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MB
MBX Biosciences
Senior Director, Medical Affairs
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Based on Massachusetts data
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What they do
A Medical Director directs and manages a medical practice, clinic, lab or public health program. Organizes and manages of staff physicians, policy implementation, and ensures that standards for medical care are communicated and maintained.
$253,590 / year median in Massachusetts
+10% projected growth
Job Description
Position Summary The Senior Director, Medical Affairs (Strategy) will be a key leader responsible for developing and executing the Medical Affairs strategy across the portfolio, with an initial focus on canvuparatide as the organization advances toward commercialization. This role will provide strategic and operational leadership across scientific communications, evidence generation, publication planning, medical education, and key opinion leader (KOL) engagement, ensuring medical excellence throughout launch preparation and beyond. Partnering closely with Clinical Development, Commercial, Regulatory, and other cross-functional teams, the Senior Director will help shape the medical voice of the organization and translate scientific insights into actionable strategies. For earlier-stage programs, the role will provide targeted Medical Affairs support, including publication strategy, select KOL engagement, and advisory board activities aligned with program stage and business priorities. This position requires strong scientific credibility, strategic leadership, and the ability to thrive in a dynamic, growth-oriented environment. Key Responsibilities Lead the development and execution of the overall Medical Affairs strategy and integrated plans across the portfolio, with primary focus on canvuparatide during the peri launch and launch periods. Develop and maintain the Scientific Communication Platform (SCP) to ensure consistent, evidence-based, and compliant scientific messaging across all Medical Affairs activities. Own the forward looking publication and congress strategy, aligning data dissemination with clinical milestones, scientific priorities, and business objectives. Design and implement an integrated evidence generation strategy, including support of lifecycle management (LCM) planning in close collaboration with Clinical Development and Commercial. Build, manage, and sustain a strategic KOL engagement plan, including comprehensive KOL mapping and segmentation. Plan, lead, and execute scientific advisory boards to gather high-quality external insights that inform development, evidence generation, and strategy. Lead the development, review, and lifecycle management of Medical Affairs materials, including core scientific slide decks, Medical Information standard response letters, and foundational content to support future MSL activities. Provide Medical Affairs support to clinical trials and scientific programs, as appropriate, including investigator engagement and medical education initiatives. Design and execute scientific communication programs, such as disease awareness and educational initiatives, to advance understanding of disease and unmet need. Collaborate closely with Clinical Development, ADT, and Commercial teams to ensure medical insights are embedded in cross functional strategy, planning, and execution. Support earlier stage programs with tailored Medical Affairs activities, including publication planning, selective KOL engagement, and targeted advisory boards. Contribute to the evolution and scaling of the Medical Affairs function, supporting process development, future team buildout, and expanding responsibilities as the organization advances toward and beyond launch. Other responsibilities as assigned. Education & Qualifications Advanced scientific degree (MD, PhD, PharmD, or equivalent). 5+ years of experience in Medical Affairs or related field, with multi-TA exposure preferred. Experience leading or contributing to medical insights processes and synthesizing complex information. Proven track record in scientific communications, congress activities, and MLR review Experience in rare diseases or metabolic/endocrine conditions. Strong organizational and project management skills, with an ability to lead multiple high-priority initiatives in a dynamic, pre-launch environment. Excellent communication, scientific writing, and stakeholder-management skills. Travel You will be expected to travel periodically based on the needs of the business to the extent requested by the Company, including attendance at Together Weeks, Together Days, and functional meetings as requested by the Company.