Cell Line Development

Cell Line Development at Avid Bioservices Cell Line Development at Avid Bioservices in Aliso Viejo, California Posted in about 15 hours ago.

Type:

full-time

Job Description:

As a Cell Line Development Scientist , you will play a critical role in establishing high-performing mammalian cell lines that enable early-phase biologics programs. This position offers the opportunity to shape foundational capabilities in a fast-paced, collaborative environment focused on innovation and client success. Design and execute strategies for stable cell line development using CHO cell line systems. Perform hands-on CHO cell line development and characterization studies, including transfection, selection, single cell subcloning, growth and productivity screening, cell banking and stability assessment of cell banks. Culture mammalian cells across multiple scales and formats, from 96-well plates up to large shake flasks, experience with ambr 250 and bioreactors is ideal. Implement high-throughput screening and automation tools for clone evaluation. Maintain rigorous documentation and ensure compliance with quality and regulatory standards. Author and review cell line development reports, summaries, and presentations. Present updates at client and cross-functional meetings. Partner with Upstream and Downstream Process Development and Analytical teams to deliver integrated solutions. Contribute to technology evaluations and continuous improvement initiatives for cell line workflows.

Minimum Qualifications:

M.S. in Cell Biology, Molecular Biology, Biochemistry, or related field. 2-5 years of industry experience in cell development for biologics. Hands-on experience with CHO cell systems, transfection methods, and clone screening for production of monoclonal antibodies, antibody-like molecules, enzymes, cytokines, bi-specifics and other recombinant molecules. Strong knowledge of mammalian cell culture, molecular biology techniques and bio process engineering concepts. Proficient in aseptic mammalian cell culture techniques. Familiarity with automation platforms and data analysis tools. Excellent problem-solving and communication skills.