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At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters. The Position At Roche, we are developing the next-generation of sequencing systems. By accelerating clinical research, streamlining workflows, and expanding assay menus, we are also broadening access to genomic data and lowering barriers to adoption. From robust sample isolation and preparation tools to novel sequencing technology and advanced bioinformatics, we are developing differentiated, highly integrated end-to-end solutions for next-generation sequencing workflows. Our Systems Technology Group, a part of Roche Sequencing Solutions, is focused on creating and advancing technologies to significantly enhance DNA sequencing workflows. We are seeking a Senior Research Engineer to contribute to the design, development, characterization, and integration of cutting-edge sequencing systems. This is a hands-on role focused on solving the fluidic and consumable challenges at the heart of our next-generation platforms. We are looking for someone who exhibits a high degree of motivation, independence, and resourcefulness to help us develop solutions to our automation challenges in a fast-paced and collaborative environment. The Opportunity You will contribute to the research and early development of specialized consumables and related hardware for next-generation sequencing systems.. You will design, fabricate, assemble, characterize, troubleshoot and optimize custom devices, consumables, test fixtures and breadboards. You will evaluate different concepts and design paths to assess feasibility. Collect and present data and findings to the team and participate in or drive down-selection efforts. You will create and maintain comprehensive design documentation for your sub-systems, including requirements, schematics, diagrams, CAD models, manufacturing drawings, and material specifications. You will contribute to the acquisition, installation, bring-up, utilization and maintenance of new tools and equipment for use in the fabrication or testing of devices and consumables
Who You Are:
(Required) You have a Bachelor's in Mechanical Engineering (or a closely related discipline), with 4+ years of relevant industry experience; or a Master's in Mechanical Engineering (or a closely related discipline), with 2+ years of relevant industry experience; or a PhD in in Mechanical Engineering (or a closely related discipline), with 1+ years of relevant industry experience. You have 3+ years working with various fluidic devices You have demonstrated hands-on experience characterizing and testing complex fluidic systems and consumable interfaces for life science or diagnostic instrumentation. You have experience in experimental design for fluidic characterization and the use of Python for device control, automated test bench execution, and data acquisition/analysis. You have a demonstrated level of proficiency with machine shop tools, measurement equipment, and rapid prototyping technologies. You have a demonstrated level of troubleshooting skills, with a solid understanding of physics, chemistry and engineering fundamentals. You have experience working with deadlines, in a collaborative setting and a high level of scientific curiosity.
Preferred Qualifications:
You have an advanced degree in Mechanical Engineering You have experience using fluidic diagramming tools and CFD or FEA tools to guide fluidic and thermal design decisions. You have experience with DNA sequencing, DNA synthesizers and other complex fluidic automation instrumentation You have experience working with scientists and chemists to solve multi-disciplinary problems. You have experience with advanced microfabrication techniques, including lithography, thin-film deposition and wet etching of metals and inorganic materials. You have experience in SolidWorks for detailed part and assembly design and the creation of manufacturing drawings. This is an on-site position based in Santa Clara, CA. (This is not a hybrid position.) Relocation benefits are not being offered for this role. The expected salary range for this position based on the primary location Santa Clara, CA is $87,500 - $162,500. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below. Benefits Who we are A healthier future drives us to innovate. Together, more than 100'000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact. Let's build a healthier future, together. Roche is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws. If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants . Explore Location Close the popup Apply Now Save job Job Advanced Widget Sub Category Design Engineering & Architecture Job Type Full time Job Level Individual Contributor Posted Date 07-26-2026 Posting End Date • 07-31-2026 Job Type Regular / Permanent If there is a posting end date listed above, the job will close at 11:59pm on the previous day, using the time zone of the location of the job. Get tailored job recommendations based on your interests. Get Started profile icon 4 hours. Profile recommendations See more Show less See next See even more No recommendations found Similar Jobs Senior Mechanical Engineer, Research & Early Development Location Santa Clara, California, United States of America Category Engineering Senior Systems Engineer Location Santa Clara, California, United States of America Category Engineering Systems Engineer - Diagnostics Available in 2 locations Category Engineering Lead SDET (Software Development Engineer in Test) Location Carlsbad, California, United States of America Category Engineering No recommendations found Jobseekers Also Viewed See more See less See next See even more No recommendations found Share this Opportunity Share via LinkedIn Share via Facebook Share via twitter Share via email Share job link To your colleagues or friends Cancel Copy Link
