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Eurofins
gRNA Process Development Scientist
Career Insights for Process Development Engineer
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Based on Massachusetts data
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What they do
A Process Development Engineer designs and implements production systems in manufacturing, engineering or mining. Develops processes that are efficient and cost effective. Plans, implements and tests production systems and processes and ensures compliance with industry and regulatory standards.
$114,840 / year median in Massachusetts
+9% projected growth
Job Description
Company DescriptionThe work we do at Eurofins Professional Scientific Services matters, and so do our employees. At Eurofins PSS, we put a focus on your professional growth. We provide our employees the ability to break into the biopharmaceutical industry and grow from the bottom up. We have the supportive teams and tools available to invest in you while also affording you work-life balance and a competitive benefits package.
Eurofins Scientific is an international life sciences company, providing a unique range of analytical testing services to clients across multiple industries, to make life and our environment safer, healthier and more sustainable. From the food you eat, to the water you drink, to the medicines you rely on, Eurofins works with the biggest companies in the world to ensure the products they supply are safe, their ingredients are authentic and labelling is accurate. Eurofins believes it is a global leader in food, environmental, pharmaceutical and cosmetics products testing and in agroscience CRO services. It is also one of the global independent market leaders in certain testing and laboratory services for genomics, discovery pharmacology, forensics, CDMO, advanced material sciences and in the support of clinical studies.
If you're looking for a rewarding career, a place to call home, apply with us today!
Job DescriptionWe are seeking a process development scientist to join the guide-RNA (gRNA) process development team. The successful candidate will be contributing to gRNA drug substance process development for programs in clinical development. In this role, the candidate will synthesize, purify, and characterize gRNAs in an effort to develop drug substance manufacturing processes and controls. Execute solid-phase synthesis and purification experiments to support process development, scale-up, and transfer of oligonucleotide drug substance manufacturing.
Execute routine analytics including HPLC and UV-Vis.
Prepare buffers, reagents, and stock solutions used for process development activities, following established recipes and SOPs.
Compile and present data to team members and key stakeholdersMaintain an updated lab notebook, order materials, maintain lab equipment, and support equipment troubleshooting as needed.
Uphold lab safety to the highest level of standards.
Experience with Tangital Flow Filtration (TFF) is required.
Ability to follow established SOPs for routine analytical support.
Experience with good documentation practices and electronic lab notebooks such as Benchling.
Unwavering commitment to safety protocols and procedures.
Strong attention to detail, organizational, and time-management skills.
Effective communication skills for collaborating with team members and conveying technical information clearly.
Strong problem-solving abilities and critical thinking skills.
Inquisitive, analytical, laboratory technique familiarity, enthusiasm to learn and contribute in a fast-paced environment.
Authorization to work in the United States indefinitely without restriction or sponsorship.
Additional InformationThe position is full-time, Monday-Friday, 8am-5pm with overtime as needed. Candidates living within a commutable distance of Boston, MA are encouraged to apply.
Excellent full-time benefits include:
Comprehensive medical coverage, dental, and vision optionsLife and disability insurance401(k) with company matchPaid vacation and holidaysEligibility for yearly goal-based bonus & merit-based increases
Eurofins Scientific is an international life sciences company, providing a unique range of analytical testing services to clients across multiple industries, to make life and our environment safer, healthier and more sustainable. From the food you eat, to the water you drink, to the medicines you rely on, Eurofins works with the biggest companies in the world to ensure the products they supply are safe, their ingredients are authentic and labelling is accurate. Eurofins believes it is a global leader in food, environmental, pharmaceutical and cosmetics products testing and in agroscience CRO services. It is also one of the global independent market leaders in certain testing and laboratory services for genomics, discovery pharmacology, forensics, CDMO, advanced material sciences and in the support of clinical studies.
If you're looking for a rewarding career, a place to call home, apply with us today!
Job DescriptionWe are seeking a process development scientist to join the guide-RNA (gRNA) process development team. The successful candidate will be contributing to gRNA drug substance process development for programs in clinical development. In this role, the candidate will synthesize, purify, and characterize gRNAs in an effort to develop drug substance manufacturing processes and controls. Execute solid-phase synthesis and purification experiments to support process development, scale-up, and transfer of oligonucleotide drug substance manufacturing.
Execute routine analytics including HPLC and UV-Vis.
Prepare buffers, reagents, and stock solutions used for process development activities, following established recipes and SOPs.
Compile and present data to team members and key stakeholdersMaintain an updated lab notebook, order materials, maintain lab equipment, and support equipment troubleshooting as needed.
Uphold lab safety to the highest level of standards.
QualificationsMinimum Required Qualifications:
B.S./M.S.
degree in chemistry, chemical engineering, or biochemistry (or related field) with at least 2 years of relevant laboratory industry experienceExperience with oligonucleotide synthesis and purification equipment (experience with gRNA or longmer synthesis and purification development is a plus)Experience operating analytical equipment such as Akta chromatography systems, Agilent U/HPLC, gel electrophoresis, and NanoDrop.Experience with Tangital Flow Filtration (TFF) is required.
Ability to follow established SOPs for routine analytical support.
Experience with good documentation practices and electronic lab notebooks such as Benchling.
Unwavering commitment to safety protocols and procedures.
Strong attention to detail, organizational, and time-management skills.
Effective communication skills for collaborating with team members and conveying technical information clearly.
Strong problem-solving abilities and critical thinking skills.
Inquisitive, analytical, laboratory technique familiarity, enthusiasm to learn and contribute in a fast-paced environment.
Preferred Qualifications:
Background in CRISPR gRNA development.Authorization to work in the United States indefinitely without restriction or sponsorship.
Additional InformationThe position is full-time, Monday-Friday, 8am-5pm with overtime as needed. Candidates living within a commutable distance of Boston, MA are encouraged to apply.
Excellent full-time benefits include:
Comprehensive medical coverage, dental, and vision optionsLife and disability insurance401(k) with company matchPaid vacation and holidaysEligibility for yearly goal-based bonus & merit-based increases
Compensation:
$32.00-$41.00 per hourEurofins USA PSS Insourcing Solutions is a Disabled and Veteran Equal Employment Opportunity employer.Benefits
- Paid Time Off (PTO)
- Dental Insurance
- Disability Insurance
- Life Insurance