Student Assistant (Multiple Vacancies)

Position Summary:

Rutgers, The State University of New Jersey, is seeking a Student Assistant for the department of Neurology at the Robert Wood Johnson Medical School. The mission of the lab is to study how lipid dysregulation is involved in the pathogenesis of Parkinson's disease. Simultaneously, the lab aspires to remain at the cutting edge in terms of cellular and molecular biology techniques and to advance the neurodegeneration field by developing innovative tools and technologies that we will share with the research community. To achieve those goals, we are currently using mammalian cell lines (including stable cell lines) for cell and molecular biology experiments including flow cytometry, microscopy (standard imaging and

FRET , FLIM , FRAP

), proteomics, lipidomics and transcriptomics analyses. We are also expanding to iPSC-neurons and in vivo work, including c. elegans and sea lamprey model systems. Under the direction of the Principal Investigator, the incumbent will work on a project in a laboratory dedicated to studying the molecular pathogenesis of Parkinson's Disease, identifying therapeutic targets and testing new therapeutic agents. Student Assistant will work in a new lab as part of a highly integrated research team utilizing a variety of laboratory technologies and approaches. Appropriate training in all techniques necessary for the project will be provided. The applicant will join in ongoing research projects. Contributions to our research will be appropriately acknowledged through co-authorship on published manuscripts. Among the key duties of this position are the following: Carry out studies with cultured cell lines and iPSc derived neurons. Optimize assays to model and study specific disease processes of neurodegenerative diseases and miniaturize them to enable high throughput screens. Perform high throughput genetic and chemical screens. Perform proteomics, lipidomics, genomics and transcriptomics experiments and analyses, in collaboration with core facilities at Rutgers. Undertake histology, genetics and biochemistry experiments on human neuropathological materials. Perform molecular biology experiments that involve cloning of specific cDNAs in various vectors including viral vectors, PCR, sequence analyses, transcription assays, Western blotting, DNA-protein interaction, and cell biologic studies. Undertake bioinformatics analyses of imaging, genomics, transcriptomics and proteomics data, as well as statistical analyses of biological data and any other types of analyses that might arise.

Minimum Education and Experience:

Must be current Rutgers student. Must have undertaken coursework in at least one of the following: Biology, Chemistry, Biochemistry or related disciplines. Previous research experience is required.

City:

Piscataway State:

NJ Physical Demands and Work Environment:

Physical Demands:

Ability to perform pipetting, measuring weights and volumes accurately, standing on feet and walking to other buildings on the campus. Occasionally, certain heavy items in the laboratory may need to be lifted, such as small equipment, boxes and bottles. Ability to operate standard laboratory equipment such as centrifuges, culture hoods, incubators, PCR machines, shaking incubators and plate readers.

Work Environment:

Lab environment. Moderate Noise.

Posting Number:

26ST1328