Post Doctoral Research Associate

Post Doctoral Research Associate  Salary $55,000.00 - $65,000.00 Annually Location DSU Main Campus, 1200 N Dupont Highway, Dover Job Type Professional Job Number 2025-00424 Division CAST Department

CHEMISTRY

Opening Date 05/20/2026 DESCRIPTION BENEFITS General Description of the Position The Post-Doctoral Associate will work closely with the Principal Investigator using biochemical and molecular biology techniques to develop targeted small protein therapeutics that aim to induce an immune response by targeting specific proteins in cancer cells. Essential Functions & Required Knowledge, Skills and Abilities The following are the functions essential to performing this job: 1. Carry out experiments to develop and validate small proteins that have high affinity and selectivity for cancer cells 2. Assist with preparation of manuscripts for submission to scientific journals and conferences 3. Performs literature studies and writes technical reports 4. Assist in training and mentoring lab personnel, including graduate and undergraduate students. 5. Organizes and attends research group and sub-group meetings. Other Functions Individual in this job may be assigned one or more of the following tasks on a rotating or as-needed basis: 1. Oversees image analysis projects and works with other lab members 2. Presents the lab's research work at regional, national, and international scientific meetings and conferences 3. Attends workshops/seminars on protein engineering and discovery 4. Attends workshops/seminars on computational aided drug discovery Required Knowledge, Skills, and Abilities The individual in this job must possess these skills and abilities or be able to explain and demonstrate that they can perform the essential functions of the job, with reasonable accommodation, or using some other combination of skills and abilities: 1. Demonstrated experience in protein engineering, expression, purification, and biochemical characterization 2. Demonstrated experience in cell-based assays such as ELISA , flow cytometry binding, BLI 3. Expertise in molecular biology techniques such as cloning, PCR, mutagenesis, DNA extraction, gel electrophoresis 4. Knowledge of protein/antibody discovery and optimization using in vitro display (such as phage or yeast) technology 5. Knowledge of two-hybrid assay screening, focusing on studying molecular interactions, such as protein-protein, protein-DNA, and protein-RNA interactions 6. Strong analytical and problem-solving skills 7. Excellent communication and collaborative abilities 8. Works well as part of a diverse, multicultural team Qualification Standards 1.

Education:

PhD (required) in Chemistry, Biochemistry, Biology, Molecular Biology or related area. 2. Experience in expression, purification, characterization and optimization of recombinant proteins. 3. Experience with design, execute, and troubleshoot SPR and BLI-based assays, including binding kinetics, blocking, affinity, competition, and epitope binning 4.

Other preferences:

Familiarity with de novo protein design Performance Standards & EEO Statement The criteria for evaluation in this position include, but are not limited to, the following: 1. Demonstrates knowledge of the DSU Fundamentals 2. Demonstrates ability to manage day-to-day operations of the project per directives of PI