Principal Research Scientist I Eng

Principal Research Scientist I Eng Employer AbbVie Location North Chicago, IL Salary 124500 - 236500 USD Start date May 13, 2026 View more categories View less categories Discipline Regulatory , Science/R D , Biotechnology , Research Required Education Bachelors Degree Position Type Full time Hotbed BioMidwest , Best Places to Work Apply now Save job Click to add the job to your shortlist You need to sign in or create an account to save a job. Send job Job Details Company Job Details Company Description About AbbVie AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com . Follow @abbvie on LinkedIn, Facebook , Instagram , X and YouTube. Job Description R D Process Engineering, a part of AbbVies Development Sciences organization in Synthetic Molecules CMC (Chemistry, Manufacturing, and Controls), is responsible for designing and developing scalable processes to make drug substances and drug products, including small molecules and antibody drug conjugates (ADCs), throughout pre-clinical and clinical development stages. Responsibilities include synthetic route design, process definition, scale-up, and tech transfer for wide varieties of therapeutics and technologies to meet evolving pipeline demand. The R D Process Engineering team also partners with Biologics CMC Development and Aesthetics R D functions to provide active engineering support to enable robust process scale-up and manufacturing of biologics drug substances and drug products including toxins, lipid nanoparticles (LNPs), and cosmetic active ingredients (CAIs). We contribute to the development of innovative engineering technologies and create valuable intellectual property through the composition of matter, chemical processes, and technologies resulting in cost-effective commercial manufacturing processes. We support the development of the supply chain for pipeline molecules and help prepare and defend CMC regulatory content. Chemical Engineers within Process Engineering support pipeline projects through all phases of development. Early in development, engineers focus on establishing an enabling process that can be scaled-up successfully. In the later stages of development, engineers optimize the drug substance and drug product processes and lead manufacturing campaigns. Engineers also work cross-functionally to transfer the optimized process to manufacturing sites, develop control strategies, and prepare reports to support regulatory filings. Role Overview The successful engineering candidate will play a key role in the R D Process Engineering function.

The core deliverable of R D Process Engineering is to develop robust manufacturing processes and advance innovative technologies using strong engineering fundamentals. The ideal candidate will have significant prior reaction development and scale-up experience with demonstrated examples of scale up of small molecules and/or biologics from lab to pilot or production scales. The candidate is also expected to lead the identification and development of novel approaches and technologies to enhance process development efficiency and commercialization. The candidate must exhibit a collaborative nature in identifying process challenges on a wide range of projects, take part in a cross-functional team to deliver specific project needs, and take on a leadership role in developing and implementing solutions.

Key Responsibilities:

Develop robust manufacturing processes, supporting assets through all phases of development. Participate in and/or lead project teams towards development and characterization of new small and large molecule assets. Establish, communicate, and execute research plans. Develop commercial ready manufacturing processes in the laboratory and demonstrate the processes in the pilot plant. Set project strategies, define project responsibilities and timelines, and provide leadership in a matrixed team setting. Addresschallenging problems with chemical and biochemical reactions, separations, and/or isolations using demonstrated expertise in reaction kinetics, transport phenomena, and mathematical modeling. Develop and apply process analytical technologies and data-rich experimentation tools to build appropriate reaction and process understanding via model-guided experimentation. Build data driven and knowledge driven models to facilitate successful scale-up and tech transfer. Author and/or review technical documents summarizing process development efforts and contribute to regulatory filings. Exhibita collaborative nature in identifying process challenges on a wide range of projects and communicate findings and recommendations effectivelyby multi-disciplinary interactions with organic chemists, analytical chemists, process development engineers, pilot plant engineers, drug product development scientists, program managers, and regulatory affairs specialists. Author publications and present at scientific conferences. Qualifications BS, MS, or PhD in Chemical/Bio Engineering or a related field and 14+ (BS), 12+ (MS), or 6+ (PhD) years of relevant industrial experience. Job level will be commensurate with academic and/or industrial work experience. Ph.D. candidates with pertinent research exposure are also encouraged to apply. Candidates are expected to have a strong background in chemical engineering and the proven ability to demonstrate their skills in this field. The candidate is expected to demonstrate the ability to solve difficult technical problems and champion new technologies to achieve project goals. The candidate is required to be a strong team player and demonstrate scientific leadership, possessing effective oral and written communication skills for facilitating collaborations and leading cross-functional process development teams. Additional Information Applicable only to applicants applying to a position in any location with pay disclosure requirements under state orlocal law: The compensation range described below is the range of possible base pay compensation that the Companybelieves ingood faith it will pay for this role at the timeof this posting based on the job grade for this position.

Individualcompensation paid within this range will depend on many factors including geographic location, andwemayultimatelypaymore or less than the posted range. This range may bemodifiedin thefuture. We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick),medical/dental/visioninsurance and 401(k) to eligibleemployees. This job is eligible toparticipatein our long-term incentiveprograms.

Note:

No amount of payis considered to bewages or compensation until such amount is earned, vested, anddeterminable.

The amount and availability of any bonus,commission, incentive, benefits, or any other form ofcompensation and benefitsthat are allocable to a particular employeeremainsin the Company's sole andabsolutediscretion unless and until paid andmay bemodifiedat the Companys sole and absolute discretion, consistent withapplicable law. AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled. US & Puerto Rico only - to learn more, visit https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more: https://www.abbvie.com/join-us/reasonable-accommodations.html Company AbbVie's mission is to discover and deliver innovative medicines that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas: immunology, oncology, neuroscience, eye care, virology, women's health and gastroenterology, in addition to products and services across its Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com . Follow @abbvie on Twitter , Facebook , Instagram , and YouTube .

Stock Symbol:

ABBV Stock Exchange:

NYSE Company info Website http://www.abbvie.com/ Phone 1-800-255-5162 Location 1 North Waukegan Road North Chicago Illinois 60064 United States Share this job Facebook Twitter LinkedIn Apply now Send job Apply now Save job Click to add the job to your shortlist You need to sign in or create an account to save a job. Get job alerts Create a job alert and receive personalized job recommendations straight to your inbox. Create alert