital Manufacturing capabilities across Global Operations, including Electronic Batch / Device History Records (eBMR/eDHR), Digital work instructions and operator execution, asset reliability, preventive and predictive maintenance. Serve as a trusted IT partner to Global Operations leadership, site operations, engineering, quality, and maintenance teams. Balance global standardization with site level operational needs, enabling controlled flexibility where required. Influence operating models, processes, and data standards through system design rather than point solutions. Develop integration playbooks for onboarding new sites, partners, or technologies into the Global Operations landscape. Collaborate closely with Automation, IT/OT, Infrastructure, and Cybersecurity teams to ensure secure, resilient manufacturing architectures. Ensure MES and CMMS solutions meet GxP, data integrity, and regulatory requirements (e.g., 21 CFR Part 11). Provide oversight and direction for major MES and CMMS programs, including vendor led implementations. Qualifications Bachelor's degree in Information Systems, Engineering, Computer Science, or equivalent experience. Extensive experience in manufacturing IT systems within complex or regulated environments. Deep expertise in MES, CMMS and EAM platforms (e.g., Opcenter, Apriso, Tulip, Maximo, ServiceNow or similar). Strong understanding of manufacturing operations, maintenance processes, and shop floor execution. Proven experience operating at a global, multi site level. Strong knowledge of IT/OT convergence and manufacturing network design. Ability to operate effectively at both strategic and detailed technical levels. Company Description Waters Corporation (

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WAT) is a global leader in life sciences and diagnostics, dedicated to accelerating the benefits of pioneering science through analytical technologies, informatics, and service. With a focus on regulated, high-volume testing environments, our innovative portfolio harnesses deep scientific expertise across chemistry, physics, and biology. We collaborate with customers around the world to advance the release of effective, high-quality medicines, ensure the safety of food and water, and drive better patient outcomes by detecting diseases earlier, managing routine infections, and combating antibiotic resistance. Through a shared culture of relentless innovation, our passionate team of ~16,000 colleagues turn scientific challenges into breakthroughs that improve lives worldwide. Diversity and inclusion are fundamental to our core values at Waters Corporation. It benefits our employees, our products, our customers and our community. Waters complies with all applicable federal, state, and local laws. Qualified applicants are considered without regard to sex, race, color, ancestry, national origin, citizenship status, religion, age, marital status (including civil unions), military service, veteran status, pregnancy (including childbirth and related medical conditions), genetic information, sexual orientation, gender identity, legally recognized disability, domestic violence victim status, or any other characteristic protected by law. Waters is proud to be an equal opportunity workplace and is an affirmative action employer. All hiring decisions are based solely on qualifications, merit, and business needs at the time.