Senior Histotechnologist

Senior Histotechnologist Exact Sciences paid time off United States, Wisconsin, Madison Apr 20, 2026 Help us change lives At Exact Sciences, we're helpingchange how the world prevents, detects and guides treatment for cancer. We give patients and clinicians the clarity needed to make confident decisions when they matter most. Join our team to find a purpose-driven career, an inclusive culture, and robust benefits to support your life while you're working to help others. Position Overview The Senior Histotechnologist will perform highly skilled histology and operational activities in a fast paced and complex operation. This role will perform accurate cutting on patient specimens, immunohistochemistry stain (IHC) operations, standard operating procedure (SOP) development, process development, regulatory compliance, interact with sending sites and ordering physicians, perform quality control and specimen-related checks, and comply with all applicable local, state, and federal laboratory requirements. Essential Duties Include, but are not limited to, the following: Maintain stringent standards for quality to identify any issues that might adversely impact the quality of test results and/or employee safety. Communicate issues to the appropriate management representatives to ensure prompt resolution, as needed. Perform routine and non-routine activities involved in histology, to include sectioning, and hematoxylin and eosin (H&E) staining under supervision. Independently monitor and process the histology queue for various tasks that need to be performed, with minimal supervision. Perform macro-dissection of samples under supervision. Process samples through the IHC process under supervision. Write nonconformance reports (NCRs) and deviation approval requests (DARs) according to quality assurance team outline and acceptability. Prepare reagents, solutions, and controls. Perform and document equipment maintenance and calibration. Assist in sample returns, as needed. Interact with internal pathologists, associates, and external customers in accordance with SOPs to ensure specimens are processed in a timely manner with high quality. Process specimens for research and development sponsored studies. Assist in the identification of opportunities for process improvements for histopathology. Assist in workflow, protocol, and related SOP development. Assist in equipment specification, installation, and maintenance. Participate in various studies. Provide guidance and training to research and development (R D) staff relating to histopathology. Provide summary reports on process metrics as, needed. Train new staff, as needed. Identify opportunities for process, material, vendors, and other improvements for histopathology. Contribute to corporate strategy for inspection preparation or additional regulatory approval relating to histopathology. Assist in running projects for development of histopathology around new product services and processes. Ability to integrate and apply feedback in a professional manner. Ability to prioritize and drive to results with a high emphasis on quality. Apply strong attention to detail. Ability to work independently and within a team environment. Apply strong communication skills, both written and verbal. Ability to maintain open communication with internal employees, managers, and customers, as needed. Ability to multi-task and be flexible with tasks and schedules. Strong computer skills. Excellent interpersonal skills. Uphold company mission and values through accountability, innovation, integrity, quality, and teamwork. Support and comply with the company's Quality Management System policies and procedures. Maintain regular and reliable attendance. Ability to act with an inclusion mindset and model these behaviors for the organization. Ability to work designated schedule. Ability to work overtime, as needed. Ability to work on a mobile device, tablet, or in front of a computer screen and/or perform typing for approximately 75% of a typical working day. Ability to work seated for approximately 75% of a typical working day. Ability to work standing for approximately 25% of a typical working day. Ability to lift up to 25 pounds for approximately 10% of a typical working day. Ability to grasp with both hands; pinch with thumb and forefinger; turn with hand/arm; reach above shoulder height. Ability to comply with any applicable personal protective equipment requirements. Ability to use various types of laboratory equipment; including microscopes, microtomes, blades, strainers, and pipettes for extended periods of time. May perform repetitious actions using lab tools. Ability to use near vision to view samples at close range. May be exposed to hazardous materials, tissue specimens, and instruments with moving parts, lasers, heating and freezing elements, and high-speed centrifugation. Minimum Qualifications Bachelor's Degree. 6+ years of histology lab experience with competency in dissection/scraping, microtomy/cutting, embedding, and routine staining. Demonstrated ability to perform the Essential Duties of the position with or without accommodation. Authorization to work in the United States without sponsorship. Preferred Qualifications Bachelor's Degree in Biological Sciences or Life Sciences field. Experience with digital pathology. Experience with IHC processing. American Society for Clinical Pathology (ASCP) Board of Certification, Histotechnician (HT) ASCP or Histotechnologist (HTL) ASCP. Knowledge of Clinical Laboratory Improvement Amendments (CLIA), and College of American Pathologists (CAP) regulations. #LI_KB2

Salary Range:

$69,000.00

• $122,000.00 The annual base salary shown is for this position located in US
• WI•Madison on a full-time basis.

In addition, this position is bonus eligible. Exact Sciences is proud to offer an employee experience that includes paid time off (including days for vacation, holidays, volunteering, and personal time), paid leave for parents and caregivers, a retirement savings plan, wellness support, and health benefits including medical, prescription drug, dental, and vision coverage. Learn more about our benefits. Our success relies on the experiences and perspectives of a diverse team, and Exact Sciences fosters a culture where all employees can develop personally and professionally with a sense of respect and belonging. If you require an accommodation, please contact us here. Not ready to apply? Join our Talent Community to stay updated on the latest news and opportunities at Exact Sciences. We are an equal employment opportunity employer. All qualified applicants will receive consideration for employment without regard to disability, protected veteran status, and any other status protected by applicable local, state, or federal law. To view the Right to Work, E-Verify Employer, and Pay Transparency notices and Federal, Federal Contractor, and State employment law posters, visit our compliance hub. The documents summarize important details of the law and provide key points that you have a right to know.