Scope of the role:

\nThe Vice President of Human Resources, US is the senior HR leader for the United States organization and a trusted advisor to the US leadership team. This role owns the full HR agenda across the employee lifecycle and plays a critical role in organizational growth, transformation, and integration. You will lead a local HR team, partner closely with global Centers of Excellence (COEs), and ensure that all people programs are effectively deployed and embedded across US business. This is a hands-on, visible leadership role for someone confident in their expertise, comfortable navigating complexity, and energized by change.

Key Job Responsibilities:

Strategic Leadership & Business Partnership Act as a trusted advisor and coach to senior leaders, supporting leadership effectiveness, decision-making, and organizational health Partner closely with the US Leadership Team and global HR COEs to align people strategy with business priorities Translate global HR strategy into impactful, locally relevant execution across the US Growth, M&A & Transformation Lead HR aspects of mergers, acquisitions, integrations, and divestitures, including scaling the organization by 100+ employees Drive organizational design, restructuring, and reorganization efforts as the business evolves Support change management initiatives during periods of transformation HR Operations & Team Leadership Lead and develop the US HR team of 4-5 professionals to ensure strong execution across talent acquisition, compensation & benefits, employee relations, performance management, and compliance Talent & Leadership Development Champion leadership development and coaching at all levels of the organization Foster a high-performance, respectful, and inclusive culture Ensure succession planning and talent pipelines are in place for critical roles Program Deployment & Governance Ensure all global HR programs and initiatives are effectively rolled out and adopted in the US Maintain strong governance, compliance, and HR best practices aligned with US labor laws and pharma industry standards Who are you? BS degree and 10+ years of experience\nProven experience as a Head of HR / HR Director / Senior HR Leader in the US, ideally within pharmaceuticals, life sciences, or a highly regulated industry Strong track record in M&A, organizational design, restructuring, and scaling organizations Experience leading and developing multi-disciplinary HR teams Confident, bold, and respectful leadership style—comfortable standing firm while building trust Highly skilled in coaching senior leaders and navigating complex stakeholder environments Collaborative mindset with the ability to work seamlessly with global COEs Hands-on, pragmatic, and execution-focused Why Join Alfasigma? At Alfasigma, we foster a culture where the courage to innovate is key to our success. We offer a competitive salary, comprehensive benefits, and extensive opportunities for professional growth and development. Our commitment to people and patients is at the heart of everything we do. We value diversity and welcome individuals with unique perspectives and experiences. We believe that open-mindedness, collaboration, and a shared passion for innovation are essential to achieving meaningful progress. Join Alfasigma and become part of a forward-thinking team dedicated to shaping the future of the pharmaceutical industry.\n

Compensation & Benefits:

The anticipated salary range for this position is $325,000-400,000. This represents the anticipated low and high end of the salary range for this position. Actual salaries may vary based on various factors including, but not limited to, experience, skillset, and performance. The salary range listed is just one component of our total compensation package. Alfasigma US also provides a competitive suite of benefits, including:\n

401(k) plan with company match\n
Rewards and recognition program\n
Health care benefits (medical, prescription drugs, dental, and vision insurance)\n
Short and long-term disability coverage provided\n
Plan coverage for domestic partners\n
Paid parental leave benefits and adoption assistance\n
Tuition reimbursement assistance\n
A generous Paid Time Off program\n
Numerous well-being and work/life programs EEO Statement Employment decisions at the Company are made without unlawful regard to race, color, religion, creed, national origin, alienage or citizenship status, sex (including gender, pregnancy, childbirth or medical conditions related to pregnancy or childbirth), gender identity or expression, sexual orientation, national origin, ethnicity, age, physical or mental disability, legally protected genetic information, marital or partnership status, sexual and reproductive health decisions, military or veteran status, or any other status protected by applicable federal, state, or local law.

This organization participates in E-Verify (E-Verify's Right to Work guidance can be found here: https://www.e-verify.gov/sites/default/files/everify/posters/IER_RighttoWorkPoster.pdf). 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