$246,000.

00 life insurance, paid time off United States, Iowa, Des Moines Aug 22, 2026

Department:

106800

Technical Operations Location:

San Diego, USA

Remote Be a part of a global team that is inspired to make a difference in the lives of people living with rare disease.

At Travere Therapeutics, we recognize that our exceptional employees are vital to our success. We are a dedicated team focused on meeting the unique needs of rare patients.

Our work is rewarding

both professionally and personally
because we are making a difference. We are passionate about what we do. We are seeking talented individuals who will thrive in our collaborative, diverse, fast-paced environment and share in our mission
to identify, develop and deliver life-changing therapies to people living with rare disease.

We stick by our values centered on patients, courage, community, and collaboration to pursue our vision of becoming a leading biopharmaceutical company dedicated to the delivery of innovation and hope to patients in the global rare disease community. At Travere Therapeutics, we are in rare for life. We continue to courageously forge new paths as we move toward a common goal of elevating science and service for rare patients.

Position Summary:

The Director, Technical Operations (Small Molecule CMC) will provide technical oversight for small molecule API development and manufacturing activities conducted at Travere CDMOs. Serving as a key technical point of contact, this role is a critical contributor within Technical Operations (CMC) and broadly supports the product development, clinical manufacturing, commercial launch planning, logistics, and lifecycle management of small molecule drug products. This individual will collaborate closely with Quality, Regulatory Affairs, Clinical, and Supply Chain to ensure alignment, risk management, and successful achievement of program milestones. The successful candidate will bring substantial experience in small molecule API development and manufacturing, including ability to help drive CMC strategy for a late-stage development asset.

Responsibilities:

Provide technical oversight of API production, scale up, process characterization, and process performance qualification (PPQ) for a small molecule, solid oral drug product manufactured at Travere CDMOs.\nReview and approve manufacturing-related documentation, including change notifications, batch records, process development, tech transfer, process characterization, and validation protocols/reports.\nVerify suitability, qualification, and validation status of processes at CDMOs and other external laboratories.\nProvide technical support for GMP quality management systems, including deviations, investigations, CAPAs, change controls, regulatory submissions, and facility inspections.\nCollaborate with internal and external project teams to support CMC development, clinical supply, commercialization, and lifecycle management of small molecule drug products.\nAuthor and review technical documents and regulatory submission content, including INDs, IMPDs, and NDAs.\nMaintain up-to-date knowledge of US and EU GMP requirements, ICH guidelines, and other regulatory expectations applicable to pharmaceutical development and manufacturing.\nReview project scope, timelines, and deliverables to ensure CDMO activities meet contractual obligations, quality standards, and program objectives.

Education/Experience Requirements:

Bachelor's degree in Life Sciences, Chemistry, Pharmaceutical Sciences, Biochemistry, Chemical Engineering, or a related discipline required. Equivalent combination of education and applicable job experience may be considered\nM.S., Ph.D., or other advanced degree in a related discipline preferred\n10+ years of relevant experience (depending on degree) in small molecule API development and manufacturing with emphasis on late-phase clinical development, scale-up, and commercialization\nExpert knowledge and extensive CMC experience advancing small molecule APIs from process development through process characterization, PPQ, commercialization, and tech transfers in support of solid oral dosage form programs\nExtensive experience managing global CDMOs, third-party manufacturers, and testing labs.\nBroad knowledge and experience with phase-appropriate cGMP requirements and applicable US, EU, and ICH guidelines\nDemonstrated ability to prepare and review CMC sections of regulatory filings, including

INDs, IMPDs, and NDAs Additional Skills/Experience:

The ideal candidate will embody Travere's core values: Courage, Community Spirit, Patient Focus and Teamwork\nDriven, intelligent, passionate about making a difference for patients with rare diseases\nStrong professional experience in a similar role within the pharmaceutical industry, preferably in small molecule development and manufacturing for solid oral dosage forms\nSuccessful record of creating and managing complex project plans, timelines, budgets, and development of risk mitigation strategies\nAbility to adapt to modification and changes to project plans, demonstrating flexibility to implement new strategies and tactics to accommodate these changes\nTeam player and strong interpersonal and organizational skills and excellent verbal and written communication skills\nExcellent decision-making and collaboration skills with strong attention to detail\nSix Sigma and statistical knowledge is a plus\nAbility to travel 10-20% domestically and internationally\nAll positions have an essential job function to be able to perform face to face work with colleagues and/or onsite in San Diego\nNo role is expected to be 100% remote

Total Rewards Offerings:

\nTravere provides comprehensive total rewards offerings that demonstrate our commitment as a diverse, equitable, people-centric, and pay-for-performance organization.

Benefits:

Our benefits include premium health, financial, work-life and well-being offerings for eligible employees and dependents, wellness and employee support programs, life insurance, disability, retirement plans with employer match and generous paid time off.

Compensation:

Our competitive compensation package includes a combination of both cash compensation (base pay and short-term incentive) and long-term incentive compensation (company stock), designed to recognize, retain, and reward employees.

Target Base Pay Range:

$189,000.00

$246,000.00
This information is current as of the date of this posting and may be modified in the future.

Actual pay offered to a candidate will depend on a variety of factors including the candidate's experience, education, skills, and location. Travere will accept applications on an ongoing basis until a candidate is selected for the position. Travere Therapeutics, Inc. is an EEO/AA/Veteran/Disability Employer. If you require a reasonable accommodation to complete the application or interview process, please contact us by sending an email to accommodations@travere.com. Please note that this email address is to be used exclusively to request an accommodation with the online application, interview or hiring process only. 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