Job Function:

Product Safety Job Sub Function:

Product Safety Risk Management MD Job Category:

Scientific/Technology All Job Posting Locations:

Horsham, Pennsylvania, United States of America, Raritan, New Jersey, United States of America, Titusville, New Jersey, United States of America Job Description:

Johnson & Johnson (J&J) is seeking a Director, Medical Safety Officer, Oncology to be located in Titusville, NJ; Raritan, NJ or Horsham, PA. Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow. Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way.

Learn more at https:

//www.jnj.com/innovative-medicine The Pharmaceuticals Medical Safety Officer (MSO) has accountability for assessing the medical safety of assigned products and will strategically lead cross-functional matrix teams responsible for product safety and benefit risk oversight and represents Global Medical Safety (GMS) as the product spokesperson regarding overall benefit/risk. The MSO will report to the Product Safety Head, Cellular Therapy, Hematology and oversee the safety and benefit/risk assessment of assigned products within the Hematology TA that are marketed and/or in clinical development. Collaborating with relevant functions, the MSO will ensure proactive and timely assessments of safety data to characterize the emerging and known safety profiles and benefit-risk assessment of assigned products within the TA. The MSO will communicate potential and known risks and changes to benefit/risk, when appropriate, to the TA Safety Head, the Head of Global Safety Strategy & Risk Management (GSSRM), the Chief Safety Officer (CSO), the Pharmaceuticals Chief Medical Officer (CMO), the Qualified Person for Pharmacovigilance (QPPV) Pharma, Senior Management, Health Authorities (HA), Prescribers and/or Patients. In compliance with legal and regulatory requirements, the MSO will also lead when appropriate, in the design and implementation of risk mitigation strategies to ensure the safe and appropriate use of Innovative Medicine products. Responsibilities include, but are not limited to the following: Strategically lead the Safety Management Teams (SMT) for assigned products. SMT responsibilities include safety surveillance (including signal detection) and risk management activities [including Risk Management Plan (RMP) and Risk Evaluation and Mitigation Strategy (REMS)], as well as other activities related to managing the safety profile of assigned products. Provide medical and scientific expertise as the GMS representative on the Compound Development Team (CDT) and Clinical Teams. Anticipate safety concerns and influence other relevant functions including Clinical teams to minimize/mitigate patient impact by active participation in the design of the clinical protocols. Be an active partner and core contributor of safety input to key regulatory or clinical documents including: Risk management plans. Safety development plan. Clinical Trial Protocols. Informed Consent Forms (ICF). Safety Sections of Investigator's Brochure (IB) and IB addenda. Clinical Study Reports (CSR). Annual Safety Reports (ASR). Integrated Safety Summary (ISS) and Summary of Clinical Safety (SCS) for

NDA/BLA/MAA

filings. Periodic Benefit Risk Evaluation Report (PBRER)/Periodic Safety Update Report (PSUR). Health authority queries. Core Data Sheets (CDS). Effectively communicate (verbally and in writing) important results of medical safety and benefit/risk management evaluations, when necessary, to the GMS Leadership Team, CMO, and the Medical Safety Council (MSC). Actively participate and contribute to meetings with Health Authorities and external key opinion leaders. Provide medical safety leadership on due diligence teams to evaluate Licensing & Acquisition opportunities. Provide medical oversight to contractors and non-physician staff involved in preparing written safety evaluations for their assigned products.

This will include:

Defining the safety question or issue requiring medical safety assessment. Developing the strategy for the safety review and analysis. Interpreting results and determining the medical importance of a question or issue. Reviewing and approving (i.e., signatory) medical assessment reports (e.g., ad hoc safety reports). Work across the GMS TAs to align and improve common processes including providing strong leadership and a harmonized approach across clinical teams for safety data collection, assessment, and safety-related processes and issues. Assist in the creation, review and implementation of new SOPs, Work Instructions, guidelines, documents, and other tools pertaining to safety assessment and risk management. Lead or actively participate in department-wide initiatives.

Minimum Qualification:

Physician (MD or equivalent) with 2-5 years of pharmacovigilance (PV) experience or other relevant experience (e.g., Clinical research, Medical Affairs, clinical) required. Board Certified/Board Eligible/equivalent preferred. Medical specialization preferred. Demonstrated skills in clinical medicine with at least 1 year of clinical practice experience. Demonstrated knowledge of principles of drug development, pharmacology, clinical trial methodology and design, medical monitoring of trials, assessment of drug risks and benefits, and safety assessment of drugs both on the market and in development and global safety regulations highly preferred. Ability to influence, negotiate and communicate with both internal and external stakeholders. Experience with Health Authority presentations is preferred.

Required Technical Knowledge and Skills:

Ability to lead global cross-functional teams effectively and strategically. Connect, collaborate, and build consensus across relevant functions. Ability to think strategically, have a global mindset, big picture orientation, Ability to see the context of the entire situation, understand implications to the business. Ability to critically evaluate safety data from multiple sources (clinical trials, environment, literature, etc.), assess clinical importance and potential strategic impact of the data and present the findings clearly in both written and oral communications. Experience and knowledge of Good Clinical Practices and Pharmacovigilance regulatory requirements in US, the EU and globally, the conduct of clinical trials and for the appropriate contributions to regulatory filings, PV documents and risk management plans. Able to plan work to meet deadlines and effectively handle multiple priorities. Excellent verbal and written communication skills, including formal presentation skills. Written skills as evidenced by publication and journal articles are also desirable. Fluent in written and spoken English. Proficiency in Word and PowerPoint is desired. Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act. Johnson & Johnson is committed to providing an interview process that is inclusive of our applicants' needs. If you are an individual with a disability and would like to request an accommodation, please contact us via https://www.jnj.com/contact-us/careers or contact AskGS to be directed to your accommodation resource. #

LI-Hybrid Required Skills:

Preferred Skills:

Clinical Operations, Compliance Management, Compliance Risk, Consulting, Design Mindset, Developing Others, Leadership, Medicines and Device Development and Regulation, Operational Excellence, Quality Control (QC), Research Ethics, Risk Management, Safety Investigations, Safety-Oriented, Serious Adverse Event Reporting, Standard Operating Procedure (SOP), Succession Planning, Surveillance The anticipated base pay range for this position is : $199,000.00

$343,850.

00 Additional Description for

Pay Transparency:

Subject to the terms of their respective plans, employees are eligible to participate in the Company's consolidated retirement plan (pension) and savings plan (401(k)). Subject to the terms of their respective policies and date of hire, employees are eligible for the following time off benefits:

Vacation
120 hours per calendar year
Sick time
40 hours per calendar year; for employees who reside in the State of Colorado
48 hours per calendar year; for employees who reside in the State of Washington
56 hours per calendar year
Holiday pay, including Floating Holidays
13 days per calendar year
Work, Personal and Family Time
up to 40 hours per calendar year
Parental Leave
480 hours within one year of the birth/adoption/foster care of a child
Bereavement Leave
240 hours for an immediate family member: 40 hours for an extended family member per calendar year
Caregiver Leave
80 hours in a 52-week rolling period10 days
Volunteer Leave
32 hours per calendar year
Military Spouse Time-Off
80 hours per calendar year For additional general information on Company benefits, please go to:
https://www.

careers.jnj.com/employee-benefits At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity.

Learn more at https:

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