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Responsibilities:

•This position is for upcoming work and is contingent upon task award/funding. •This will be based out of Reston, VA Noblis is seeking a Principal Regulatory Scientist to support critical national security programs. In this role you will help ensure regulatory and product information is accurately represented in a secure database and web-based application. This system supports programmatic and regulatory decision-making for medical countermeasures intended to prevent, diagnose, or treat the effects of chemical, biological, radiological, nuclear, emerging infectious disease, and other operational threats. The Principal Regulatory Scientist will work closely with client program managers, product developers, scientists, regulatory professionals, data specialists, software engineers, and web application developers to translate FDA regulatory requirements, development milestones, evidence standards, and program risks into decision rules, data requirements, and logic for a web-based decision support engine. You will also collaborate with software developers, data architects, and end users to validate recommendations, test decision pathways, and ensure outputs are scientifically accurate, traceable, and appropriate for medical countermeasure development.

Responsibilities include:

Review, organize, and track regulatory documentation associated with medical countermeasure development programs, while maintaining awareness of evolving FDA requirements and communicating changes that may affect client programs or information-management needs. Compile and analyze quality performance data to identify trends and develop tools and systems for tracking performance measures, and interfacing with customers, and various stakeholders to resolve quality problems and provide technical guidance, participating in or leading quality improvement initiatives and program implementations. Distill complex scientific and regulatory information into concise findings that can be used by technical experts, program managers, senior leaders, and software-development personnel. Evaluate data and documentation for accuracy, completeness, consistency, currency, provenance, traceability, and appropriate classification. Support migration, normalization, reconciliation, and validation of information from legacy systems and other data sources. Review software prototypes and application releases to verify scientific accuracy, regulatory relevance, usability, and alignment with client requirements. Identify opportunities to automate manual processes while preserving scientific quality, data integrity, traceability, and appropriate human review.

Required Qualifications:

PhD., Pharm.

D., M.D., or other relevant doctoral degree in toxicology, chemistry, biochemistry, biomedical engineering, regulatory science, or a related scientific discipline and at least 4 years of relevant experience. A master's degree in a relevant field may be considered with at least 6 years directly applicable experience. Demonstrated experience applying FDA regulatory requirements, guidance, and development pathways to assess evidence gaps, regulatory risks, and recommended next steps for medical countermeasure programs. Ability to evaluate nonclinical, clinical, CMC, and regulatory information and translate complex findings into clear, defensible decision support for multidisciplinary program teams and government stakeholders. Strong technical writing, verbal communication, presentation, facilitation, analytical, and organizational skills. Must be a US Citizen with an active secret clearance, and ability to obtain a top secret clearance.

Desired Qualifications:

Direct experience developing or evaluating medical countermeasures for chemical, biological, radiological, nuclear, emerging infectious-disease, or operational threats. Experience supporting a Department of War/Department of Defense, Department of Health and Human Services, or other federal medical countermeasure organization. Experience with FDA's Animal Rule and development programs in which human efficacy studies are unethical or infeasible. Experience with pre-EUA or EUA submissions and emergency-preparedness activities. Experience participating in software user-acceptance testing, requirements traceability, data validation, or quality-assurance activities.

Overview:

Overview Noblis and our wholly owned subsidiaries, Noblis ESI and Noblis MSD, take on some of the nation's toughest challenges, delivering advanced solutions to our customers' most critical missions. We bring together leading scientific, engineering, and management expertise in a culture grounded in objectivity and collaboration, ensuring our work creates lasting impact across federal missions. We work with a broad range of government agencies in the defense, intelligence, and federal civilian sectors. Learn more and find opportunities at careers.noblis.org Why Work at Noblis At Noblis, we share a passion for excellence and innovation, and we create an environment where people can do meaningful work while maintaining the balance that keeps them energized and fulfilled. We seek out individuals with a natural curiosity and desire to collaborate and learn. We believe our people are our greatest strength, and we consistently seek exceptionally skilled, mission‑driven professionals who care deeply about doing work that enriches lives and makes our nation safer. Noblis has earned numerous workplace awards for our culture, our commitment to employee well‑being, and our dedication to meaningful, impactful work. We also maintain a drug‑free workplace. Remote/hybrid status is subject to change based on Noblis and/or government requirements. Commitment to

Non-Discrimination:

All qualified applicants will receive consideration for employment without regard to race, color, ethnicity, sex, age, national origin, religion, physical or mental disability, pregnancy/childbirth and related medical conditions, veteran or military status, or any other characteristics protected by applicable federal, state, or local law. If reasonable accommodation is needed to participate in the job application or interview process, to perform essential job functions, and/or to receive other benefits and privileges of employment, please contact us. EEO is the Law | E-Verify | Right to

Work Total Rewards:

At Noblis we recognize and reward your contributions, provide you with growth opportunities, and support your total well-being. Our offerings include health, life, disability, financial, and retirement benefits, as well as paid leave, professional development, tuition assistance, and work-life programs. Our award programs acknowledge employees for exceptional performance and superior demonstration of our service standards. Full-time and part-time employees working at least 20 hours a week on a regular basis are eligible to participate in our benefit programs. Other offerings may be provided for employees not within this category. We encourage you to learn more about our total benefits by visiting the Benefits page on our Careers site. Compensation at Noblis is determined by various factors, including but not limited to, the combination of education, certifications, knowledge, skills, competencies, and experience, internal and external equity, location, clearance level, as well as contract-specific affordability, organizational requirements and applicable employment laws. The projected compensation range for this position is based on full time status. For part time or on-call staff, compensation is proportionately adjusted based on hours worked. While monetary compensation is important, it's just one component of Noblis' total compensation package.

Posted Salary Range:

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Principal Regulatory Scientist

Medical Laboratory Scientist 2