Clinical Digital & AI Acceleration Innovation Manager

• Job Title:

• Clinical Digital Acceleration Innovation Manager

• Location:

• Cambridge, MA
• About the Job
• Join the engine of Sanofi's mission — where deep immunoscience meets bold, AI-powered research.

In R D, you'll drive breakthroughs that could turn the impossible into possible for millions. Sanofi is a leading bio-pharmaceutical company committed to advancing healthcare through groundbreaking research and development. Our dedicated function - Clinical Sciences & Operations (CSO) - plays a vital role in ensuring accurate and compliant clinical trial submissions and project operations, contributing to the approval of innovative therapies that transform patients' lives. Within CSO, the

• Modernization & Performance Office (MPO)
• acts as a key enabler of transformation and modernization, driving strategic initiatives that enhance efficiency, digital innovation, and operational excellence across the function.

As we continue our business transformation and drive excellence and innovation in our processes, we are seeking an exceptional professional to join us as Digital Acceleration & Innovation Lead. The Clinical Digital & AI Acceleration innovation Manager is a

• _CSO-wide, function-level leadership role_
• reporting to the Head of Clinical Digital & AI Acceleration, with
• _explicit accountability for shaping, steering, and realizing the value of CSO's digital and AI transformation agenda_
• across Sanofi's Clinical Sciences & Operations (CSO). The role
• _operates as a strategic authority rather than a delivery contributor_
• , responsible for
• _orchestrating global-scale digital and AI transformation_
• across clinical development,
• _with decision rights on portfolio prioritization, investment trade-offs, resource allocation, and execution strategies_
• within the transformation portfolio. The incumbent
• _directly influences CSO operating model evolution_
• , ensuring that digital and AI initiatives fundamentally reshape how clinical trials are designed, executed, and governed globally, with
• _measurable business, quality, and patient impact_
• . The position combines
• _strong digital and AI domains with function-level business and transformation leadership_
• , requiring the ability to
• _produce decision-grade insights for CSO leadership_
• , translate complex technology and regulatory constraints into
• _strategic value hypotheses_
• , and
• _steer outcomes across highly matrixed, regulated environments_
• . The role also
• _leverages competitive and technology intelligence to proactively shape CSO strategic choices_
• . If you are a visionary leader with a passion for transforming clinical operations processes and driving innovation in clinical research, we encourage you to apply for this exciting opportunity. Join our team and contribute to our mission of improving patient outcomes through cutting-edge therapies.
• About Sanofi
• We're an R D-driven, AI-powered biopharma company committed to improving people's lives and delivering compelling growth. Our deep understanding of the immune system - and innovative pipeline - enables us to invent medicines and vaccines that treat and protect millions of people around the world. Together, we chase the miracles of science to improve people's lives.
• Main Responsibilities
• Portfolio Management
• + •_Co-own and lead CSO Digital & AI transformation initiatives at function level_•, ensuring alignment with CSO strategy, business priorities, and value realization commitments.

+

• _Exercise decision authority_
• on initiatives prioritization, sequencing, and trade-offs to
• _maximize CSO-wide value and time-to-impact._
• + Align strategically and operationally
• _CSO's flagship transformation initiatives (e.g., ACT4Patients & eDEV)_
• to ensure
• _coherence, integration, and early realization of business outcomes_
• + •_Continuously challenge and recalibrate the transformation roadmap_•based on business performance data, field feedback, and competitive intelligence + Ensure •_global visibility and governance alignment_•across all internal and external digital innovation initiatives (Clinical Innovation, external forums, partnerships, etc.

) +

• _E_•_volve the Initiative Portfolio Management Office (iPMO) as a CSO governance and decision-enablement mechanism_•, not a procedural framework + Define, institutionalize, and •_enforce governance standards_•(business cases, ROI logic, value tracking, scale-up criteria, stop/pivot decisions) + •_Hold transformation teams accountable_•for outcome-based delivery and value realization, beyond milestone completion •Transformation Projects Leadership and Engagement management•+ •_Lead and sponsor_•selected •_high-impact, multi-million-euro, clinical-development critical transformation programs_•with Digital and/or AI components + •_Accountable for end-to-end outcomes,_•including strategic alignment, financial performance, adoption, scale-up, and sustained value delivery + •Direct and validate:•Competitive and technology intelligence to inform strategic positioning, function-level business needs and value hypotheses, prioritization of business-driven requirements shaping product and roadmap decisions & gaps analysis against existing solutions and operating models + •_Provide strategic direction_•on vendor models, sourcing strategies, and contractual frameworks in alignment with CSO transformation priorities + Oversee financial planning, investment phasing, and resource allocation to •_optimize enterprise ROI_•+ •_Influence CSO-wide positioning and integration_•of strategic platforms (e.

g., NEXUS, TrialPulse, Concierge) +

• _Ensure successful enterprise deployment and scale-up_
• , tracking realized benefits beyond pilot or proof-of-concept stages +
• _Own risk, dependency, and performance steering_
• , escalating and arbitrating at CSO leadership level as required
• Digital & AI Acceleration Capability Building
• + •_Define and own CSO-wide frameworks_•for measuring ROI, business impact, adoption, and maturity of digital, data, and AI initiatives + Provide •_portfolio-level, decision-grade visibility_•on solution interdependencies, capability impacts, and end-to-end process transformation + •_Institutionalize lessons learned_•and drive continuous improvement across the CSO transformation ecosystem + •_Continuously scan and interpret external technology, AI, and regulatory trends_•, translating them into actionable CSO transformation opportunities •Stakeholder Engagement & Collaboration•+ •_Engage, influence, and challenge CSO senior leadership and executive stakeholders_•as a trusted transformation and governance partner + •_Represent portfolio status, risks, and value realization in executive governance forums_•, providing clear recommendations and decision options + Co-lead •_CSO-level digital and AI strategy forums_•, shaping leadership understanding and adoption of innovation + Build and maintain •_enterprise partnerships beyond CSO_•(TMU, GRA, PV, Digital, etc.

) to accelerate transformation at scale +

• _Act as an enterprise integrator_
• between business, technology, and data teams, ensuring alignment and accountability
• About You
• Experience
• : +
• _Minimum 8 years_
• of experience in
• _enterprise digital transformation, portfolio leadership, or strategic program governance_
• + Proven track record
• _leading large-scale digital, data, or AI-enabled transformation_
• in complex, regulated environments + Strong experience in
• _BVA modeling, ROI tracking, and benefit realization_
• + Proven ability to
• _influence executive decisions and steer outcomes without direct hierarchical authority_
• + Understanding of clinical development, with
• _enterprise exposure to GCP, ICH-GCP, and operational quality frameworks_
• Leadership and Behavioral Competencies
• : +
• _Function-level strategic and systems thinker_
• , able to connect initiatives to value chains and operating-model shifts + Strong analytical rigor combined with
• _executive judgment and decisiveness_
• + •_Credible, confident presence at senior leadership and executive level_•+ Outcome- and value-oriented mindset with •_clear ownership and accountability_•+ Excellent cross-functional, cross-cultural leadership and orchestration skills •Education•: + Master's degree or PhD in a relevant field such as (but not limited to): Computer Science, Data Science/Analytics, Engineering (with focus on AI/ML).

MBA will be a plus.

• Languages
• + Fluent in English
• Why Choose Us?
• + Bring the miracles of science to life alongside a supportive, future-focused team.

+ Discover endless opportunities to grow your talent and drive your career, whetherit'sthrough a promotion or lateral move, at home or internationally. + Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact. + Takegood careof yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare,preventionand wellness programs and at least14 weeks' gender-neutral parental leave. Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law. ​\#GD-SA ​ \#LI-SA \#LI-Onsite​ \#vhd

• Pursue
• _progress_
• , discover
• _extraordinary_
• Better is out there.

Better medications, better outcomes, better science. But progress doesn't happen without people - people from different backgrounds, in different locations, doing different roles, all united by one thing: a desire to make miracles happen. So, let's be those people. At Sanofi, we provide equal opportunities to all regardless of race, colour, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, ability or gender identity. Watch our ALL IN video (https://www.youtube.com/watch?v=SkpDBZ-CJKw&t=67s) and check out our Diversity Equity and Inclusion actions at sanofi.com (https://www.sanofi.com/en/our-responsibility/equality-and-inclusiveness) ! _US and Puerto Rico Residents Only_ Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally inclusive and diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; natural or protective hairstyles; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law. _North America Applicants Only_ The salary range for this position is: $178,500.00 - $257,833.33 All compensation will be determined commensurate with demonstrated experience. Employees may be eligible to participate in Company employee benefit programs. Additional benefits information can be found through the LINK (https://benefits.sanofiusallwell.com/fleet/public/index/ba511bf8-5c32-4828-9861-ab985fffab90/?cid=sanofi) . Global Terms & Conditions and Data Privacy Statement (https://www.sanofi.com/en/careers/global-terms-and-conditions/) Sanofi is dedicated to supporting people through their health challenges. We are a global biopharmaceutical company focused on human health. We prevent illness with vaccines, provide innovative treatments to fight pain and ease suffering. We stand by the few who suffer from rare diseases and the millions with long-term chronic conditions. With more than 100,000 people in 100 countries, Sanofi is transforming scientific innovation into healthcare solutions around the globe. Discover more about us visiting www.sanofi.com or via our movie We are Sanofi (https://youtu.be/96EwNjb1TLo) As an organization, we change the practice of medicine; reinvent the way we work; and enable people to be their best versions in career and life. We are constantly moving and growing, making sure our people grow with us. Our working environment helps us build a dynamic and inclusive workplace operating on trust and respect and allows employees to live the life they want to live. All in for Diversity, Equity and Inclusion at Sanofi - YouTube (http://www.youtube.com/watch?v=SkpDBZ-CJKw&t=2s)