Are you a clinical research expert ready for new opportunities? Would you like to play a pivotal role in the development of potential medicines? If you are passionate about being a medical leader for a cross-functional team in a group that drives action towards the improvement of global public health- join us! As Global Clinical Head (Executive Director) you will have a unique opportunity to further elevate the Infectious Disease Unit in one of the world's most respected biopharmaceutical companies. The role holds a significant development opportunity for the successful candidate whilst contributing to the positive journey that AstraZeneca is on.

Accountabilities:

The Global Clinical Head (GCH) will have overall clinical leadership of one or more global product s in the Infectious Disease pipelin e specifically related to the prevention of infections in patients with chronic respiratory diseases . The GCH is also responsible for m edical /s cientific strategies for the clinical components of the Target Product Profile (TPP), Clinical Development Plan (CDP) , and regulatory document s (e.g., briefing documents, CTD/BLA, core labelling texts ) . Within the Clinical Project Team, the GCH has accountability for the clinical, scientific , and value content and delivery of the medical components for the p rogram to time and quality. The GCH will be the team's voice and representative on the Global Project Team that oversees the overall strategy of Infectio us Disease U nit's products.

Essential Skills/Experience:

• Graduate of a recognized school of medicine with an MD degree or equivalent with board-certification in pulmonology
• Demonstrated clinical research expertise in Pulmonology (especially in COPD and bronchiectasis)
• Pharma industry experience in clinical drug development for at least 10 years
• Experience in early and late stage program development and trial conduct
• Developed/delivered in parallel multiple complex and /or large studies (e.g., including but not limited to global , pivotal Phase 3 efficacy studies)
• Demonstrated ability to lead the development of a program strategy (e.g., Clinical Development Plans) and be accountable for project plans, timelines, progress, and outcomes
• Writing and delivery of g lobal regulatory submissions (e.g., NDA/BLA submissions , benefit/risk assessment) and interacting with major Health Authorities (e.g., FDA, EMA, PMDA, CDE)
• Demonstrated ability leading and motivating teams in a matrix environment
• Demonstrated ability to lead, coach, and mentor physicians and other clinical scientists
• Significant hands-on clinical drug development experience and scientific credibility
• Demonstrated ability to cultivate excellent cross-functional collaborations
• Demonstrated ability to effectively communicate at multiple levels of the organization
• Must demonstrate high integrity
• Organize and deliver Advisory Boards with international Key Opinion Leaders (KOLs)
• Demonstrated AI/digital mindset and experience applying AI-enabled and generative AI tools to support clinical development activities (e.

g., data analysis , medical writing , clinical trial operational efficiency )

Desirable Skills/Experience :

• Infectious disease and/or vaccine expertise
• Named Investigator on a number of clinical trials
• Significant and consistent peer-reviewed publication track record When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines.

In-person working gives us the platform we need to connect, work at pace and challenge perceptions . That's why we work, on average, a minimum of three days per week from the office. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world. Why AstraZeneca? We are a changemaker on the world stage at an exciting frontier of medicine. This is backed by deep knowledge and experience in our field. Building on this, we lead the way into the future with energy and drive. We are helping to transform healthcare and build pandemic preparedness to protect against future health crises and to bring lasting immunity to people around the globe. We are committed to our central role in addressing pandemic and endemic diseases and ensuring our products continue to reach and benefit millions of people around the world. The annual base salary for this position ranges from

USD 331,873.60 - 497,810.40.

However, base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience. In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program (salaried roles) or to receive a retirement contribution (hourly roles). Benefits offered included a qualified retirement program [401(k) plan]; paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an "at-will position" and the Company reserves the right to modify base salary (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors. ​ Date Posted 19-Aug-2026 Closing Date 03-Sep-2026 Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.