Sr Dir, Gen Mgr & Strategic Ally Lead Intl

Senior Director, General Manager and Strategic Alliance Lead, International Partner Markets Who we are: At Agios, we are fueled by connections to transform rare diseases. We foster an inclusive, collaborative culture

• one that sparks bold thinking and strengthens our connections with each other and with the rare disease communities we serve. We embrace diverse backgrounds with respect, active listening, and a commitment to inclusion
• because our differences shape how we hire, collaborate, and innovate. Our team's proven track record of executional excellence, combined with our depth of expertise and dedication, enables us to develop innovative medicines that reflect the priorities of rare disease communities. Our commitment is more than scientific
• it's deeply personal, grounded in the meaningful connections we have built.

To learn more, visit www.agios.com and follow Agios on LinkedIn and X .

The impact you will make:

Agios Pharmaceuticals is searching for a dynamic Senior Director, General Manager and Strategic Alliance Lead, International Partner Markets to join the Global Commercial Strategy and Access Team. This is a very exciting time to join our team, as Pyrukynd has secured approval and was recently launched for thalassemia in the US, Saudi Arabia and the United Arab Emirates. Launch preparation is also underway in Europe and there is potential to expand in all regions to Sickle Cell Disease with regulatory filing preparations underway on the back of meaningful Phase III data. While Agios has a commercial team in the US, Agios has chosen to partner with two strong companies in the GCC (Gulf Corporation Council) and Europe, Newbridge Pharmaceuticals and Avanzanite Biosciences, who are leading distribution and commercialization of Pyrukynd in each respective region. The General Manager and Strategic Alliance Lead, International Partner Markets, will be accountable for the commercial performance, overall business execution, operating model, P&L, and overall alliance with these two partners. This role represents an opportunity for an individual with deep international commercial experience to lead Agios' first expansion outside of the US in rare disease

• shaping how Agios can maximize reaching patients outside the US.

This individual reports to the VP, Global Strategy and International Commercialization.

What you will do:

Own the overall performance

• P&L•in partner markets including the GCC and Europe.

There is potential opportunity for expansion into additional markets in the future. Serve as the strategic alliance lead for each partnership, organizing every Joint Steering Committee, Quarterly Business Review, and ongoing functional collaboration. Drive a transparent, collaborative, and connected culture with our partners. Meet with partners near daily as the face of Agios. Cultivate and build strong cross functional relationships within Agios, including with the Global Commercial Lead, Market Access, Medical, HEOR, Supply Chain and other key functions across the Pyrukynd business to incorporate broader global strategy into local execution with partners. Define Agios' brand presence and performance outside the US in partner markets. Contribute to the overall ex-US expansion strategy for Agios, as applicable, partnering across a wide breadth of functions. Give a perspective of how much influence, autonomy and direction a person in this role will have in a variety of areas Include management of internal staff or external resources What you bring: Bachelor's degree in business or science related field; MBA or PhD a plus At least 15 years' experience in pharma / biotech Deep International commercial experience

• particularly in the GCC and Europe
• including sales, marketing, and commercial strategy.

Successfully drive regulatory, access and commercial timelines and objectives. Experience leading with an alliance partner; prior experience managing a distribution partner a plus Strong commercial understanding of rare diseases, including rare blood indications Excellent communication and presentation skills. They will be able to gain credibility, engender trust and influence all levels

• both within Agios as well as across our partner companies.

Operate with a sense of urgency. Accountability to make timely decisions with well-balanced analysis and intuition, drive executional excellence, strong project management skills Ability to thrive in a cross-functional, highly collaborative, and fast-paced environment. Naturally connects and builds strong relationships with peers Agility to search and respond to drivers of changes, challenge the status quo, mobilize resources, and learn with an open mind

Travel Requirements:

This role will require travel

• generally between 1-2 weeks per month.

Travel will be required to meet with partners in the GCC and Europe, attend conferences, and occasionally visit Agios headquarters in Boston, USA for major internal Concerned that you don't check off every box in the requirements listed above? Please apply anyway! At Agios, we value each other's differences and recognize that teams thrive when everyone brings their unique experiences to the table. We are dedicated to building an inclusive, diverse, equitable, and accessible environment where all employees can bring their whole selves to work. If you're excited about this role but your previous experience doesn't align perfectly with the job description, we still encourage you to apply. You may be just the right candidate for this role or another opening!

Work Location:

Switzerland/Remote:

Work location for this role is remote within Switzerland. Remote employees work entirely from home except for attending Company sponsored events and meetings, and for work related travel as described above.

What we will give you:

Deliberate Development. Your professional growth as one of our top priorities. Flexibility . We're all about individual needs. We embrace different perspectives, work styles, health and wellness approaches, care of families and productivity. When you're at your best, we're at our best. Premium benefits package. We invest in the health, wellbeing, and security of our people with a premium benefits package that is well-rounded and flexible to help meet the varied personal and professional needs of every member of our team. Competitive and equitable performance-based compensation. This includes base salary and both short

• and long-term incentives that are connected to our business strategy and vary based on individual and company performance.

Psychological safety. We support an environment of fearlessness. We want you to share your ideas, speak candidly and take data-informed risks to help push the boundaries. Commitment to diversity. We strive to foster a welcoming workplace where everyone can thrive. We're continuously looking to improve the inclusivity of our workforce. Commitment to community. We're an active participant in the communities that surround us

• the communities where we live, and the community of people and their loved ones in need of better treatment options for conditions that are often overlooked.

Interested in learning more about what makes our culture unique? Visit the Inside Agios section of our website.